stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kumar RV and Sinha VR | Tailoring of drug delivery of 5-fluorouracil to the colon via a mixed film coated unit system. | 2011 | Acta Pharm | pmid:21945913 |
MuselÃk J et al. | Influence of process parameters on content uniformity of a low dose active pharmaceutical ingredient in a tablet formulation according to GMP. | 2014 | Acta Pharm | pmid:25296681 |
Varshosaz J et al. | Optimization of self-assembling properties of fatty acids grafted to methoxy poly(ethylene glycol) as nanocarriers for etoposide. | 2012 | Acta Pharm | pmid:22472447 |
Saroja C and Lakshmi PK | Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. | 2013 | Acta Pharm | pmid:23482314 |
Someshwar K et al. | Formulation and evaluation of effervescent floating tablets of tizanidine hydrochloride. | 2011 | Acta Pharm | pmid:21684848 |
Pani NR et al. | Compatibility studies of nateglinide with excipients in immediate release tablets. | 2011 | Acta Pharm | pmid:21684850 |
BRZIN B | COMPARATIVE STUDIES ON ANAEROBIC CORYNEBACTERIA AND ACTINOMYCETES. | 1965 | Acta Pathol Microbiol Scand | pmid:14322324 |
Wadström T et al. | Hydrophobized wound dressing in the treatment of experimental Staphylococcus aureus infections in the young pig. | 1985 | Acta Pathol Microbiol Immunol Scand B | pmid:2417448 |
Sanjurjo P et al. | Plasma fatty acid composition during the first week of life following feeding with human milk or formula. | 1988 | Acta Paediatr Scand | pmid:3354331 |
Paavolainen M et al. | Penetration of erythromycin stearate into maxillary sinus mucosa and secretion in chronic maxillary sinusitis. | 1977 Sep-Oct | Acta Otolaryngol. | pmid:199040 |