stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Bacterial Infections D001424 21 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Brain Edema D001929 20 associated lipids
Breast Neoplasms D001943 24 associated lipids
Bronchitis D001991 6 associated lipids
Burns D002056 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Lee YH et al. Separation and determination of polyethylene glycol fatty acid esters in cosmetics by a reversed-phase HPLC/ELSD. 2008 Talanta pmid:18371826
Santos IC et al. Paired-ion electrospray ionization--triple quadrupole tandem mass spectrometry for quantification of anionic surfactants in waters. 2015 Talanta pmid:26078166
Han GR and Jang CH Detection of heavy-metal ions using liquid crystal droplet patterns modulated by interaction between negatively charged carboxylate and heavy-metal cations. 2014 Talanta pmid:25059128
Norwitz G and Gordon H Determination of lithium stearate in sebacate-based lubricants by atomic absorption. 1973 Talanta pmid:18961363
Norwitz G and Galan M Determination of barium and strontium peroxides (active oxygen) in igniters in small-arms tracer ammunition. 1976 Talanta pmid:18961958
Ciszewski A and Lukaszewski Z Electrochemical masking for removal of the titanium matrix effect in DPASV determination of thallium. 1988 Talanta pmid:18964494
Jaumot J et al. Blending process modeling and control by multivariate curve resolution. 2013 Talanta pmid:24209372
Polásek M and Jambor M Chemiluminescence determination of antibacterial drug trimethoprim by automated sequential injection technique with permanganate and hexametaphosphate as reagents. 2002 Talanta pmid:18968863
Cakir T et al. Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. 2007 Theor Biol Med Model pmid:18070347
Ruddle P et al. Effect of a novel mutation in a Δ9-stearoyl-ACP-desaturase on soybean seed oil composition. 2013 Theor. Appl. Genet. pmid:22961205
Pérez-Vich B et al. Molecular analysis of the high stearic acid content in sunflower mutant CAS-14. 2006 Theor. Appl. Genet. pmid:16362273
Spencer MM et al. Mapping the Fas locus controlling stearic acid content in soybean. 2003 Theor. Appl. Genet. pmid:12595989
Han Y et al. Natural variations in stearoyl-acp desaturase genes affect the conversion of stearic to oleic acid in maize kernel. 2017 Theor. Appl. Genet. pmid:27717956
Fatouros DG et al. Clinical studies with oral lipid based formulations of poorly soluble compounds. 2007 Ther Clin Risk Manag pmid:18472981
Rawat MK et al. Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. 2010 Ther Deliv pmid:22816120
Klein J et al. Fatty acid ethyl esters: a novel biologic marker for heavy in utero ethanol exposure: a case report. 1999 Ther Drug Monit pmid:10604826
Zhen Z and Xie J Development of manganese-based nanoparticles as contrast probes for magnetic resonance imaging. 2012 Theranostics pmid:22272218
Geslin JM et al. [Allergic respiratory disorders and vein sclerosis with lauromacrogol 400]. Therapie pmid:15789831
Marlin GE et al. Plasma and sputum erythromycin concentrations in chronic bronchitis. 1980 Thorax pmid:7434299
VROMAN L EFFECTS OF HYDROPHOBIC SURFACES UPON BLOOD COAGULATION. 1964 Thromb Diath Haemorrh pmid:14113384