stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Relapsing Fever D012061 3 associated lipids
Infertility D007246 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Chancroid D002602 4 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Foreign Bodies D005547 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Zhang JW et al. [Studies on the chemical constituents of Toricellia angulata var. intermedia]. 2010 Zhong Yao Cai pmid:21434432
Chen Y et al. A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. 2010 Appl Spectrosc pmid:20925991
Mukherjee S et al. Stearic acid delivery to corneum from a mild and moisturizing cleanser. 2010 J Cosmet Dermatol pmid:20883293
Salem HF Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats. 2010 Int J Nanomedicine pmid:21187946
Daraghmeh N et al. Preparation and characterization of a novel co-processed excipient of chitin and crystalline mannitol. 2010 AAPS PharmSciTech pmid:21052880
Rawat MK et al. Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. 2010 Ther Deliv pmid:22816120
Legrand P and Rioux V The complex and important cellular and metabolic functions of saturated fatty acids. 2010 Lipids pmid:20625935
Patra S et al. In vitro evaluation of domperidone mouth dissolving tablets. 2010 Indian J Pharm Sci pmid:21969764
Akpa MM et al. Inhibition of insulin and T3-induced fatty acid synthase by hexanoate. 2010 Lipids pmid:20811782
Hodson L et al. Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation? 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20628024
Lin YK et al. Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery. 2010 Int J Nanomedicine pmid:20309398
Seerapu S and Srinivasan BP Development and Validation of RP-HPLC Method for the Estimation of Ivabradine Hydrochloride in Tablets. 2010 Indian J Pharm Sci pmid:21695008
Kharia AA et al. Design and optimization of floating drug delivery system of acyclovir. 2010 Indian J Pharm Sci pmid:21694992
Liu TY and Lin YL Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. 2010 Acta Biomater pmid:19819354
Jeevanandham S et al. Sustain-release of various drugs from leucaena leucocephala polysaccharide. 2010 J Young Pharm pmid:21331185
Kiss H et al. Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). 2010 Stand Genomic Sci pmid:21304711
Pedersen PJ et al. Liposomal formulation of retinoids designed for enzyme triggered release. 2010 J. Med. Chem. pmid:20405849
Liew CV et al. In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. 2010 Int J Pharm pmid:19922776
Harvey KA et al. Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. 2010 Clin Nutr pmid:19926177
Zhou Q et al. Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating. 2010 J Pharm Sci pmid:19795479
Uchimoto T et al. Lubrication properties of potential alternative lubricants, glycerin fatty acid esters, to magnesium stearate. 2010 Int J Pharm pmid:19913080
Muro M et al. A conformation and orientation model of the carboxylic group of fatty acids dependent on chain length in a Langmuir monolayer film studied by polarization-modulation infrared reflection absorption spectroscopy. 2010 J Phys Chem B pmid:20718412
Nouri A et al. Effect of process control agent on the porous structure and mechanical properties of a biomedical Ti-Sn-Nb alloy produced by powder metallurgy. 2010 Acta Biomater pmid:19815096
Liu RS and Tang YJ Quantitative analysis for the effect of plant oil and fatty acid on Tuber melanosporum culture by uniform design combined with partial least squares regression. 2010 Appl. Microbiol. Biotechnol. pmid:20473608
Sun H et al. Complete genome sequence of Desulfarculus baarsii type strain (2st14). 2010 Stand Genomic Sci pmid:21304732
Pennick G et al. Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. 2010 Int J Cosmet Sci pmid:20642769
Akazawa Y et al. Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis. 2010 J. Hepatol. pmid:20206402
Song HJ et al. Effect of probiotic Lactobacillus (Lacidofil® cap) for the prevention of antibiotic-associated diarrhea: a prospective, randomized, double-blind, multicenter study. 2010 J. Korean Med. Sci. pmid:21165295
Chen JL et al. Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry. 2010 World J. Gastroenterol. pmid:21155010
Kajiro H et al. Flexible two-dimensional square-grid coordination polymers: structures and functions. 2010 Int J Mol Sci pmid:21152303
Coulon C et al. Chemical analysis of cellular and extracellular carbohydrates of a biofilm-forming strain Pseudomonas aeruginosa PA14. 2010 PLoS ONE pmid:21151973
Wieder DR and Pattimakiel L Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). 2010 Int J Womens Health pmid:21151688
Karande AD et al. In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. 2010 Int J Pharm pmid:20558264
Kim IS and Oh IJ Preparation and characterization of stearic acid-pullulan nanoparticles. 2010 Arch. Pharm. Res. pmid:20512475
Wang J et al. Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. 2010 J Pharm Sci pmid:20533436
Karande AD et al. Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend. 2010 Int J Pharm pmid:20472048
Akihisa T et al. Triterpene alcohol and fatty acid composition of shea nuts from seven African countries. 2010 J Oleo Sci pmid:20513968
Kanjanavas P et al. Purification and characterization of organic solvent and detergent tolerant lipase from thermotolerant Bacillus sp. RN2. 2010 Int J Mol Sci pmid:21152301
Tripathi B and Platel K Finger millet (Eleucine coracana) flour as a vehicle for fortification with zinc. 2010 J Trace Elem Med Biol pmid:20122580
Huang WH et al. Development of liposomal salbutamol sulfate dry powder inhaler formulation. 2010 Biol. Pharm. Bull. pmid:20190418
Shishu VR et al. Development of taste masked oral formulation of ornidazole. 2010 Indian J Pharm Sci pmid:20838525
Jeong SH and Park K Simple preparation of coated resin complexes and their incorporation into fast-disintegrating tablets. 2010 Arch. Pharm. Res. pmid:20191352
Gohel MC et al. Fabrication and Evaluation of Bi-layer Tablet Containing Conventional Paracetamol and Modified Release Diclofenac Sodium. 2010 Indian J Pharm Sci pmid:20838522
Cho KH et al. Monoacylglycerol (MAG)-oleic acid has stronger antioxidant, anti-atherosclerotic, and protein glycation inhibitory activities than MAG-palmitic acid. 2010 J Med Food pmid:20136442
Phaechamud T et al. Preparation of Coated Valproic Acid and Sodium Valproate Sustained-release Matrix Tablets. 2010 Indian J Pharm Sci pmid:20838520
Yang X et al. In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. 2010 Drug Dev Ind Pharm pmid:20141448
Huthmacher C et al. Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. 2010 BMC Syst Biol pmid:20807400
Du YZ et al. Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: factors affecting the complexation. 2010 Int J Pharm pmid:20170716
Noguchi Y et al. Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice. 2010 PLoS ONE pmid:20706589
Baki G et al. Role of surface free energy and spreading coefficient in the formulation of active agent-layered pellets. 2010 Eur J Pharm Biopharm pmid:19931611
Maher AC et al. Women have higher protein content of beta-oxidation enzymes in skeletal muscle than men. 2010 PLoS ONE pmid:20700461
Bolton B and Halpern BP Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. 2010 Chem. Senses pmid:20100787
Wang Q et al. One-Step Synthesis of Monodisperse In-Doped ZnO Nanocrystals. 2010 Nanoscale Res Lett pmid:20672040
Lu L et al. Near infrared spectroscopy of stearic acid adsorbed on montmorillonite. 2010 Spectrochim Acta A Mol Biomol Spectrosc pmid:20071218
Pöllänen E et al. Power training and postmenopausal hormone therapy affect transcriptional control of specific co-regulated gene clusters in skeletal muscle. 2010 Age (Dordr) pmid:20640546
Roblegg E et al. Development of lipophilic calcium stearate pellets using ibuprofen as model drug. 2010 Eur J Pharm Biopharm pmid:20080179
Gentile CL et al. Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. 2010 Mol. Cell. Biochem. pmid:20607591
Bele MH et al. Effect of Flow Aids on Mucoadhesive Properties of Polymeric Discs of Polyoxyethylene and Carbopol 971P. 2010 Indian J Pharm Sci pmid:20582205
Rao KS and Srinivas K RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form. 2010 Indian J Pharm Sci pmid:20582199
Keny RV et al. Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. 2010 Indian J Pharm Sci pmid:20582194
Li LO et al. Early hepatic insulin resistance in mice: a metabolomics analysis. 2010 Mol. Endocrinol. pmid:20150186
Blanco M and Peguero A Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. 2010 J Pharm Biomed Anal pmid:20044229
Swanson EJ et al. Phospholipid-stabilized microbubble foam for injectable oxygen delivery. 2010 Langmuir pmid:20873807
Yasuda A et al. Self-organizing map analysis using multivariate data from theophylline powders predicted by a thin-plate spline interpolation. 2010 J Pharm Sci pmid:20845452
Shaikh SA et al. Formulation and evaluation of s-(-)-amlodipine besylate and nebivolol hydrochloride tablets. 2010 J Adv Pharm Technol Res pmid:22247846
Dasu K et al. Hydrolysis of fluorotelomer compounds leading to fluorotelomer alcohol production during solvent extractions of soils. 2010 Chemosphere pmid:20801485
Tiwari G et al. Cyclodextrins in delivery systems: Applications. 2010 J Pharm Bioallied Sci pmid:21814436
Moore F et al. Improving the hardness of dry granulated tablets containing sodium lauryl sulfate. 2010 Int J Pharm pmid:20801204
Chen X et al. Plasma metabolomics reveals biomarkers of the atherosclerosis. 2010 J Sep Sci pmid:20730840
Shidhaye SS et al. Buccal drug delivery of pravastatin sodium. 2010 AAPS PharmSciTech pmid:20300898
Horne I et al. Two conserved Z9-octadecanoic acid desaturases in the red flour beetle, Tribolium castaneum. 2010 Gene pmid:20709164
Ion G et al. Maternal consumption of canola oil suppressed mammary gland tumorigenesis in C3(1) TAg mice offspring. 2010 BMC Cancer pmid:20205934
Vlachou M et al. Utilization of hydrophilic swellable polymers as carriers for sustained drug delivery from matrices and three layer tablet systems. 2010 Curr Drug Deliv pmid:20695845
Mas S et al. Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes. 2010 Diabetes pmid:20200316
Walker S et al. Synthesis, processing and solid state excipient interactions of cucurbit[6]uril and its formulation into tablets for oral drug delivery. 2010 Mol. Pharm. pmid:20669974
Kurian GA et al. Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. 2010 Chin Med pmid:20180993
Saravanakumari P and Mani K Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. 2010 Bioresour. Technol. pmid:20637606
Mathew M et al. Elevated plasma free fatty acids increase cardiovascular risk by inducing plasma biomarkers of endothelial activation, myeloperoxidase and PAI-1 in healthy subjects. 2010 Cardiovasc Diabetol pmid:20158910
van den Berg SA et al. High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity. 2010 Nutr Metab (Lond) pmid:20346174
Xing Z et al. The fabrication of novel nanobubble ultrasound contrast agent for potential tumor imaging. 2010 Nanotechnology pmid:20220227
Li Y et al. Preparation and characterization of coverage-controlled CaCO3 nanoparticles. 2010 J Colloid Interface Sci pmid:20202642
Romanowicz L and Bańkowski E Sphingolipids of human umbilical cord vein and their alteration in preeclampsia. 2010 Mol. Cell. Biochem. pmid:20155487
Abdel-Mottaleb MM et al. In vitro drug release mechanism from lipid nanocapsules (LNC). 2010 Int J Pharm pmid:20149853
Taneri F et al. In vitro and in vivo evaluation of oral tablet formulations prepared with ketoconazole and hydroxypropyl-beta-cyclodextrin. 2010 Drug Deliv pmid:20148713
Wang J et al. Lubrication in tablet formulations. 2010 Eur J Pharm Biopharm pmid:20096779
Dong J et al. Cation-controlled crystal growth of silver stearate: cryo-TEM investigation of lithium vs sodium stearate. 2010 Langmuir pmid:20017506
Fu X et al. A rapid and universal bacteria-counting approach using CdSe/ZnS/SiO2 composite nanoparticles as fluorescence probe. 2010 Anal Bioanal Chem pmid:20016878
Kushner J and Moore F Scale-up model describing the impact of lubrication on tablet tensile strength. 2010 Int J Pharm pmid:20667504
Zhang LJ et al. Hot-injection synthesis of highly luminescent and monodisperse CdS nanocrystals using thioacetamide and cadmium source with proper reactivity. 2010 J Colloid Interface Sci pmid:19932894
Imae R et al. Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. 2010 Mol. Biol. Cell pmid:20668164
Su C et al. A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC. 2010 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:20732836
Yoo HJ and HÃ¥kansson K Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. 2010 Anal. Chem. pmid:20704384
Balani PN et al. Influence of excipients in comilling on mitigating milling-induced amorphization or structural disorder of crystalline pharmaceutical actives. 2010 J Pharm Sci pmid:19902526
Yuan Y et al. A signal-on electrochemical probe-label-free aptasensor using gold-platinum alloy and stearic acid as enhancers. 2010 Biosens Bioelectron pmid:20708400
Yeop Han C et al. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. 2010 Diabetes pmid:19934003
Jian WX et al. [Detection and analysis on plasma metabolomics in patient with coronary heart disease of Xin-blood stasis syndrome pattern]. 2010 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:20815270
Gonzalez-Mira E et al. Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. 2010 Colloids Surf B Biointerfaces pmid:20719479
Raeside JI and Christie HL Diaryl dimers of estradiol and of estrone may be formed as major metabolites by mouse mammary glands. 2010 Biochem. Biophys. Res. Commun. pmid:20875396
Valencia-Chamorro SA et al. Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. 2010 J. Food Sci. pmid:21535515
Alloatti A et al. Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target. 2010 PLoS ONE pmid:21151902