| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Boutonneuse Fever | D001907 | 5 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchitis | D001991 | 6 associated lipids |
| Burns | D002056 | 34 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Föger F et al. | In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein. | 2006 | Biomaterials | pmid:16919723 |
| Zhao L et al. | Non-destructive determination of metronidazole powder by using artificial neural networks on short-wavelength NIR spectroscopy. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16920000 |
| Li W et al. | Mass-balanced blend uniformity analysis of pharmaceutical powders by at-line near-infrared spectroscopy with a fiber-optic probe. | 2006 | Int J Pharm | pmid:16920283 |
| Tsakalof AK et al. | Pitfalls in drying oils identification in art objects by gas chromatography. | 2006 | J Sep Sci | pmid:16922282 |
| Lee SH et al. | Fatty acid synthesis by elongases in trypanosomes. | 2006 | Cell | pmid:16923389 |
| Thompson W and MacDonald G | Isolation and characterization of cytidine diphosphate diglyceride from beef liver. | 1975 | J. Biol. Chem. | pmid:169258 |
| Harper DP and Wolcott MP | Chemical imaging of wood-polypropylene composites. | 2006 | Appl Spectrosc | pmid:16925926 |
| Morrisett JD et al. | Multiple thermotropic phase transitions in Escherichia coli membranes and membrane lipids. A comparison of results obtained by nitroxyl stearate paramagnetic resonance, pyrene excimer fluorescence, and enzyme activity measurements. | 1975 | J. Biol. Chem. | pmid:169264 |
| Govindarajan R et al. | Ionization states in the microenvironment of solid dosage forms: effect of formulation variables and processing. | 2006 | Pharm. Res. | pmid:16933092 |
| Murphy DJ | The extracellular pollen coat in members of the Brassicaceae: composition, biosynthesis, and functions in pollination. | 2006 | Protoplasma | pmid:16937052 |
| Miranda LA et al. | Performance of UASB and DAEB reactors in the anaerobic digestion of synthetic wastewater containing sodium oleate and sodium stereate. | 2006 | Water Sci. Technol. | pmid:16939093 |
| Colla E et al. | Amaranthus cruentus flour edible films: influence of stearic acid addition, plasticizer concentration, and emulsion stirring speed on water vapor permeability and mechanical properties. | 2006 | J. Agric. Food Chem. | pmid:16939322 |
| Asker AF et al. | Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions. | 1975 | Pharmazie | pmid:169527 |
| Tavilani H et al. | Decreased polyunsaturated and increased saturated fatty acid concentration in spermatozoa from asthenozoospermic males as compared with normozoospermic males. | 2006 | Andrologia | pmid:16961570 |
| Yao HT et al. | The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes. | 2006 | Life Sci. | pmid:16978661 |
| Ray K et al. | Distance-dependent metal-enhanced fluorescence from Langmuir-Blodgett monolayers of alkyl-NBD derivatives on silver island films. | 2006 | Langmuir | pmid:16981751 |
| Amakura Y et al. | Characteristic long-chain fatty acid of Pleurocybella porrigens. | 2006 | Shokuhin Eiseigaku Zasshi | pmid:16984039 |
| Kazmierczak SC et al. | Electron spin resonance spectroscopy of serum albumin: a novel new test for cancer diagnosis and monitoring. | 2006 | Clin. Chem. | pmid:16990414 |
| Singh H et al. | Metabolism of branched chain fatty acids in peroxisomal disorders. | 1990 | J. Inherit. Metab. Dis. | pmid:1700192 |
| Devillard E et al. | Rumen ciliate protozoa contain high concentrations of conjugated linoleic acids and vaccenic acid, yet do not hydrogenate linoleic acid or desaturate stearic acid. | 2006 | Br. J. Nutr. | pmid:17010229 |
| Carr TP and Jesch ED | Food components that reduce cholesterol absorption. | 2006 | Adv. Food Nutr. Res. | pmid:17011476 |
| Kurai J et al. | Acute eosinophilic pneumonia caused by calcium stearate, an additive agent for an oral antihistaminic medication. | 2006 | Intern. Med. | pmid:17016002 |
| Teixeira AC et al. | Phase behaviour of stearic acid-stearonitrile mixtures. A thermodynamic study in bulk and at the air-water interface. | 2006 Nov-Dec | Chem. Phys. Lipids | pmid:17027948 |
| Kamlekar RK and Swamy MJ | Studies on the critical micellar concentration and phase transitions of stearoylcarnitine. | 2006 | Biosci. Rep. | pmid:17029002 |
| Wu F and Gaffney BJ | Dynamic behavior of fatty acid spin labels within a binding site of soybean lipoxygenase-1. | 2006 | Biochemistry | pmid:17029406 |
| Johnston WL et al. | The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo. | 2006 | BMC Biol. | pmid:17042944 |
| Rasmussen HE et al. | Reduction in cholesterol absorption is enhanced by stearate-enriched plant sterol esters in hamsters. | 2006 | J. Nutr. | pmid:17056791 |
| Staiger K et al. | Saturated, but not unsaturated, fatty acids induce apoptosis of human coronary artery endothelial cells via nuclear factor-kappaB activation. | 2006 | Diabetes | pmid:17065351 |
| Ruan HL et al. | Ferulic acid esters from Euphorbia hylonoma. | 2007 | Fitoterapia | pmid:17067756 |
| Maia MR et al. | Metabolism of polyunsaturated fatty acids and their toxicity to the microflora of the rumen. | 2007 | Antonie Van Leeuwenhoek | pmid:17072533 |
| Kumon M et al. | Novel approach to DPI carrier lactose with mechanofusion process with additives and evaluation by IGC. | 2006 | Chem. Pharm. Bull. | pmid:17077547 |
| Sunagane N et al. | [Possibility of interactions between prescription drugs and OTC drugs (2nd report)--interaction between levodopa preparation and OTC Kampo medicines for upset stomach]. | 2006 | Yakugaku Zasshi | pmid:17077621 |
| Huang YF et al. | One new anthraquinone from marine Streptomyces sp. FX-58. | 2006 | Nat. Prod. Res. | pmid:17127510 |
| Sampath H et al. | Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. | 2007 | J. Biol. Chem. | pmid:17127673 |
| Huber AH et al. | Fatty acid-specific fluorescent probes and their use in resolving mixtures of unbound free fatty acids in equilibrium with albumin. | 2006 | Biochemistry | pmid:17128966 |
| Hirai N et al. | Improvement of the agitation granulation method to prepare granules containing a high content of a very hygroscopic drug. | 2006 | J. Pharm. Pharmacol. | pmid:17132205 |
| Forest PO et al. | Influence of gradual introduction of hydrophobic groups (stearic acid) in denatured atelocollagen on fibroblasts behavior in vitro. | 2007 | J Biomed Mater Res A | pmid:17133448 |
| Pleite R et al. | Increase of the stearic acid content in high-oleic sunflower (Helianthus annuus) seeds. | 2006 | J. Agric. Food Chem. | pmid:17147422 |
| John Wallace R et al. | Clostridium proteoclasticum: A ruminal bacterium that forms stearic acid from linoleic acid. | 2006 | FEMS Microbiol. Lett. | pmid:17147764 |
| Müller H et al. | Control of CaCO3 crystallization by demixing of monolayers. | 2006 | Langmuir | pmid:17154582 |
| Wong HL et al. | In vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model. | 2007 | Eur J Pharm Biopharm | pmid:17156986 |
| Klibanov AL et al. | Targeted ultrasound contrast agent for molecular imaging of inflammation in high-shear flow. | Contrast Media Mol Imaging | pmid:17191766 | |
| Salles HC et al. | The venomous secrets of the web droplets from the viscid spiral of the orb-weaver spider Nephila clavipes (Araneae, Tetragnatidae). | 2006 | Chem. Biodivers. | pmid:17193305 |
| Nichols KK et al. | Identification of fatty acids and fatty acid amides in human meibomian gland secretions. | 2007 | Invest. Ophthalmol. Vis. Sci. | pmid:17197513 |
| Mayer KM and Shanklin J | Identification of amino acid residues involved in substrate specificity of plant acyl-ACP thioesterases using a bioinformatics-guided approach. | 2007 | BMC Plant Biol. | pmid:17201914 |
| Cheng Y et al. | Studies on the structure and miscibility of mixed Langmuir-Blodgett films of a double-armed dibenzo-18-crown-6 ether with stearic acid. | 2007 | J Colloid Interface Sci | pmid:17207808 |
| Sae-be P et al. | Analysis of the products from enzymatic scouring of cotton. | 2007 | Biotechnol J | pmid:17219458 |
| Ando M et al. | Development and evaluation of a novel dry-coated tablet technology for pellets as a substitute for the conventional encapsulation technology. | 2007 | Int J Pharm | pmid:17223295 |
| Chalé-Rush A et al. | Multiple routes of chemosensitivity to free fatty acids in humans. | 2007 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:17234892 |
| Maduko CO et al. | Enzymatic interesterification of tripalmitin with vegetable oil blends for formulation of caprine milk infant formula analogs. | 2007 | J. Dairy Sci. | pmid:17235135 |
| Graves EL et al. | Factors affecting the concentration of sphingomyelin in bovine milk. | 2007 | J. Dairy Sci. | pmid:17235147 |
| Mosley SA et al. | Effect of varying levels of fatty acids from palm oil on feed intake and milk production in Holstein cows. | 2007 | J. Dairy Sci. | pmid:17235176 |
| Mehrotra A et al. | Influence of shear intensity and total shear on properties of blends and tablets of lactose and cellulose lubricated with magnesium stearate. | 2007 | Int J Pharm | pmid:17236729 |
| Otsuka M et al. | Chemoinformetrical evaluation of dissolution property of indomethacin tablets by near-infrared spectroscopy. | 2007 | J Pharm Sci | pmid:17238202 |
| Malmberg P et al. | Localization of lipids in the aortic wall with imaging TOF-SIMS. | 2007 | Biochim. Biophys. Acta | pmid:17240191 |
| Feldkamp T et al. | Alleviation of fatty acid and hypoxia-reoxygenation-induced proximal tubule deenergization by ADP/ATP carrier inhibition and glutamate. | 2007 | Am. J. Physiol. Renal Physiol. | pmid:17244890 |
| Cavallari C et al. | Enhanced release of indomethacin from Pvp/stearic acid microcapsules prepared coupling Co-freeze-drying and ultrasound assisted spray-congealing process. | 2007 | Pharm. Res. | pmid:17252191 |
| Zhu S et al. | Interaction of the acid soap of triethanolamine stearate and stearic acid with water. | 2007 | J Phys Chem B | pmid:17266256 |
| Abdel-Hameid NA | Protective role of dimethyl diphenyl bicarboxylate (DDB) against erythromycin induced hepatotoxicity in male rats. | 2007 | Toxicol In Vitro | pmid:17267170 |
| Jaimini M et al. | Formulation and evaluation of famotidine floating tablets. | 2007 | Curr Drug Deliv | pmid:17269917 |
| Simi CK and Emilia Abraham T | Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery. | 2007 | Bioprocess Biosyst Eng | pmid:17278045 |
| Ramirez-Dorronsoro JC et al. | Chargeability measurements of selected pharmaceutical dry powders to assess their electrostatic charge control capabilities. | 2006 | AAPS PharmSciTech | pmid:17285749 |
| Faqih AM et al. | Effect of moisture and magnesium stearate concentration on flow properties of cohesive granular materials. | 2007 | Int J Pharm | pmid:17289312 |
| Eltahlawy H et al. | Evidence for two-step regulation of pheromone biosynthesis by the pheromone biosynthesis-activating neuropeptide in the moth Heliothis virescens. | 2007 | Arch. Insect Biochem. Physiol. | pmid:17294424 |
| Tuomasjukka S et al. | Stearic acid is well absorbed from short- and long-acyl-chain triacylglycerol in an acute test meal. | 2007 | Eur J Clin Nutr | pmid:17299476 |
| Celleno L et al. | A Dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women. | 2007 | Int J Med Sci | pmid:17299581 |
| Weyenberg W et al. | Cytotoxicity of submicron emulsions and solid lipid nanoparticles for dermal application. | 2007 | Int J Pharm | pmid:17300887 |
| Wang ZJ et al. | Stearic acid protects primary cultured cortical neurons against oxidative stress. | 2007 | Acta Pharmacol. Sin. | pmid:17302992 |
| Kanthimathi M and Dhathathreyan A | Langmuir and Langmuir-Blodgett films of N-(4-octadecyloxy-2-hydroxybenzylidene) derivatives of amino acids. | 2007 | J Colloid Interface Sci | pmid:17306822 |
| Davies PN et al. | The determination of the mechanical strength of tablets of different shapes. | 2007 | Eur J Pharm Biopharm | pmid:17329086 |
| Cobb TK | Effects of dietary stearic acid on plasma cholesterol levels. | 1992 | South. Med. J. | pmid:1734530 |
| Deb S et al. | Langmuir-Blodgett films of p-terphenyl in different matrices: evidence of dual excimer. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17350881 |
| Mutch DM et al. | Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice. | 2007 | Genome Biol. | pmid:17355638 |
| Mutalik S et al. | Preparation, in vitro, preclinical and clinical evaluations of once daily sustained release tablets of aceclofenac. | 2007 | Arch. Pharm. Res. | pmid:17366745 |
| Grice DE et al. | Transcriptional profiling of C57 and DBA strains of mice in the absence and presence of morphine. | 2007 | BMC Genomics | pmid:17367521 |
| Vighi E et al. | Re-dispersible cationic solid lipid nanoparticles (SLNs) freeze-dried without cryoprotectors: characterization and ability to bind the pEGFP-plasmid. | 2007 | Eur J Pharm Biopharm | pmid:17368876 |
| Subauste AR and Burant CF | Role of FoxO1 in FFA-induced oxidative stress in adipocytes. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17374693 |
| de la Luz Reus Medina M and Kumar V | Comparative evaluation of powder and tableting properties of low and high degree of polymerization cellulose I and cellulose II excipients. | 2007 | Int J Pharm | pmid:17376616 |
| Ramstedt M et al. | Wet chemical silver treatment of endotracheal tubes to produce antibacterial surfaces. | 2007 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:17385236 |
| Rosenberger TA et al. | Bovine brain diacylglycerol lipase: substrate specificity and activation by cyclic AMP-dependent protein kinase. | 2007 | Lipids | pmid:17393225 |
| Richter K et al. | Localization of fatty acids with selective chain length by imaging time-of-flight secondary ion mass spectrometry. | 2007 | Microsc. Res. Tech. | pmid:17393479 |
| Ishak RA et al. | Preparation, in vitro and in vivo evaluation of stomach-specific metronidazole-loaded alginate beads as local anti-Helicobacter pylori therapy. | 2007 | J Control Release | pmid:17412443 |
| Koennings S et al. | Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices. | 2007 | J Control Release | pmid:17412444 |
| Bandyopadhyay P and Neeta NS | Evidence for vesicle formation from 1:1 nonionic surfactant span 60 and fatty alcohol mixtures in aqueous ethanol: potential delivery vehicle composition. | 2007 | Colloids Surf B Biointerfaces | pmid:17412571 |
| Crunkhorn S et al. | Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. | 2007 | J. Biol. Chem. | pmid:17416903 |
| Kamilya T et al. | Interaction and incorporation of ovalbumin with stearic acid monolayer: Langmuir-Blodgett film formation and deposition. | 2007 | Colloids Surf B Biointerfaces | pmid:17418542 |
| Liu J et al. | Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: preparation and characterization. | 2007 | Int J Pharm | pmid:17428627 |
| Pagliassotti MJ et al. | Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity. | 2007 | Endocrinology | pmid:17431009 |
| Barman S and Vasudevan S | Mixed saturated-unsaturated alkyl-chain assemblies: solid solutions of zinc stearate and zinc oleate. | 2007 | J Phys Chem B | pmid:17441755 |
| Lee J | Nanoscopic friction behavior of pharmaceutical materials. | 2007 | Int J Pharm | pmid:17442509 |
| Yuan H et al. | Studies on oral absorption of stearic acid SLN by a novel fluorometric method. | 2007 | Colloids Surf B Biointerfaces | pmid:17446050 |
| Shao Q et al. | Investigation of an artificial intelligence technology--Model trees. Novel applications for an immediate release tablet formulation database. | 2007 | Eur J Pharm Sci | pmid:17452096 |
| He X et al. | Mechanistic study of the effect of roller compaction and lubricant on tablet mechanical strength. | 2007 | J Pharm Sci | pmid:17455360 |
| Shao Q et al. | Comparison of neurofuzzy logic and decision trees in discovering knowledge from experimental data of an immediate release tablet formulation. | 2007 | Eur J Pharm Sci | pmid:17459671 |
| Chung DJ et al. | Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. | 2007 | Yonsei Med. J. | pmid:17461529 |
| Malhi H et al. | Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicity. | 2007 | Gut | pmid:17470478 |
| Kiliç T et al. | Fatty acid composition of seeds of some species of Nepeta L. | 2007 | Nat. Prod. Res. | pmid:17487620 |
| Yu DG et al. | Tablets with material gradients fabricated by three-dimensional printing. | 2007 | J Pharm Sci | pmid:17497729 |
| Liang L and Fang Y | Photoluminescence of a mixed Langmuir-Blodgett film of C(60) and stearic acid at room temperature. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17499018 |
| Nolan LM et al. | Combined effects of iontophoretic and chemical enhancement on drug delivery. II. Transport across human and murine skin. | 2007 | Int J Pharm | pmid:17502130 |