stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Zackler J et al. | A mass screening program for the detection of gonorrhea. | 1972 | Am. J. Obstet. Gynecol. | pmid:4623083 |
Wahle KW and Garton GA | Desaturation of stearate by sheep tissue microsomal preparations. | 1972 | Biochem. J. | pmid:4643297 |
Lesslauer W and Blasie JK | Direct determination of the structure of barium stearate multilayers by x-ray diffraction. | 1972 | Biophys. J. | pmid:5057749 |
Price CJ and Rowe CE | Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. | 1972 | Biochem. J. | pmid:5075269 |
Patil GS et al. | Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. | 1972 | J. Lipid Res. | pmid:5075503 |
Kannangara CG and Stumpf PK | Fat Metabolism in Higher Plants: XLVII. The Effect of Nitrite and Other Anions on the Formation of Unsaturated Fatty Acids by Isolated Chloroplasts. | 1972 | Plant Physiol. | pmid:16657990 |
Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. | 1972 | Yakugaku Zasshi | pmid:4675495 |
Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
McLeay AC and Beveridge J | Clinical trial of erythromycin stearate suspension. | 1971 | Med. J. Aust. | pmid:4929585 |
Schmidt P et al. | [Acute inhalation toxicity of cadmium stearate]. | 1971 | Z Gesamte Hyg | pmid:5123074 |
Caille MP et al. | [Acute forms of lead poisoning by lead stearate]. | 1971 | Arch Mal Prof | pmid:5123552 |
Bell SM | A comparison of absorption after oral administration of erythromycin estolate and erythromycin stearate. | 1971 | Med. J. Aust. | pmid:5134726 |
Givan CV and Stumpf PK | Fat Metabolism in Higher Plants: XLV. Some Factors Regulating Fatty Acid Synthesis by Isolated Spinach Chloroplasts. | 1971 | Plant Physiol. | pmid:16657651 |
Smith DD | Clinical trial of erythromycin stearate suspension. | 1971 | Med. J. Aust. | pmid:5577264 |
Carlisle HN and Saslaw S | Therapy of staphylococcal infections in monkeys. VI. Comparison of clindamycin, erythromycin, and methicillin. | 1971 | Appl Microbiol | pmid:4994902 |
Nossel HL et al. | Inhibition of collagen-induced platelet aggregation by normal plasma. | 1971 | J. Clin. Invest. | pmid:4107268 |
SHABANOVA IA | MYOCARDIAL FATTY ACIDS IN NORMAL RABBITS AND RABBITS WITH EXPERIMENTAL MYOCARDITIS. | 1965 Mar-Apr | Fed Proc Transl Suppl | pmid:14304768 |
SINGLETON WS | CHARACTERIZED OILS FOR USE IN INTRAVENOUS FAT EMULSIONS. | 1965 | Am. J. Clin. Nutr. | pmid:14262113 |
NORKIN SA et al. | EFFECT OF ALBUMIN AND FATTY ACIDS ON CELLULAR GROWTH IN VITRO. | 1965 | Arch Pathol | pmid:14322948 |
VADEHRA DV and HARMON LG | ACTION OF LIPASES OF STAPHYLOCOCCUS AUREUS ON MILK FAT. | 1965 | Appl Microbiol | pmid:14325270 |