| MeSH term | MeSH ID | Detail |
|---|---|---|
| Decalcification, Pathologic | D003649 | 1 associated lipids |
| Eczema, Dyshidrotic | D011146 | 1 associated lipids |
| Salivary Duct Calculi | D012465 | 2 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Relapsing Fever | D012061 | 3 associated lipids |
| Tenosynovitis | D013717 | 3 associated lipids |
| Infertility | D007246 | 3 associated lipids |
| Obesity, Abdominal | D056128 | 3 associated lipids |
| Hypothalamic Diseases | D007027 | 3 associated lipids |
| Syphilis, Congenital | D013590 | 3 associated lipids |
| Pneumoconiosis | D011009 | 3 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Calculi | D002137 | 3 associated lipids |
| Yaws | D015001 | 4 associated lipids |
| Leukodystrophy, Metachromatic | D007966 | 4 associated lipids |
| Syphilis, Latent | D013592 | 4 associated lipids |
| Prostatic Diseases | D011469 | 4 associated lipids |
| Legionnaires' Disease | D007877 | 4 associated lipids |
| Chancroid | D002602 | 4 associated lipids |
| Boutonneuse Fever | D001907 | 5 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sun GY | Metabolism of arachidonate and stearate injected simultaneously into the mouse brain. | 1977 | Lipids | pmid:895416 |
| Awad AB et al. | The effect of unsaturated fatty acids on membrane composition and signal transduction in HT-29 human colon cancer cells. | 1996 | Cancer Lett. | pmid:8950205 |
| Kankofer M et al. | The analysis of fatty acid content and phospholipase A2 activity in placenta of cows with and without retained fetal membranes. | 1996 | Zentralbl Veterinarmed A | pmid:8940891 |
| Kole HK et al. | A synthetic peptide derived from a COOH-terminal domain of the insulin receptor specifically enhances insulin receptor signaling. | 1996 | J. Biol. Chem. | pmid:8940181 |
| Peck MD et al. | Association of murine splenocyte CD3 complex to the cytoskeleton: absence of modulation by exogenous fatty acids. | 1996 | Cell Biol. Int. | pmid:8938986 |
| Halliwell KJ et al. | Release of individual fatty acids from human adipose tissue in vivo after an overnight fast. | 1996 | J. Lipid Res. | pmid:8895050 |
| Peck MD et al. | Fatty acid unsaturation increases expression and capping of murine lymphocyte CD44 and CD45. | 1996 | Nutrition | pmid:8878171 |
| Wargo DJ and Drennen JK | Near-infrared spectroscopic characterization of pharmaceutical powder blends. | 1996 | J Pharm Biomed Anal | pmid:8877847 |
| Murkovic M et al. | Variability of fatty acid content in pumpkin seeds (Cucurbita pepo L.). | 1996 | Z Lebensm Unters Forsch | pmid:8873459 |
| Uchida T et al. | Microencapsulation of ovalbumin in poly(lactide-co-glycolide) by an oil-in-oil (o/o) solvent evaporation method. | 1996 Sep-Oct | J Microencapsul | pmid:8864988 |
| Shetty HU et al. | Identification of two molecular species of rat brain phosphatidylcholine that rapidly incorporate and turn over arachidonic acid in vivo. | 1996 | J. Neurochem. | pmid:8858956 |
| Gotoh N et al. | Inhibition of oxidation of low density lipoprotein by vitamin E and related compounds. | 1996 | Free Radic. Res. | pmid:8845913 |
| Pai T and Yeh YY | Stearic acid unlike shorter-chain saturated fatty acids is poorly utilized for triacylglycerol synthesis and beta-oxidation in cultured rat hepatocytes. | 1996 | Lipids | pmid:8835403 |
| Kirsch AJ et al. | Effects of diode laser welding with dye-enhanced glue on tensile strength of sutures commonly used in urology. | 1996 | Lasers Surg Med | pmid:8833285 |
| Reverey H et al. | Differential fatty acid selection during biosynthetic S-acylation of a transmembrane protein (HEF) and other proteins in insect cells (Sf9) and in mammalian cells (CV1). | 1996 | J. Biol. Chem. | pmid:8798573 |
| Mastronicolis SK et al. | Diversity of the polar lipids of the food-borne pathogen Listeria monocytogenes. | 1996 | Lipids | pmid:8784744 |
| Negash S et al. | Phosphorylation of phospholamban by cAMP-dependent protein kinase enhances interactions between Ca-ATPase polypeptide chains in cardiac sarcoplasmic reticulum membranes. | 1996 | Biochemistry | pmid:8784178 |
| Hughes TA et al. | Comparative lipoprotein metabolism of myristate, palmitate, and stearate in normolipidemic men. | 1996 | Metab. Clin. Exp. | pmid:8781298 |
| Zakhariv OIa and Ianovich VG | [The utilization of [9,10-(3)H] stearic and [1-(14)C] linolenic acids in the in-vitro synthesis of lipids in ruminant tissues]. | 1995 Jul-Aug | Zh. Evol. Biokhim. Fiziol. | pmid:8779280 |
| Schmidt-Weber CB et al. | Apoptotic cell death in activated monocytes following incorporation of clodronate-liposomes. | 1996 | J. Leukoc. Biol. | pmid:8773585 |
| Veit M et al. | Cytoplasmic tail length influences fatty acid selection for acylation of viral glycoproteins. | 1996 | Biochem. J. | pmid:8761467 |
| Mansbach CM | The origin of chylomicron phosphatidylcholine in the rat. | 1977 | J. Clin. Invest. | pmid:874099 |
| Shu R et al. | [Chemical constituents of Cyclocarya paliurus (Batal.) Iljinsk]. | 1995 | Zhongguo Zhong Yao Za Zhi | pmid:8737472 |
| Xiong W et al. | [Hydrothobic constituents of Nyssa sinensis Oliv]. | 1995 | Zhongguo Zhong Yao Za Zhi | pmid:8737471 |
| Britten JR et al. | Studies on powder plug formation using a simulated capsule filling machine. | 1996 | J. Pharm. Pharmacol. | pmid:8737048 |
| Sherrington EJ et al. | Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736816 |
| Lassus A et al. | Erythromycin and lymecycline treatment in chlamydia-positive and Chlamydia-negative non-gonococcal urethritis--a partner-controlled study. | 1979 | Acta Derm. Venereol. | pmid:87096 |
| Sakai M et al. | Pharmacological effects of phosphatidylserine enzymatically synthesized from soybean lecithin on brain functions in rodents. | 1996 | J. Nutr. Sci. Vitaminol. | pmid:8708821 |
| Watts GF et al. | Dietary fatty acids and progression of coronary artery disease in men. | 1996 | Am. J. Clin. Nutr. | pmid:8694021 |
| Tholstrup T et al. | Acute effect of high-fat meals rich in either stearic or myristic acid on hemostatic factors in healthy young men. | 1996 | Am. J. Clin. Nutr. | pmid:8694016 |
| van Greevenbroek MM et al. | Effects of saturated, mono-, and polyunsaturated fatty acids on the secretion of apo B containing lipoproteins by Caco-2 cells. | 1996 | Atherosclerosis | pmid:8678919 |
| Bruce JS and Salter AM | Metabolic fate of oleic acid, palmitic acid and stearic acid in cultured hamster hepatocytes. | 1996 | Biochem. J. | pmid:8670161 |
| Ohyama H et al. | Age-related differences in synaptosomal membrane fluidity. | 1995 | Biochem. Mol. Biol. Int. | pmid:8653075 |
| Narayanan VS and Storch J | Fatty acid transfer in taurodeoxycholate mixed micelles. | 1996 | Biochemistry | pmid:8652524 |
| Cheng B et al. | Characterization and identification of an adrenal age-related nonpolar fluorescent substance. | 1996 | Endocrinology | pmid:8641198 |
| Rich MR and Evans JS | Molecular dynamics simulations of adipocyte lipid-binding protein: effect of electrostatics and acyl chain unsaturation. | 1996 | Biochemistry | pmid:8634281 |
| Carratù L et al. | Membrane lipid perturbation modifies the set point of the temperature of heat shock response in yeast. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8632982 |
| Watanabe S and Sato T | Effects of free fatty acids on the binding of bovine and human serum albumin with steroid hormones. | 1996 | Biochim. Biophys. Acta | pmid:8620023 |
| Giacobino JP and Chmelar M | The role of chain elongation systems in the supplying of fatty acids to the adipocyte membrane lipids. | 1977 | Biochim. Biophys. Acta | pmid:861235 |
| Wisniewska A et al. | Depth dependence of the perturbing effect of placing a bulky group (oxazolidine ring spin labels) in the membrane on the membrane phase transition. | 1996 | Biochim. Biophys. Acta | pmid:8611609 |
| Ntambi JM et al. | A model cell line to study regulation of stearoyl-CoA desaturase gene 1 expression by insulin and polyunsaturated fatty acids. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8607881 |
| Pearson TA and Kris-Etherton PM | Effects of diets containing high or low amounts of stearic acid on plasma lipoprotein fractions and fecal fatty acid excretion of men. | 1996 | Am. J. Clin. Nutr. | pmid:8602600 |
| Routi T et al. | Effects of prospective, randomized cholesterol-lowering dietary intervention and apolipoprotein E phenotype on serum lipoprotein(a) concentrations of infants aged 7-24 mo. | 1996 | Am. J. Clin. Nutr. | pmid:8602597 |
| Blaha CD et al. | Improved electrochemical properties of stearate-graphite paste electrodes after albumin and phospholipid treatments. | 1996 | Biosens Bioelectron | pmid:8600916 |
| Schwab US et al. | Different effects of palmitic and stearic acid-enriched diets on serum lipids and lipoproteins and plasma cholesteryl ester transfer protein activity in healthy young women. | 1996 | Metab. Clin. Exp. | pmid:8596480 |
| Lin HH et al. | Increased norfloxacin skin permeability for fatty alcohol propylene glycol (FAPG) ointment by optimized process of preparation: behavior of stearic acid in stratum corneum lipids. | 1995 | Biol. Pharm. Bull. | pmid:8593480 |
| Singh S et al. | Multiple emulsion-based systems carrying insulin: development and characterization. | 1995 Nov-Dec | J Microencapsul | pmid:8558383 |
| Iskhakova FKh et al. | [Synthesis of stearoyl derivatives of proline-containing hydrophobic peptides]. | 1995 | Bioorg. Khim. | pmid:8540900 |
| Cárdenas L et al. | Isolation, chemical structures and biological activity of the lipo-chitin oligosaccharide nodulation signals from Rhizobium etli. | 1995 | Plant Mol. Biol. | pmid:8534845 |
| Melik-Nubarov NS et al. | Interaction of hydrophobized antiviral antibodies with influenza virus infected MDCK cells. | 1993 | Biochem. Mol. Biol. Int. | pmid:8508145 |
| Sylvester PW et al. | Effects of specific fatty acids on prolactin-induced NB2 lymphoma cell proliferation. | 1993 | Life Sci. | pmid:8505862 |
| Sastri MS et al. | In vitro and in vivo studies on slow release propranolol hydrochloride suppositories. Pharmacokinetic and pharmacodynamic evaluation. | 1993 | Arzneimittelforschung | pmid:8489559 |
| Mustad VA et al. | Comparison of the effects of diets rich in stearic acid versus myristic acid and lauric acid on platelet fatty acids and excretion of thromboxane A2 and PGI2 metabolites in healthy young men. | 1993 | Metab. Clin. Exp. | pmid:8487669 |
| Doering TL et al. | Trypanosome metabolism of myristate, the fatty acid required for the variant surface glycoprotein membrane anchor. | 1993 | J. Biol. Chem. | pmid:8486622 |
| Woldseth B et al. | Incorporation of stearic acid (18:0) and palmitic acid (16:0) in phospholipid molecular species studied in isolated rat liver cells. | 1993 | Biochim. Biophys. Acta | pmid:8481391 |
| el-Sharkawy SH et al. | Microbiological transformations of lipids: acyl-specific hydrolysis of lard by yeasts. | 1993 | Appl. Environ. Microbiol. | pmid:8480999 |
| Michiels C et al. | Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia. | 1993 | Am. J. Physiol. | pmid:8476019 |
| Mensink RP | Effects of the individual saturated fatty acids on serum lipids and lipoprotein concentrations. | 1993 | Am. J. Clin. Nutr. | pmid:8475888 |
| Hari PR and Sharma CP | Protein adsorption--effect of external lubricants at the interface. | 1993 | J Biomater Appl | pmid:8473987 |
| Hamilton KS et al. | Glycosphingolipid backbone conformation and behavior in cholesterol-containing phospholipid bilayers. | 1993 | Biochemistry | pmid:8471610 |
| Nishihira J et al. | Identification of the hydrophobic ligand-binding region in recombinant glutathione S-transferase P and its binding effect on the conformational state of the enzyme. | 1993 | Arch. Biochem. Biophys. | pmid:8470890 |
| Muszbek L and Laposata M | Myristoylation of proteins in platelets occurs predominantly through thioester linkages. | 1993 | J. Biol. Chem. | pmid:8463334 |
| Derr J et al. | The role of fatty acid saturation on plasma lipids, lipoproteins, and apolipoproteins: II. The plasma total and low-density lipoprotein cholesterol response of individual fatty acids. | 1993 | Metab. Clin. Exp. | pmid:8446040 |
| Poulos A et al. | Fatty acid synthesis from [2-14C]acetate in normal and peroxisome-deficient (Zellweger) fibroblasts. | 1993 | Lipids | pmid:8441343 |
| Das T et al. | Characterization of cardiac fatty-acid-binding protein from human placenta. Comparison with placenta hepatic types. | 1993 | Eur. J. Biochem. | pmid:8436130 |
| Callaghan R et al. | Increased accumulation of drugs in a multidrug resistant cell line by alteration of membrane biophysical properties. | 1993 | Biochim. Biophys. Acta | pmid:8435444 |
| Baer HH and Wu X | Synthesis of alpha,alpha-trehalose 2,3- and 2,3'-diesters with palmitic and stearic acid: potential immunoreactants for the serodiagnosis of tuberculosis. | 1993 | Carbohydr. Res. | pmid:8431934 |
| Wada H et al. | In vitro ferredoxin-dependent desaturation of fatty acids in cyanobacterial thylakoid membranes. | 1993 | J. Bacteriol. | pmid:8419301 |
| Imaizumi K et al. | Fat containing stearic acid increases fecal neutral steroid excretion and catabolism of low density lipoproteins without affecting plasma cholesterol concentration in hamsters fed a cholesterol-containing diet. | 1993 | J. Nutr. | pmid:8410360 |
| Emken EA et al. | Influence of linoleic acid on desaturation and uptake of deuterium-labeled palmitic and stearic acids in humans. | 1993 | Biochim. Biophys. Acta | pmid:8399342 |
| Viswanathan R et al. | Strained-layer van der Waals epitaxy in a Langmuir-Blodgett film. | 1993 | Science | pmid:8392751 |
| Vilim A et al. | A simple thin-layer chromatographic identification procedure for erythromycin base, stearate, estolate and ethylsuccinate. | 1977 | J. Chromatogr. | pmid:838805 |
| Raines DE and Miller KW | The role of charge in lipid selectivity for the nicotinic acetylcholine receptor. | 1993 | Biophys. J. | pmid:8386010 |
| Cisar LA et al. | Interleukin-1 selectively potentiates bradykinin-stimulated arachidonic acid release from human synovial fibroblasts. | 1993 | Cell. Signal. | pmid:8373725 |
| Zock PL et al. | Effects of stearic acid and trans fatty acids versus linoleic acid on blood pressure in normotensive women and men. | 1993 | Eur J Clin Nutr | pmid:8365385 |
| Lurie E et al. | N-(2-hydroxybenzyl)-omega-amino carbonic acids and their derivatives as tools for biochemical and biophysical investigations. | 1993 | Biochem. Mol. Biol. Int. | pmid:8358340 |
| Monsma CC and Ney DM | Interrelationship of stearic acid content and triacylglycerol composition of lard, beef tallow and cocoa butter in rats. | 1993 | Lipids | pmid:8355579 |
| Muriana FJ et al. | Lipid and fatty acid composition of hepatopancreatic brush-border membrane vesicles from the prawn Penaeus japonicus. | 1993 | J. Biochem. | pmid:8340355 |
| Patil GS and Cornwell DG | Surface phase separation and collapse of the stearate anion--alkaline earth cation complex. | 1977 | J. Lipid Res. | pmid:833501 |
| Rich MR | Conformational analysis of arachidonic and related fatty acids using molecular dynamics simulations. | 1993 | Biochim. Biophys. Acta | pmid:8329458 |
| Tetzloff SU and Bizzozero OA | Proteolipid protein from the peripheral nervous system also contains covalently bound fatty acids. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8323550 |
| Larner JM et al. | The isolation and characterization of estradiol-fatty acid esters in human ovarian follicular fluid. Identification of an endogenous long-lived and potent family of estrogens. | 1993 | J. Biol. Chem. | pmid:8314757 |
| Tholstrup T et al. | Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids. | 1994 | Am. J. Clin. Nutr. | pmid:8310987 |
| Mitropoulos KA et al. | Dietary fat induces changes in factor VII coagulant activity through effects on plasma free stearic acid concentration. | 1994 | Arterioscler. Thromb. | pmid:8305411 |
| Croxtall JD et al. | Tamoxifen inhibits growth of oestrogen receptor-negative A549 cells. | 1994 | Biochem. Pharmacol. | pmid:8304964 |
| Moehren G et al. | Activation and desensitization of phospholipase D in intact rat hepatocytes. | 1994 | J. Biol. Chem. | pmid:8288637 |
| Hrelia S et al. | In vivo effect of chronic ethanol consumption on the fatty acid composition of phosphatidylinositols in resting and anti-CD3-activated lymphocytes. | 1993 | Alcohol. Clin. Exp. Res. | pmid:8279665 |
| Sullivan JL et al. | Performance of dairy cows fed short staple, Pima, and cracked Pima cottonseed and feed characteristics. | 1993 | J. Dairy Sci. | pmid:8270698 |
| Koroly MJ and Conner RL | Unsaturated fatty acid biosynthesis in Tetrahymena. Evidence for two pathways. | 1976 | J. Biol. Chem. | pmid:826532 |
| Ramanadham S et al. | Mass spectrometric characterization of arachidonate-containing plasmalogens in human pancreatic islets and in rat islet beta-cells and subcellular membranes. | 1993 | Biochemistry | pmid:8257685 |
| Visioli F et al. | Free fatty acid and diacylglycerol accumulation in the rat brain during recurrent seizures is related to cortical oxygenation. | 1993 | J. Neurochem. | pmid:8228997 |
| Samochocki M and Strosznajder J | Modulatory action of arachidonic acid on GABAA/chloride channel receptor function in adult and aged brain cortex membranes. | 1993 | Neurochem. Int. | pmid:8220171 |
| Lee WN et al. | In vivo measurement of fatty acids and cholesterol synthesis using D2O and mass isotopomer analysis. | 1994 | Am. J. Physiol. | pmid:8203508 |
| Doering TL et al. | The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols. | 1994 | Biochem. J. | pmid:8192662 |
| Batten TL et al. | Contact dermatitis from the old formula E45 cream. | 1994 | Contact Derm. | pmid:8187515 |
| Belluzzi A et al. | Short report: zinc sulphate supplementation corrects abnormal erythrocyte membrane long-chain fatty acid composition in patients with Crohn's disease. | 1994 | Aliment. Pharmacol. Ther. | pmid:8186338 |
| Lu B et al. | Characterization of modified staphylococcal protein A containing phospholipid monolayer on both solution and slide surfaces. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8185601 |
| Chigorno V et al. | Biosynthesis of gangliosides containing C18:1 and C20:1 [3-14C]sphingosine after administrating [1-14C]palmitic acid and [1-14C]stearic acid to rat cerebellar granule cells in culture. | 1994 | Eur. J. Biochem. | pmid:8181467 |
| Musty PR and Nickless G | Extractants for organochlorine insecticides and polychlorinated biphenyls from water. | 1976 | J. Chromatogr. | pmid:818099 |
| Hyson DA et al. | Differential and interactive effects of calcium channel blockers and cholesterol content of the diet on jejunal uptake of lipids in rabbits. | 1994 | Lipids | pmid:8177021 |