stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Eczema, Dyshidrotic D011146 1 associated lipids
Decalcification, Pathologic D003649 1 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Infertility D007246 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Chancroid D002602 4 associated lipids
Yaws D015001 4 associated lipids
Foreign Bodies D005547 5 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Thiel WJ and Sberna FJ Fluidized bed film coating of an interactive powder mixture to produce microencapsulated 2-5 microns particles. 1986 J. Pharm. Pharmacol. pmid:2871149
Hattori T et al. Attenuation by pentobarbital of free fatty acid and diacylglycerol liberation during global ischaemia in rat brain. 1986 Neurol. Res. pmid:2871507
Catalá A Stearic acid desaturation in rat liver microsomes: stimulation by fatty acid binding protein. 1986 Acta Physiol Pharmacol Latinoam pmid:2876583
Gotoh K et al. Effects of unsaturated fatty acids on the peroxisomal enzyme activities of Tetrahymena pyriformis. 1986 J. Biochem. pmid:2880840
Crosby T et al. Identification of ecdysone 22-long-chain fatty acyl esters in newly laid eggs of the cattle tick Boophilus microplus. 1986 Biochem. J. pmid:3030275
Reddy TS et al. Fatty acid composition and arachidonic acid metabolism in vitreous lipids from canine and human eyes. 1986 Curr. Eye Res. pmid:3089690
Dudley DT and Spector AA Inositol phospholipid arachidonic acid metabolism in GH3 pituitary cells. 1986 Biochem. J. pmid:3098231
Chowhan ZT and Chi LH Drug-excipient interactions resulting from powder mixing. III: Solid state properties and their effect on drug dissolution. 1986 J Pharm Sci pmid:3735096
Chowhan ZT and Chi LH Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution. 1986 J Pharm Sci pmid:3735097
Fujii T et al. Effect of exogenous lipids incorporated into the membrane of human erythrocytes on its glucose transport activity. 1986 Biochem. Int. pmid:3741447
Chester DW et al. The influence of saturated fatty acid modulation of bilayer physical state on cellular and membrane structure and function. 1986 Biochim. Biophys. Acta pmid:3741857
Tsao FH Selective use of palmitic acid over stearic acid for synthesis of phosphatidylcholine and phosphatidylglycerol in lung. 1986 Lipids pmid:3796238
Ito Y et al. Fatty acid synthetase as a thermoreceptor in Candida utilis. 1986 J. Biochem. pmid:3745143
Muralidharan FN and Muralidharan VB Phytanoyl-CoA ligase activity in rat liver. 1986 Biochem. Int. pmid:3753503
Ball MD et al. Acyl coenzyme A:retinol acyltransferase activity and the vitamin A content of polar bear (Ursus maritimus) liver. 1986 Comp. Biochem. Physiol., B pmid:3757481
van den Reek MM et al. Use of published analyses of food items to determine dietary trans octadecenoic acid. 1986 J Am Diet Assoc pmid:3760430
Sugimoto Y et al. A 2H NMR study on alteration of the membrane organization of mouse B16 melanoma cells treated with 12-O-tetradecanoylphorbol-13-acetate. 1986 J. Biochem. pmid:3818567
Thompson W and Belina H Rapid accumulation of diacyl lipid in rat liver microsomes by selective acylation of 2-acyl-sn-glycero-3-phosphorylserine. 1986 Biochim. Biophys. Acta pmid:3707975
Heape AM et al. Technique for injection into the sciatic nerve of the mouse for quantitative in vivo metabolic studies. 1986 Anal. Biochem. pmid:3717558
Caponnetto A et al. [Correlations between unsaturated fatty acids and medium C-chain triglycerides]. 1986 Boll. Soc. Ital. Biol. Sper. pmid:3718739
Beaumelle BD and Vial HJ Modification of the fatty acid composition of individual phospholipids and neutral lipids after infection of the simian erythrocyte by Plasmodium knowlesi. 1986 Biochim. Biophys. Acta pmid:3719005
Pajor L et al. Microsomal desaturation of stearic acid in relation to lymphocyte activation. 1986 Arch. Biochem. Biophys. pmid:3485399
Ras GJ and Anderson R An in-vitro study of oral therapeutic doses of co-trimoxazole and erythromycin stearate on abnormal polymorphonuclear leucocyte migration. 1986 J. Antimicrob. Chemother. pmid:3486178
Muñoz-Espin T et al. Erythromycin versus tetracycline for treatment of Mediterranean spotted fever. 1986 Arch. Dis. Child. pmid:3535687
Bankson DD et al. Determination of retinyl esters and retinol in serum or plasma by normal-phase liquid chromatography: method and applications. 1986 Clin. Chem. pmid:3940733
Yamamoto O Radiation-induced crosslinks between carboxylic acids and compounds of biological interest. 1986 Radiat. Res. pmid:3952268
Villa P et al. Effects of a new fluorinated macrolide (P-0501A) and other erythromycins on drug metabolizing enzymes in rat liver. 1986 J. Antibiot. pmid:3084433
Okabe H et al. Effects of anti-convulsants on fatty acid metabolism in human serum. 1986 Tohoku J. Exp. Med. pmid:3705068
Siegel I et al. Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. 1986 Fertil. Steril. pmid:2868925
Johansson ME and Nicklasson M Investigation of the film formation of magnesium stearate by applying a flow-through dissolution technique. 1986 J. Pharm. Pharmacol. pmid:2869127
Tabachnick M and Korcek L Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. 1986 Biochim. Biophys. Acta pmid:2869786
Alcalay J et al. Asymptomatic liver injury due to erythromycin stearate. 1986 Jul-Aug Drug Intell Clin Pharm pmid:3743417
Goto S et al. Eudragit RS and RL (acrylic resins) microcapsules as pH insensitive and sustained release preparations of ketoprofen. 1986 Oct-Dec J Microencapsul pmid:3508190
Goto S et al. Eudragit E, L and S (acrylic resins) microcapsules as pH sensitive release preparations of ketoprofen. 1986 Oct-Dec J Microencapsul pmid:3508191
Adebayo GI et al. Time-dependent inhibition of theophylline elimination by erythromycin stearate. 1986 Sep-Oct Biopharm Drug Dispos pmid:3779037
Bergquist SO et al. Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. 1987 Pediatr. Infect. Dis. J. pmid:2885802
Zara GP et al. Erythromycin and gastrointestinal motility. 1987 Lancet pmid:2889954
Roughan PG et al. Metabolism of exogenous long-chain fatty acids by spinach leaves. 1987 Arch. Biochem. Biophys. pmid:3426240
Habib NA et al. Stearic acid and carcinogenesis. 1987 Br. J. Cancer pmid:3689663
Kaya K and Nohara K Effect of di-n-octyl phthalate on fatty acid composition of phosphatidylcholine in Tetrahymena. 1987 Chem. Biol. Interact. pmid:3690725
Berlin E et al. Influence of saturated and unsaturated fats on platelet fatty acids in cholesterol-fed rabbits. 1987 Atherosclerosis pmid:3827974
Cutler RR et al. The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. 1987 Tubercle pmid:3448797
Matsui MS and Jeffrey AM Fatty acid modification of C3H 10T 1/2 fibroblast cells: changes in benzo(a)pyrene metabolism and phorbol ester binding. 1987 Cancer Res. pmid:3471326
Habib NA et al. Desaturation-producing factor present in the tissue, blood, and urine of cancer patients. 1987 Cancer Detect. Prev. pmid:3568009
Wang ST et al. A comparison of fatty acid composition of cholesteryl esters in subjects at various concentrations of serum lipid. 1987 Clin. Biochem. pmid:3568345
Pospísilová B and Kubes J [Stability of erythromycin stearate in coated tablets during the action of gastric juice in vitro]. 1987 Cesk Farm pmid:3581192
Worman CP et al. Saturation index of blood cell membrane fatty acids before and after IFN treatment in hairy cell leukemia. 1987 Leukemia pmid:3669764
Caglayan S et al. Is medical therapy effective for regional lymphadenitis following BCG vaccination? 1987 Am. J. Dis. Child. pmid:3673975
Hattori T et al. Membrane phospholipid composition and membrane fluidity of human brain tumour: a spin label study. 1987 Neurol. Res. pmid:2883605
Søreide O et al. Inadequacy of oleic acid in erythrocytes as a marker of malignancies. 1987 Br Med J (Clin Res Ed) pmid:3103770