stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Soler-Argilaga C et al. | The effect of sex on the quantity and properties of the very low density lipoprotein secreted by the liver in vitro. | 1976 | J. Lipid Res. | pmid:178815 |
Uyesaka N et al. | Lanthanum and some other cation-induced changes in fluidity of synaptosomal membrane studied with nitroxide stearate spin labels. | 1976 | J. Membr. Biol. | pmid:181579 |
Miller RW and De La Roche IA | Properties of spin labelled membranes of Fusarium oxysporum f. sp. lycopersici. | 1976 | Biochim. Biophys. Acta | pmid:182261 |
Ruf HH and Gratzl M | Binding of nitroxide stearate spin labels to bovine serum albumin. | 1976 | Biochim. Biophys. Acta | pmid:184832 |
Todorow S and Elies W | [Oily contrast medium in liquor space following myelography. A clinical-radiological study on extent, velocity and ways of elimination of monoiodine stearate]. | 1976 | Neurochirurgia (Stuttg) | pmid:185538 |
Marai L et al. | Identification of isomeric doxyl stearic acids by gas-liquid chromatography and mass spectrometry. | 1976 | Chem. Phys. Lipids | pmid:186203 |
Björkhem I | On the mechanism of regulation of omega oxidation of fatty acids. | 1976 | J. Biol. Chem. | pmid:956185 |
Steffen DG and Platner WS | Subcellular membrane fatty acids of rat heart after cold acclimation or thyroxine. | 1976 | Am. J. Physiol. | pmid:961919 |
Adachi H et al. | Effect of long-chain acyl-CoA on the omega-oxidation of monocarboxylic acid. | 1976 | Hokkaido Igaku Zasshi | pmid:985795 |
Porra RJ and Stumpf PK | Lipid biosynthesis in developing and germinating soybean cotyledons. The formation of palmitate and stearate by chopped tissue and supernatant preparations. | 1976 | Arch. Biochem. Biophys. | pmid:987755 |
Weber J et al. | [Can zinc stearate cause lung fibrosis? (Case report)]. | 1976 | Beitr Silikoseforsch Pneumokoniose | pmid:990095 |
Yamashita T et al. | [Studies on erythromycin stearate capsules (OE-7) (author's transl)]. | 1976 | Jpn J Antibiot | pmid:933342 |
Thies C | Development of injectable microcapsules for use in the treatment of narcotic addiction. | 1976 | Natl Inst Drug Abuse Res Monogr Ser | pmid:967230 |
Gray AP and Guardina WJ | Long-acting narcotic antagonist complexes. | 1976 | Natl Inst Drug Abuse Res Monogr Ser | pmid:967231 |
Eliasz AW et al. | Phospholipid phase transitions. Effects of n-alcohols, n-monocarboxylic acids, phenylalkyl alcohols and quaternary ammonium compounds. | 1976 | Biochim. Biophys. Acta | pmid:971432 |
Graham KC et al. | Simple thin-layer chromatographic identification method for erythromycin stearate. | 1976 | J. Chromatogr. | pmid:977688 |
Matsuda Y et al. | Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression. | 1976 | J Pharm Sci | pmid:978434 |
Fee JV et al. | Influence of hydrophobic materials on dissolution of a nondisintegrating hydrophilic solid (potassium chloride). | 1976 | J Pharm Sci | pmid:1255446 |
Yamashita T et al. | [Blood concentration and urinary excretion in human of OE-7, a gastric hard capsule containing enteric-coated granules. I (author's transl)]. | 1976 | Jpn J Antibiot | pmid:1263346 |
Norwitz G and Galan M | Determination of barium and strontium peroxides (active oxygen) in igniters in small-arms tracer ammunition. | 1976 | Talanta | pmid:18961958 |