stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zackler J et al. | A mass screening program for the detection of gonorrhea. | 1972 | Am. J. Obstet. Gynecol. | pmid:4623083 |
| Wahle KW and Garton GA | Desaturation of stearate by sheep tissue microsomal preparations. | 1972 | Biochem. J. | pmid:4643297 |
| Conte U et al. | The effect of magnesium stearate and polytetrafluoroethylene as lubricants in direct compression of acetylsalicylic acid. | 1972 | Farmaco Prat | pmid:5049531 |
| Lesslauer W and Blasie JK | Direct determination of the structure of barium stearate multilayers by x-ray diffraction. | 1972 | Biophys. J. | pmid:5057749 |
| Price CJ and Rowe CE | Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. | 1972 | Biochem. J. | pmid:5075269 |
| Patil GS et al. | Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. | 1972 | J. Lipid Res. | pmid:5075503 |
| Kannangara CG and Stumpf PK | Fat Metabolism in Higher Plants: XLVII. The Effect of Nitrite and Other Anions on the Formation of Unsaturated Fatty Acids by Isolated Chloroplasts. | 1972 | Plant Physiol. | pmid:16657990 |
| Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. | 1972 | Yakugaku Zasshi | pmid:4675495 |
| Ryan DC et al. | Estolate and stearate forms of erythromycin in the treatment of acute beta haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4568626 |
| Bond JM et al. | The second international reference preparation of procaine benzylpenicillin in oil with aluminium monostearate. | 1973 | Bull. World Health Organ. | pmid:4541152 |
| Arya OP and Bosa CB | In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. | 1973 | Br J Vener Dis | pmid:4748409 |
| McLeay A and Cooke P | Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4694278 |
| Norwitz G and Gordon H | Determination of lithium stearate in sebacate-based lubricants by atomic absorption. | 1973 | Talanta | pmid:18961363 |
| Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. | 1973 | Yakugaku Zasshi | pmid:4797567 |
| Antimicrobial efficacy of erythromycin stearate. A report from the general Practitioner Research Group. | 1974 | Practitioner | pmid:4591200 | |
| Caldwell HC | Dissolution of lithium and magnesium from lithium carbonate capsules containing magnesium stearate. | 1974 | J Pharm Sci | pmid:4830001 |
| Beleslin DB et al. | Hyperthermic effect of palmitate sodium, stearate sodium and oleate sodium injected into the cerebral ventricles of conscious cats. | 1974 | Neuropharmacology | pmid:4840846 |
| Kasuya M et al. | Toxic effect of cadmium stearate on rat cerebellum in culture. | 1974 | Bull Environ Contam Toxicol | pmid:4474041 |
| McGee R and Spector AA | Fatty acid biosynthesis in Erlich cells. The mechanism of short term control by exogenous free fatty acids. | 1975 | J. Biol. Chem. | pmid:237919 |
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| Anderson RR et al. | Composition of cottontail rabbit milk from stomachs of young and directly from gland. | 1975 | J. Dairy Sci. | pmid:1184805 |
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| Gray AP and Guardina WJ | Long-acting narcotic antagonist complexes. | 1975 | Natl Inst Drug Abuse Res Monogr Ser | pmid:1234981 |
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| Aveldano MI and Bazán NG | Rapid production of diacylglycerols enriched in arachidonate and stearate during early brain ischemia. | 1975 | J. Neurochem. | pmid:1206411 |
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| Wood R | Sterospecific analysis of hepatoma, host liver, and normal rat liver triglycerides from animals on chow and fat free diets. | 1975 | Lipids | pmid:167260 |
| Iot T et al. | Synthesis of a new phosphatidylserine spin-label and calcium-induced lateral phase separation in phosphatidylserine-phosphatidylcholine membranes. | 1975 | Biochemistry | pmid:167814 |
| Thompson W and MacDonald G | Isolation and characterization of cytidine diphosphate diglyceride from beef liver. | 1975 | J. Biol. Chem. | pmid:169258 |
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| Asker AF et al. | Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions. | 1975 | Pharmazie | pmid:169527 |
| Phadke RS | Sedimentation test for procaine benzylpenicillin in oil with aluminium monostearate. III. Substitution of the sedimentation rate for the blood-level duration test of WHO in rabbits. | 1975 Aug-Nov | Hindustan Antibiot Bull | pmid:1236093 |
| Koroly MJ and Conner RL | Unsaturated fatty acid biosynthesis in Tetrahymena. Evidence for two pathways. | 1976 | J. Biol. Chem. | pmid:826532 |
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| Björkhem I | On the mechanism of regulation of omega oxidation of fatty acids. | 1976 | J. Biol. Chem. | pmid:956185 |
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| Adachi H et al. | Effect of long-chain acyl-CoA on the omega-oxidation of monocarboxylic acid. | 1976 | Hokkaido Igaku Zasshi | pmid:985795 |
| Porra RJ and Stumpf PK | Lipid biosynthesis in developing and germinating soybean cotyledons. The formation of palmitate and stearate by chopped tissue and supernatant preparations. | 1976 | Arch. Biochem. Biophys. | pmid:987755 |
| Weber J et al. | [Can zinc stearate cause lung fibrosis? (Case report)]. | 1976 | Beitr Silikoseforsch Pneumokoniose | pmid:990095 |
| Yamashita T et al. | [Studies on erythromycin stearate capsules (OE-7) (author's transl)]. | 1976 | Jpn J Antibiot | pmid:933342 |
| Thies C | Development of injectable microcapsules for use in the treatment of narcotic addiction. | 1976 | Natl Inst Drug Abuse Res Monogr Ser | pmid:967230 |
| Gray AP and Guardina WJ | Long-acting narcotic antagonist complexes. | 1976 | Natl Inst Drug Abuse Res Monogr Ser | pmid:967231 |
| Eliasz AW et al. | Phospholipid phase transitions. Effects of n-alcohols, n-monocarboxylic acids, phenylalkyl alcohols and quaternary ammonium compounds. | 1976 | Biochim. Biophys. Acta | pmid:971432 |
| Graham KC et al. | Simple thin-layer chromatographic identification method for erythromycin stearate. | 1976 | J. Chromatogr. | pmid:977688 |
| Matsuda Y et al. | Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression. | 1976 | J Pharm Sci | pmid:978434 |
| Caster WO et al. | Effect of dietary palmitate, stearate, oleate and linoleate on the tissue lipid and systolic blood pressure of the rat. | 1976 | Int J Vitam Nutr Res | pmid:1010686 |
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| Müller WE | The use of 8-anilino-1-naphthalenesulfonic acid as a reporter group molecule for circular dichroism and fluorescence measurements. The effect of stearic acid and sodium dodecylsulfate on the conformation of bovine and human serum albumin. | 1976 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:1033907 |
| Norwitz G and Galan M | Determination of barium and strontium peroxides (active oxygen) in igniters in small-arms tracer ammunition. | 1976 | Talanta | pmid:18961958 |
| Whorton AR et al. | The metabolism of (1-14C) stearic acid in rat testicular tissue. | 1976 | Biochim. Biophys. Acta | pmid:1252481 |
| Fee JV et al. | Influence of hydrophobic materials on dissolution of a nondisintegrating hydrophilic solid (potassium chloride). | 1976 | J Pharm Sci | pmid:1255446 |
| Yamashita T et al. | [Blood concentration and urinary excretion in human of OE-7, a gastric hard capsule containing enteric-coated granules. I (author's transl)]. | 1976 | Jpn J Antibiot | pmid:1263346 |
| Agarwal HC and Nair AM | Studies on the cholesterol ester hydrolase of Trogoderma (Coleoptera). | 1976 | Biochem. J. | pmid:962852 |
| Thompson W and MacDonald G | Cytidine diphosphate diglyceride of bovine brain. Positional distribution of fatty acids and analysis of major molecular species. | 1976 | Eur. J. Biochem. | pmid:776622 |
| Warhurst DC et al. | The chemotherapy of rodent malaria, XXIV. The blood schizontocidal action of erythromycin upon Plasmodium berghei. | 1976 | Ann Trop Med Parasitol | pmid:788656 |
| Boggiano BG and Gleeson M | Gastric acid inactivation of erythromycin stearate in solid dosage forms. | 1976 | J Pharm Sci | pmid:5588 |
| Ahmed M and Enever RP | Influence of magnesium stearate on the dissolution and biological availability of sulphadiazine tablet formulations [proceedings]. | 1976 | J. Pharm. Pharmacol. | pmid:12326 |
| Sabbah A | [Letter: Immunodepressive action of erythromycin ethyl-succinate and erythromycin stearate. Study by the lymphoblastic transformation test and natural and rheumatoid rosette test]. | 1976 | Nouv Presse Med | pmid:1264643 |
| Lundberg B | Thermal properties of systems containing cholesteryl esters and triglycerides. | 1976 | Acta Chem. Scand., B, Org. Chem. Biochem. | pmid:1266525 |
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| Soler-Argilaga C et al. | The effect of sex on the quantity and properties of the very low density lipoprotein secreted by the liver in vitro. | 1976 | J. Lipid Res. | pmid:178815 |
| Uyesaka N et al. | Lanthanum and some other cation-induced changes in fluidity of synaptosomal membrane studied with nitroxide stearate spin labels. | 1976 | J. Membr. Biol. | pmid:181579 |
| Miller RW and De La Roche IA | Properties of spin labelled membranes of Fusarium oxysporum f. sp. lycopersici. | 1976 | Biochim. Biophys. Acta | pmid:182261 |
| Ruf HH and Gratzl M | Binding of nitroxide stearate spin labels to bovine serum albumin. | 1976 | Biochim. Biophys. Acta | pmid:184832 |
| Todorow S and Elies W | [Oily contrast medium in liquor space following myelography. A clinical-radiological study on extent, velocity and ways of elimination of monoiodine stearate]. | 1976 | Neurochirurgia (Stuttg) | pmid:185538 |
| Marai L et al. | Identification of isomeric doxyl stearic acids by gas-liquid chromatography and mass spectrometry. | 1976 | Chem. Phys. Lipids | pmid:186203 |
| Zenser TV et al. | Spin-labeled stearates as probes for microenvironment of murine thymocyte adenylate cyclase-cyclic adenosine 3':5'-monophosphate system. | 1976 | J. Biol. Chem. | pmid:187588 |
| Moës A | [Influence of the addition of aluminium stearate and of colloidal silica on the properties of rectal suppositories formulations (author's transl)]. | 1976 Jul-Aug | J Pharm Belg | pmid:185351 |
| Nadkarni MS et al. | Treatment of acute bacterial infections of the upper respiratory tract. | 1977 | Curr Med Res Opin | pmid:326492 |
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| Giacobino JP and Chmelar M | The role of chain elongation systems in the supplying of fatty acids to the adipocyte membrane lipids. | 1977 | Biochim. Biophys. Acta | pmid:861235 |
| Sixsmith D | The properties of tablets containing microcrystalline cellulose. | 1977 | J. Pharm. Pharmacol. | pmid:15069 |
| Newton JM and Razzo FN | The in vitro bioavailability of various drugs formulated as hard gelatin capsules. | 1977 | J. Pharm. Pharmacol. | pmid:17668 |
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| Uyesaka N | Lanthanum and some other cation-induced changes in fluidity of synaptosomal membrane studied with nitroxide stearate spin labels. J. Membrane Biol. 27:283. | 1977 | J. Membr. Biol. | pmid:190405 |