stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
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What genes are associated with stearic acid?
Related references are published most in these journals:
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Anderson EK et al. | Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. | 2012 | Arterioscler. Thromb. Vasc. Biol. | pmid:22556332 |
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| Vinay KB et al. | Spectrophotometric Determination of Mycophenolate Mofetil as Its Charge-Transfer Complexes with Two π-Acceptors. | 2012 | J Anal Methods Chem | pmid:22567572 |
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| de Souza Monteiro A et al. | Bioconversion of biodiesel refinery waste in the bioemulsifier by Trichosporon mycotoxinivorans CLA2. | 2012 | Biotechnol Biofuels | pmid:22559210 |
| Samanta AK et al. | Cone milling of compacted flakes: process parameter selection by adopting the minimal fines approach. | 2012 | Int J Pharm | pmid:22001841 |
| Tay T et al. | Dissolution of a poorly water-soluble drug dry coated with magnesium and sodium stearate. | 2012 | Eur J Pharm Biopharm | pmid:22036990 |
| Abe H and Otsuka M | Effects of lubricant-mixing time on prolongation of dissolution time and its prediction by measuring near infrared spectra from tablets. | 2012 | Drug Dev Ind Pharm | pmid:21954869 |
| Zanon NC et al. | Immbolization of uricase enzyme in Langmuir and Langmuir-Blodgett films of fatty acids: possible use as a uric acid sensor. | 2012 | J Colloid Interface Sci | pmid:21875709 |
| Walash MI et al. | Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. | 2012 | Chem Cent J | pmid:22333299 |
| Darwish IA et al. | Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate. | 2012 | Chem Cent J | pmid:22305461 |
| Schaab M et al. | Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action. | 2012 | PLoS ONE | pmid:22545089 |
| Gabirot M et al. | Differences in Chemical Sexual Signals May Promote Reproductive Isolation and Cryptic Speciation between Iberian Wall Lizard Populations. | 2012 | Int J Evol Biol | pmid:22288019 |
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| Becker S et al. | Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity. | 2012 | Cancer Biother. Radiopharm. | pmid:22149684 |
| Stryjecki C et al. | Enzymatic activity and genetic variation in SCD1 modulate the relationship between fatty acids and inflammation. | 2012 | Mol. Genet. Metab. | pmid:22209225 |
| Wei CC and Ge ZQ | Influence of electrolyte and poloxamer 188 on the aggregation kinetics of solid lipid nanoparticles (SLNs). | 2012 | Drug Dev Ind Pharm | pmid:22181005 |
| Hao J et al. | Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. | 2012 | Eur J Pharm Sci | pmid:22820033 |
| Han K et al. | Novel gene transfer vectors based on artificial recombinant multi-functional oligopeptides. | 2012 | Int J Pharm | pmid:22796172 |
| Sharma A and Chauhan RS | In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. | 2012 | Comp. Funct. Genomics | pmid:22312320 |
| Yee JK et al. | Subcutaneous adipose tissue fatty acid desaturation in adults with and without rare adipose disorders. | 2012 | Lipids Health Dis | pmid:22300160 |
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| Choi du H et al. | A new experimental design method to optimize formulations focusing on a lubricant for hydrophilic matrix tablets. | 2012 | Drug Dev Ind Pharm | pmid:22348254 |
| de Bari O et al. | Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic Fatty liver disease. | 2012 | J Lipids | pmid:22132342 |
| Kim DH et al. | Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function. | 2012 | Colloids Surf B Biointerfaces | pmid:22361356 |
| Honkanen AM et al. | Characterization of the disappearance and formation of biohydrogenation intermediates during incubations of linoleic acid with rumen fluid in vitro. | 2012 | J. Dairy Sci. | pmid:22365221 |
| Kushner J | Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume. | 2012 | Int J Pharm | pmid:22405966 |
| Matsui H et al. | Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes. | 2012 | PLoS ONE | pmid:22413010 |
| Yavuz B et al. | An overview on dry eye treatment: approaches for cyclosporin a delivery. | 2012 | ScientificWorldJournal | pmid:22619624 |
| Bonaduce I et al. | New insights into the ageing of linseed oil paint binder: a qualitative and quantitative analytical study. | 2012 | PLoS ONE | pmid:23166642 |
| Kurotani K et al. | High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. | 2012 | Nutr Res | pmid:23084639 |
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| Muro M et al. | Molecular rearrangement in a zinc stearate Langmuir film dependent on a film preparation method studied using polarization-modulation infrared reflection absorption spectroscopy and X-ray absorption fine structure. | 2012 | J Phys Chem B | pmid:22339471 |
| Okoye P et al. | To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis. | 2012 | Drug Dev Ind Pharm | pmid:22304483 |
| Wulff-Pérez M et al. | Controlling lipolysis through steric surfactants: new insights on the controlled degradation of submicron emulsions after oral and intravenous administration. | 2012 | Int J Pharm | pmid:22209995 |
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| Simonsen ME et al. | Comparison of methods for evaluation of activity of photocatalytic films. | 2012 | Environ Sci Pollut Res Int | pmid:23054739 |
| Yuan H et al. | Preparation and evaluation of SiO2-deposited stearic acid-g-chitosan nanoparticles for doxorubicin delivery. | 2012 | Int J Nanomedicine | pmid:23055724 |
| Nesarikar VV et al. | Instrumented roll technology for the design space development of roller compaction process. | 2012 | Int J Pharm | pmid:22286023 |
| Xie J et al. | Composition of fatty oils from semen ziziphi spinosae and its cardiotonic effect on isolated toad hearts. | 2012 | Nat. Prod. Res. | pmid:21707231 |
| Guo C et al. | In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. | 2012 | J Nanosci Nanotechnol | pmid:22523972 |
| Slobodkina GB et al. | Deferrisoma camini gen. nov., sp. nov., a moderately thermophilic, dissimilatory iron(III)-reducing bacterium from a deep-sea hydrothermal vent that forms a distinct phylogenetic branch in the Deltaproteobacteria. | 2012 | Int. J. Syst. Evol. Microbiol. | pmid:22140176 |
| Shah KU and Khan GM | Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. | 2012 | ScientificWorldJournal | pmid:22649325 |
| Polizzotti BD et al. | Intrapericardial delivery of gelfoam enables the targeted delivery of Periostin peptide after myocardial infarction by inducing fibrin clot formation. | 2012 | PLoS ONE | pmid:22590609 |
| Song IS et al. | Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. | 2012 | PLoS ONE | pmid:22590580 |
| Ahmed TA et al. | Miconazole nitrate oral disintegrating tablets: in vivo performance and stability study. | 2012 | AAPS PharmSciTech | pmid:22585373 |
| Varshosaz J et al. | Development and evaluation of a novel pellet-based tablet system for potential colon delivery of budesonide. | 2012 | J Drug Deliv | pmid:22577558 |