stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Tenosynovitis D013717 3 associated lipids
Infertility D007246 3 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Calculi D002137 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Yaws D015001 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Chancroid D002602 4 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Anderson EK et al. Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. 2012 Arterioscler. Thromb. Vasc. Biol. pmid:22556332
Prashanth KN and Basavaiah K Sensitive spectrophotometric determination of atenolol in pharmaceutical formulations using bromate-bromide mixture as an eco-friendly brominating agent. 2012 J Anal Methods Chem pmid:22567567
de Souza Monteiro A et al. Bioconversion of biodiesel refinery waste in the bioemulsifier by Trichosporon mycotoxinivorans CLA2. 2012 Biotechnol Biofuels pmid:22559210
Yang P et al. Transcriptome analysis of the Chinese white wax scale Ericerus pela with focus on genes involved in wax biosynthesis. 2012 PLoS ONE pmid:22536429
Nagpal M et al. Formulation development and evaluation of alginate microspheres of Ibuprofen. 2012 J Young Pharm pmid:22523454
Vijay J et al. Formulation and Evaluation of Cephalexin Extended-release Matrix Tablets Using Hydroxy Propyl Methyl Cellulose as Rate-controlling Polymer. 2012 J Young Pharm pmid:22523453
Baratta F et al. Diffusion of counterfeit drugs in developing countries and stability of galenics stored for months under different conditions of temperature and relative humidity. 2012 Croat. Med. J. pmid:22522996
Kwon Y et al. Arabidopsis serine decarboxylase mutants implicate the roles of ethanolamine in plant growth and development. 2012 Int J Mol Sci pmid:22489147
Quintela M et al. Estimation of the uncertainty associated with the results based on the validation of chromatographic analysis procedures: application to the determination of chlorides by high performance liquid chromatography and of fatty acids by high resolution gas chromatography. 2012 J Chromatogr A pmid:22227361
Schaab M et al. Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action. 2012 PLoS ONE pmid:22545089
Gabirot M et al. Differences in Chemical Sexual Signals May Promote Reproductive Isolation and Cryptic Speciation between Iberian Wall Lizard Populations. 2012 Int J Evol Biol pmid:22288019
Ghadiri M et al. Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size. 2012 Int J Pharm pmid:22227603
Kim S et al. Lipid-binding properties of TRIM72. 2012 BMB Rep pmid:22281009
Borbon IA et al. Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1. 2012 Pharmacol. Biochem. Behav. pmid:22202649
El-Enany NM et al. Development and validation of a repharsed phase- HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma. 2012 Chem Cent J pmid:22277722
Scalia S et al. Preparation and in vitro evaluation of salbutamol-loaded lipid microparticles for sustained release pulmonary therapy. 2012 J Microencapsul pmid:22208706
Anton N et al. A new application of lipid nanoemulsions as coating agent, providing zero-order hydrophilic drug release from tablets. 2012 J Drug Deliv pmid:22272376
Duong CT and Roper MG A microfluidic device for the automated derivatization of free fatty acids to fatty acid methyl esters. 2012 Analyst pmid:22166918
Zhen Z and Xie J Development of manganese-based nanoparticles as contrast probes for magnetic resonance imaging. 2012 Theranostics pmid:22272218
Imae R et al. LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice. 2012 J. Lipid Res. pmid:22172515
Becker S et al. Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity. 2012 Cancer Biother. Radiopharm. pmid:22149684
Streit MR et al. High survival in young patients using a second generation uncemented total hip replacement. 2012 Int Orthop pmid:22113735
Pijls BG et al. Polyethylene thickness is a risk factor for wear necessitating insert exchange. 2012 Int Orthop pmid:22105569
Chapple IL et al. Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double-blind RCT. 2012 J. Clin. Periodontol. pmid:22093005
Imarisio C et al. Adenosine A(2a) receptor stimulation prevents hepatocyte lipotoxicity and non-alcoholic steatohepatitis (NASH) in rats. 2012 Clin. Sci. pmid:22439844
Rojas J and Kumar V Effect of silicification on the tableting performance of cellulose ii: a novel multifunctional excipient. 2012 Chem. Pharm. Bull. pmid:22689398
Griffith EC et al. Hydrophobic collapse of a stearic acid film by adsorbed l-phenylalanine at the air-water interface. 2012 J Phys Chem B pmid:22691061
Harvey KA et al. Trans fatty acids: induction of a pro-inflammatory phenotype in endothelial cells. 2012 Lipids pmid:22684911
Mekhail GM et al. Anticancer effect of atorvastatin nanostructured polymeric micelles based on stearyl-grafted chitosan. 2012 Int. J. Biol. Macromol. pmid:22652220
Feugmo CG et al. Towards modelling the vibrational signatures of functionalized surfaces: carboxylic acids on H-Si(111) surfaces. 2012 J Phys Condens Matter pmid:22394578
Watanabe Y et al. The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation. 2012 Diabetes pmid:22396206
Choi du H et al. A new experimental design method to optimize formulations focusing on a lubricant for hydrophilic matrix tablets. 2012 Drug Dev Ind Pharm pmid:22348254
Kang JH et al. Effects of solid carriers on the crystalline properties, dissolution and bioavailability of flurbiprofen in solid self-nanoemulsifying drug delivery system (solid SNEDDS). 2012 Eur J Pharm Biopharm pmid:22119666
Schreiber R et al. Retinyl ester hydrolases and their roles in vitamin A homeostasis. 2012 Biochim. Biophys. Acta pmid:21586336
Bonaduce I et al. New insights into the ageing of linseed oil paint binder: a qualitative and quantitative analytical study. 2012 PLoS ONE pmid:23166642
Kurotani K et al. High levels of stearic acid, palmitoleic acid, and dihomo-γ-linolenic acid and low levels of linoleic acid in serum cholesterol ester are associated with high insulin resistance. 2012 Nutr Res pmid:23084639
Simmons DM and Gierer DS A material sparing test to predict punch sticking during formulation development. 2012 Drug Dev Ind Pharm pmid:22181042
Niu J et al. Octreotide-modified and pH-triggering polymeric micelles loaded with doxorubicin for tumor targeting delivery. 2012 Eur J Pharm Sci pmid:22119655
Jung HA and Augsburger LL Application of a novel automatic disintegration apparatus for the development and evaluation of a direct compression rapidly disintegrating tablet. 2012 Drug Dev Ind Pharm pmid:22091970
Aissa I et al. Synthesis of lipophilic tyrosyl esters derivatives and assessment of their antimicrobial and antileishmania activities. 2012 Lipids Health Dis pmid:22264330
Wang Z et al. Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling. 2012 Br. J. Nutr. pmid:21733316
Masuda M et al. Activating transcription factor 4 regulates stearate-induced vascular calcification. 2012 J. Lipid Res. pmid:22628618
Toubiana D et al. Metabolic profiling of a mapping population exposes new insights in the regulation of seed metabolism and seed, fruit, and plant relations. 2012 PLoS Genet. pmid:22479206
Slobodkina GB et al. Deferrisoma camini gen. nov., sp. nov., a moderately thermophilic, dissimilatory iron(III)-reducing bacterium from a deep-sea hydrothermal vent that forms a distinct phylogenetic branch in the Deltaproteobacteria. 2012 Int. J. Syst. Evol. Microbiol. pmid:22140176
Lalloo AK et al. Decoupling the role of image size and calorie intake on gastric retention of swelling-based gastric retentive formulations: pre-screening in the dog model. 2012 Int J Pharm pmid:22546295
Chakradhar RP and Dinesh Kumar V Water-repellent coatings prepared by modification of ZnO nanoparticles. 2012 Spectrochim Acta A Mol Biomol Spectrosc pmid:22575349
Agostini F et al. Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. 2012 ScientificWorldJournal pmid:22593706
Guillon A et al. Pulmonary delivery of dry powders to rats: tolerability limits of an intra-tracheal administration model. 2012 Int J Pharm pmid:22609125
Schrank S et al. Ibuprofen-loaded calcium stearate pellets: drying-induced variations in dosage form properties. 2012 AAPS PharmSciTech pmid:22552931
Loutelier-Bourhis C et al. Mechanistic study of maleic anhydride grafting onto fatty double bonds using mass spectrometry. 2012 Rapid Commun. Mass Spectrom. pmid:22555920