stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Alvarez-Ortega R et al. | Characterization of polar and nonpolar seed lipid classes from highly saturated fatty acid sunflower mutants. | 1997 | Lipids | pmid:9270974 |
Sparks JD et al. | Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells. | 1997 | Biochim. Biophys. Acta | pmid:9233686 |
Khomutov GB et al. | Interaction of copper ions with stearic acid Langmuir monolayers and formation of cluster structures in monolayers and Langmuir-Blodgett films. | 1997 | Membr Cell Biol | pmid:9231365 |
Yamamoto A and Kawashima Y | Perfluorodecanoic acid enhances the formation of oleic acid in rat liver. | 1997 | Biochem. J. | pmid:9230124 |
Dhillon HS et al. | Time course of changes in lactate and free fatty acids after experimental brain injury and relationship to morphologic damage. | 1997 | Exp. Neurol. | pmid:9225757 |
Noker PE et al. | Metabolism of 14C-labelled sucrose esters of stearic acid in rats. | 1997 | Food Chem. Toxicol. | pmid:9225017 |
Clandinin MT et al. | Omega-3 fatty acid intake results in a relationship between the fatty acid composition of LDL cholesterol ester and LDL cholesterol content in humans. | 1997 | Biochim. Biophys. Acta | pmid:9219909 |
Williams JP et al. | Regulation of osteoclastic bone resorption by glucose. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9207213 |
Hassel CA et al. | Dietary stearic acid reduces plasma and hepatic cholesterol concentrations without increasing bile acid excretion in cholesterol-fed hamsters. | 1997 | J. Nutr. | pmid:9187629 |
Fellner V et al. | Effect of nigericin, monensin, and tetronasin on biohydrogenation in continuous flow-through ruminal fermenters. | 1997 | J. Dairy Sci. | pmid:9178132 |