stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Bacterial Infections D001424 21 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Brain Edema D001929 20 associated lipids
Breast Neoplasms D001943 24 associated lipids
Bronchitis D001991 6 associated lipids
Burns D002056 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Rosén C et al. Acute otitis media in older children and adults treated with phenoxymethyl penicillin or erythromycin stearate. Bacteriological and immunological aspects. 1983 Sep-Oct Acta Otolaryngol. pmid:6416018
Walstad RA and Hellum KB Penetration of erythromycin in respiratory tract infections. 1984 Acta Otolaryngol Suppl pmid:6333775
Rosén C et al. Acute otitis media in older children and adults treated with penicillin or erythromycin. 1984 Acta Otolaryngol Suppl pmid:6437133
Larsson K and Glantz PO Microbial adhesion to surfaces with different surface charges. 1981 Acta Odontol. Scand. pmid:6948486
MAKLEIT JK et al. THIN LAYER AND GAS CHROMATOGRAPHIC ANALYSIS OF SYPHILIS ANTIGENS. 1964-1965 Acta Microbiol Acad Sci Hung pmid:14314670
Lassus A et al. Erythromycin and lymecycline treatment in chlamydia-positive and Chlamydia-negative non-gonococcal urethritis--a partner-controlled study. 1979 Acta Derm. Venereol. pmid:87096
Lundberg B Thermal properties of systems containing cholesteryl esters and triglycerides. 1976 Acta Chem. Scand., B, Org. Chem. Biochem. pmid:1266525
Liu TY and Lin YL Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. 2010 Acta Biomater pmid:19819354
Nouri A et al. Effect of process control agent on the porous structure and mechanical properties of a biomedical Ti-Sn-Nb alloy produced by powder metallurgy. 2010 Acta Biomater pmid:19815096
Xing Z et al. Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. 2010 Acta Biomater pmid:20226284
Ivanova EP et al. Bactericidal activity of self-assembled palmitic and stearic fatty acid crystals on highly ordered pyrolytic graphite. 2017 Acta Biomater pmid:28688988
Marchut E et al. The inhibitory effect of various fatty acids on aerobic glycolysis in Ehrlich ascites tumour cells. 1986 Acta Biochim. Pol. pmid:2940781
Rambaut PC and Johnston RS Prolonged weightlessness and calcium loss in man. 1979 Acta Astronaut pmid:11883480
Yang W et al. Facile Synthesis of Gd-Cu-In-S/ZnS Bimodal Quantum Dots with Optimized Properties for Tumor Targeted Fluorescence/MR In Vivo Imaging. 2015 ACS Appl Mater Interfaces pmid:26257133
He M et al. Controllable stearic acid crystal induced high hydrophobicity on cellulose film surface. 2013 ACS Appl Mater Interfaces pmid:23289586
Jun HY et al. Long residence time of ultrasound microbubbles targeted to integrin in murine tumor model. 2010 Acad Radiol pmid:19815430
Casiraghi A et al. The influence of the polar head and the hydrophobic chain on the skin penetration enhancement effect of poly(ethylene glycol) derivatives. 2012 AAPS PharmSciTech pmid:22232021
Tatavarti AS et al. Assessment of NIR spectroscopy for nondestructive analysis of physical and chemical attributes of sulfamethazine bolus dosage forms. 2005 AAPS PharmSciTech pmid:16353969
Nokhodchi A et al. Cogrinding as a tool to produce sustained release behavior for theophylline particles containing magnesium stearate. 2009 AAPS PharmSciTech pmid:19862623
Seitavuopio P et al. Monitoring tablet surface roughness during the film coating process. 2006 AAPS PharmSciTech pmid:16796349