stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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HANSEN IA | SELECTIVE INCORPORATION OF FATTY ACIDS INTO LIPIDS OF LAMB AND RAT INTESTINAL MUCOSA. | 1965 | Comp. Biochem. Physiol. | pmid:14348000 |
SCHROEPFER GJ and BLOCH K | THE STEREOSPECIFIC CONVERSION OF STEARIC ACID TO OLEIC ACID. | 1965 | J. Biol. Chem. | pmid:14253467 |
SCHWARTZ S et al. | LIPID THROMBOPLASTINS AND MYOCARDIAL INFARCTION. | 1965 | Am. J. Med. Sci. | pmid:14254823 |
NEWLAND J et al. | PHOSPHORUS METABOLISM IN VIRAL-INDUCED NEOPLASIA. II. IN VIVO AND IN VITRO STUDIES OF THE MILK AND MAMMARY GLAND LIPIDES OF STRAINS OF MICE SUSCEPTIBLE TO THE MAMMARY TUMOR VIRUS. | 1965 | Can. J. Biochem. | pmid:14329900 |
NOBLE RC and MOORE JH | FURTHER STUDIES ON THE LIPID METABOLISM OF THE NORMAL AND VITAMIN B-12 DEFICIENT CHICK EMBRYO. | 1965 | Biochem. J. | pmid:14333549 |
WINTER CA and FLATAKER L | NOCICEPTIVE THRESHOLDS AS AFFECTED BY PARENTERAL ADMINISTRATION OF IRRITANTS AND OF VARIOUS ANTINOCICEPTIVE DRUGS. | 1965 | J. Pharmacol. Exp. Ther. | pmid:14334273 |
DICOSTANZO G and CLEMENT J | ["IN VIVO" INCORPORATION OF TRITIATED OLEIC, STEARIC AND PALMITIC ACIDS INTO LIPIDS OF RAT INTESTINAL LUMEN AND MUCOSA. IMPORTANCE OF SUPPLY OF ENDOGENOUS FATTY ACIDS]. | 1965 | Bull. Soc. Chim. Biol. | pmid:14334811 |
SRIDHARA S and BHAT JV | FURTHER INVESTIGATIONS OF THE INCORPORATION OF (1-14C)ACETATE INTO THE LIPIDS OF THE SILKWORM BOMBYX MORI L. | 1965 | Biochem. J. | pmid:14340061 |
BOUCROT P and CLEMENT J | [SUPPLY OF ENDOGENOUS FATTY ACIDS IN RAT LYMPH FOLLOWING ADMINISTRATION OF A MEAL CONTAINING MIXED C14-STEARIC: H3-OLEIC TRIGLYCERIDES]. | 1965 | C. R. Hebd. Seances Acad. Sci. | pmid:14341956 |
ROOTS BI and JOHNSTON PV | LIPIDS OF ISOLATED NEURONS. | 1965 | Biochem. J. | pmid:14342249 |
KANFER J | OBSERVATIONS ON CEREBROSIDE METABOLISM IN VIVO. | 1965 | J. Biol. Chem. | pmid:14275111 |
KEITEL HG and CHU E | PREMATURE INFANT FEEDING. I. THE CLINICAL USEFULNESS OF CALORIC CONCENTRATION OF FORMULAS, OF EARLY VERSUS LATE FEEDINGS AND OF LOW STEARIC ACID CONTENT FORMULAS. | 1965 | Pediatr. Clin. North Am. | pmid:14276882 |
KORN ED et al. | SYNTHESIS OF UNSATURATED FATTY ACIDS IN THE SLIME MOLD PHYSARUM POLYCEPHALUM AND THE ZOOFLAGELLATES LEISHMANIA TARENTOLAE, TRYPANOSOMA LEWISI, AND CRITHIDIA SP.: A COMPARATIVE STUDY. | 1965 | J. Lipid Res. | pmid:14280472 |
BACHUR NR et al. | FATTY ACID AMIDES OF ETHANOLAMINE IN MAMMALIAN TISSUES. | 1965 | J. Biol. Chem. | pmid:14284696 |
HANSEN HJ et al. | THE EFFECT OF WHOLE-BODY X-IRRADIATION ON THE SYNTHESIS OF INDIVIDUAL FATTY ACIDS IN LIVER SLICES FROM NORMAL AND FASTED RATS. | 1965 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:14309652 |
LAMBREMONT EN | BIOSYNTHESIS OF FATTY ACIDS IN ASEPTICALLY REARED INSECTS. | 1965 | Comp. Biochem. Physiol. | pmid:14314981 |
ANSTALL HB and TRUJILLO JM | DETERMINATION OF FREE FATTY ACIDS IN PLASMA BY A COLORIMETRIC PROCEDURE: AN APPRAISAL OF THE METHOD AND COMPARISON WITH OTHER TECHNICS. | 1965 | Clin. Chem. | pmid:14319230 |
SHAFRIR E et al. | PARTITION OF FATTY ACIDS OF 20-24 CARBON ATOMS BETWEEN SERUM ALBUMIN AND LIPOPROTEINS. | 1965 | Biochim. Biophys. Acta | pmid:14320230 |
GOERANSSON G | THE METABOLISM OF FATTY ACIDS IN THE RAT. IV. STEARIC ACID. | 1965 | Acta Physiol. Scand. | pmid:14321752 |
Keys A et al. | Serum cholesterol response to changes in the diet: IV. Particular saturated fatty acids in the diet. | 1965 | Metab. Clin. Exp. | pmid:25286466 |