| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Adenoma | D000236 | 40 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Anemia, Dyserythropoietic, Congenital | D000742 | 2 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Cholestasis, Extrahepatic | D001651 | 7 associated lipids |
| Birth Weight | D001724 | 23 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Boutonneuse Fever | D001907 | 5 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Bronchitis | D001991 | 6 associated lipids |
| Burns | D002056 | 34 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yin L et al. | Benzyl butyl phthalate promotes adipogenesis in 3T3-L1 preadipocytes: A High Content Cellomics and metabolomic analysis. | 2016 | Toxicol In Vitro | pmid:26820058 |
| MURATA H | [BIOCHEMICAL STUDIES ON PHYSIOLOGICAL UTILIZABILITY OF L-ASCORBYL STEARINE ESTER]. | 1964 | Tokyo Jikeikai Ika Daigaku Zasshi | pmid:14288523 |
| Okabe H et al. | Effects of anti-convulsants on fatty acid metabolism in human serum. | 1986 | Tohoku J. Exp. Med. | pmid:3705068 |
| Roshanai F et al. | Prostaglandin precursors in platelet phosphoglycerides following acute myocardial infarction. | 1981 Oct 1-15 | Thromb. Res. | pmid:6277036 |
| Mutanen M and Aro A | Coagulation and fibrinolysis factors in healthy subjects consuming high stearic or trans fatty acid diets. | 1997 | Thromb. Haemost. | pmid:9031457 |
| Del Turco S et al. | Parallel decrease of tissue factor surface exposure and increase of tissue factor microparticle release by the n-3 fatty acid docosahexaenoate in endothelial cells. | 2007 | Thromb. Haemost. | pmid:17598015 |
| VROMAN L | EFFECTS OF HYDROPHOBIC SURFACES UPON BLOOD COAGULATION. | 1964 | Thromb Diath Haemorrh | pmid:14113384 |
| Marlin GE et al. | Plasma and sputum erythromycin concentrations in chronic bronchitis. | 1980 | Thorax | pmid:7434299 |
| Geslin JM et al. | [Allergic respiratory disorders and vein sclerosis with lauromacrogol 400]. | Therapie | pmid:15789831 | |
| Zhen Z and Xie J | Development of manganese-based nanoparticles as contrast probes for magnetic resonance imaging. | 2012 | Theranostics | pmid:22272218 |
| Klein J et al. | Fatty acid ethyl esters: a novel biologic marker for heavy in utero ethanol exposure: a case report. | 1999 | Ther Drug Monit | pmid:10604826 |
| Rawat MK et al. | Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. | 2010 | Ther Deliv | pmid:22816120 |
| Fatouros DG et al. | Clinical studies with oral lipid based formulations of poorly soluble compounds. | 2007 | Ther Clin Risk Manag | pmid:18472981 |
| Ruddle P et al. | Effect of a novel mutation in a Δ9-stearoyl-ACP-desaturase on soybean seed oil composition. | 2013 | Theor. Appl. Genet. | pmid:22961205 |
| Pérez-Vich B et al. | Molecular analysis of the high stearic acid content in sunflower mutant CAS-14. | 2006 | Theor. Appl. Genet. | pmid:16362273 |
| Spencer MM et al. | Mapping the Fas locus controlling stearic acid content in soybean. | 2003 | Theor. Appl. Genet. | pmid:12595989 |
| Han Y et al. | Natural variations in stearoyl-acp desaturase genes affect the conversion of stearic to oleic acid in maize kernel. | 2017 | Theor. Appl. Genet. | pmid:27717956 |
| Cakir T et al. | Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. | 2007 | Theor Biol Med Model | pmid:18070347 |
| Manzano E et al. | Study of the GC-MS determination of the palmitic-stearic acid ratio for the characterisation of drying oil in painting: La Encarnación by Alonso Cano as a case study. | 2011 | Talanta | pmid:21530791 |
| Lee YH et al. | Separation and determination of polyethylene glycol fatty acid esters in cosmetics by a reversed-phase HPLC/ELSD. | 2008 | Talanta | pmid:18371826 |
| Santos IC et al. | Paired-ion electrospray ionization--triple quadrupole tandem mass spectrometry for quantification of anionic surfactants in waters. | 2015 | Talanta | pmid:26078166 |
| Han GR and Jang CH | Detection of heavy-metal ions using liquid crystal droplet patterns modulated by interaction between negatively charged carboxylate and heavy-metal cations. | 2014 | Talanta | pmid:25059128 |
| Norwitz G and Gordon H | Determination of lithium stearate in sebacate-based lubricants by atomic absorption. | 1973 | Talanta | pmid:18961363 |
| Norwitz G and Galan M | Determination of barium and strontium peroxides (active oxygen) in igniters in small-arms tracer ammunition. | 1976 | Talanta | pmid:18961958 |
| Ciszewski A and Lukaszewski Z | Electrochemical masking for removal of the titanium matrix effect in DPASV determination of thallium. | 1988 | Talanta | pmid:18964494 |
| Maia M et al. | A novel, direct, reagent-free method for the detection of beeswax adulteration by single-reflection attenuated total reflectance mid-infrared spectroscopy. | 2013 | Talanta | pmid:23598195 |
| Jaumot J et al. | Blending process modeling and control by multivariate curve resolution. | 2013 | Talanta | pmid:24209372 |
| Polásek M and Jambor M | Chemiluminescence determination of antibacterial drug trimethoprim by automated sequential injection technique with permanganate and hexametaphosphate as reagents. | 2002 | Talanta | pmid:18968863 |
| Wei TC | Quantitative determination of chemical composition of gallstones by infrared absorption spectrophotometry. | 1982 | Taiwan Yi Xue Hui Za Zhi | pmid:6954245 |
| Mirabi P et al. | Does different BMI influence oocyte and embryo quality by inducing fatty acid in follicular fluid? | 2017 | Taiwan J Obstet Gynecol | pmid:28420500 |
| Young AC et al. | Structural studies on human muscle fatty acid binding protein at 1.4 A resolution: binding interactions with three C18 fatty acids. | 1994 | Structure | pmid:7922029 |
| EBERHAGEN D et al. | [ON RADIATION-INDUCED CHANGE IN C18-LABELLED UNSATURATED FATTY ACIDS IN AQUEOUS AEREATED SOLUTION]. | 1965 | Strahlentherapie | pmid:14266124 |
| Kiuru PS and Wähälä K | Microwave-assisted synthesis of deuterium labeled estrogen fatty acid esters. | 2006 | Steroids | pmid:16198386 |
| Huntemann M et al. | Complete genome sequence of the thermophilic sulfur-reducer Hippea maritima type strain (MH(2)). | 2011 | Stand Genomic Sci | pmid:21886857 |
| Kiss H et al. | Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). | 2010 | Stand Genomic Sci | pmid:21304711 |
| Sun H et al. | Complete genome sequence of Desulfarculus baarsii type strain (2st14). | 2010 | Stand Genomic Sci | pmid:21304732 |
| Göker M et al. | Complete genome sequence of the thermophilic sulfur-reducer Desulfurobacterium thermolithotrophum type strain (BSA(T)) from a deep-sea hydrothermal vent. | 2011 | Stand Genomic Sci | pmid:22675590 |
| SALAZAR H | DIETHYLENE GLYCOL DISTEARATE EMBEDDING AND ULTRAMICROTOME SECTIONING FOR LIGHT MICROSCOPY. | 1964 | Stain Technol | pmid:14106797 |
| Liang L and Fang Y | Photoluminescence of a mixed Langmuir-Blodgett film of C(60) and stearic acid at room temperature. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17499018 |
| Deb S et al. | Langmuir-Blodgett films of p-terphenyl in different matrices: evidence of dual excimer. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17350881 |
| McHedlov-Petrossyan NO et al. | Fluorescent dye N,N'-dioctadecylrhodamine as a new interfacial acid-base indicator. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17681854 |
| de Sousa FF et al. | Low-temperature phase transformation studies in the stearic acid: C form. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25909902 |
| Zhao L et al. | Non-destructive determination of metronidazole powder by using artificial neural networks on short-wavelength NIR spectroscopy. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16920000 |
| Ishioka T et al. | Infrared and XAFS study on structure and transition behavior of zinc stearate. | 2000 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:10952134 |
| Ishioka T et al. | Infrared study on annealing effect on conformation of zinc stearate. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16875870 |
| Biswas S et al. | Formation of complex films with water-soluble CTAB molecules. | 2006 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16549387 |
| Lu L et al. | Near infrared spectroscopy of stearic acid adsorbed on montmorillonite. | 2010 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:20071218 |
| Xu G and Fang Y | Studies of surface-enhanced Raman scattering of C60 Langmuir-Blodgett film on a new substrate. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17889595 |
| Xu B and Yan B | Photophysical properties of novel lanthanide (Tb3+, Dy3+, Eu3+) complexes with long chain para-carboxyphenol ester p-L-benzoate (L=dodecanoyloxy, myristoyloxy, palmitoyloxy and stearoyloxy). | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16815090 |
| Chakradhar RP and Dinesh Kumar V | Water-repellent coatings prepared by modification of ZnO nanoparticles. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:22575349 |
| Desudchit P et al. | Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men. | 1984 | Southeast Asian J. Trop. Med. Public Health | pmid:6441265 |
| Stults BM et al. | Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease. | 1983 | South. Med. J. | pmid:6857302 |
| Cobb TK | Effects of dietary stearic acid on plasma cholesterol levels. | 1992 | South. Med. J. | pmid:1734530 |
| Molloy PL and Eisenstadt JM | Erythromycin resistance in mouse L cells. | 1979 | Somatic Cell Genet. | pmid:531731 |
| Dave PC et al. | Calculating order parameter profiles utilizing magnetically aligned phospholipid bilayers for 2H solid-state NMR studies. | 2003 Sep-Nov | Solid State Nucl Magn Reson | pmid:12943910 |
| Coulomb B et al. | Biafine applied on human epidermal wounds is chemotactic for macrophages and increases the IL-1/IL-6 ratio. | 1997 | Skin Pharmacol. | pmid:9449167 |
| Amakura Y et al. | Characteristic long-chain fatty acid of Pleurocybella porrigens. | 2006 | Shokuhin Eiseigaku Zasshi | pmid:16984039 |
| Dou M et al. | [Orthogonal experiments for optimizing the formulation and preparation conditions of temozolomide solid lipid nanoparticles]. | 2008 | Sheng Wu Yi Xue Gong Cheng Xue Za Zhi | pmid:19024463 |
| Robson HG et al. | Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis. | 1983 Jul-Sep | Sex Transm Dis | pmid:6648747 |
| Hashisaki P et al. | Erythromycin failure in the treatment of syphilis in a pregnant woman. | 1983 Jan-Mar | Sex Transm Dis | pmid:6601848 |
| Oriel JD et al. | Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. | 1982 Oct-Dec | Sex Transm Dis | pmid:6821502 |
| Broderick PA and Kolodny EH | Biosensors for brain trauma and dual laser doppler flowmetry: enoxaparin simultaneously reduces stroke-induced dopamine and blood flow while enhancing serotonin and blood flow in motor neurons of brain, in vivo. | 2011 | Sensors (Basel) | pmid:22346571 |
| Zhang Y and Clapp A | Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. | 2011 | Sensors (Basel) | pmid:22247651 |
| Milanovic J et al. | Microencapsulation of flavors in carnauba wax. | 2010 | Sensors (Basel) | pmid:22315575 |
| GarcÃa MS et al. | Development of membrane selective electrode for determination of the antipsychotic sulpiride in pharmaceuticals and urine. | 2009 | Sensors (Basel) | pmid:22408528 |
| Wang L et al. | [Synthesis, characterization and evaluation of octadecyl ester-bonded monolithic column]. | 2005 | Se Pu | pmid:16350795 |
| Zhang Q et al. | [Retention behavior of solutes on liquid chromatographic column packed with dynamically modified zirconia]. | 1999 | Se Pu | pmid:12549113 |
| Oriel JD et al. | Comparison of erythromycin stearate and oxytetracycline in the treatment of non-gonococcal urethritis: their efficacy against Chlamydia trachomatis. | 1977 | Scott Med J | pmid:601555 |
| Leese GP et al. | Effects of growth hormone treatment on red cell plasma membrane fatty acid constituents in hypopituitary adults. | 2000 | Scott Med J | pmid:11130294 |
| Yavuz B et al. | An overview on dry eye treatment: approaches for cyclosporin a delivery. | 2012 | ScientificWorldJournal | pmid:22619624 |
| Liau CP et al. | Preparation and characterization of polyhydroxybutyrate/polycaprolactone nanocomposites. | 2014 | ScientificWorldJournal | pmid:24600329 |
| Woo JO et al. | Development of a controlled release of salicylic acid loaded stearic acid-oleic acid nanoparticles in cream for topical delivery. | 2014 | ScientificWorldJournal | pmid:24578624 |
| Pan S et al. | Particle formation by supercritical fluid extraction and expansion process. | 2013 | ScientificWorldJournal | pmid:24223031 |
| Shah KU and Khan GM | Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. | 2012 | ScientificWorldJournal | pmid:22649325 |
| Agostini F et al. | Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. | 2012 | ScientificWorldJournal | pmid:22593706 |
| Viswanathan R et al. | Strained-layer van der Waals epitaxy in a Langmuir-Blodgett film. | 1993 | Science | pmid:8392751 |
| Pouget EM et al. | The initial stages of template-controlled CaCO3 formation revealed by cryo-TEM. | 2009 | Science | pmid:19286549 |
| KORN ED and GREENBLATT CL | SYNTHESIS OF ALPHA-LINOLENIC ACID BY LEISHMANIA ENRIETTII. | 1963 | Science | pmid:14074842 |
| GERSHFELD NL and SHANES AM | Antagonism of veratrine by calcium ion in monolayers of stearic acid. | 1959 | Science | pmid:13658972 |
| Roberts L | Beef and chocolate: a partial reprieve. | 1988 | Science | pmid:3375809 |
| ROSENBERG MD | Cell guidance by alterations in monomolecular films. | 1963 | Science | pmid:13974905 |
| Takamoto DY et al. | Stable ordering in Langmuir-Blodgett films. | 2001 | Science | pmid:11509723 |
| Tse AG et al. | A glycophospholipid tail at the carboxyl terminus of the Thy-1 glycoprotein of neurons and thymocytes. | 1985 | Science | pmid:2865810 |
| Liu Z et al. | A novel stearic acid-modified hirudin peptidomimetic with improved pharmacokinetic properties and anticoagulant activity. | 2015 | Sci Rep | pmid:26400022 |
| Miao H et al. | Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1α pathway in chondrocytes. | 2015 | Sci Rep | pmid:26271607 |
| Fala AM et al. | Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α. | 2015 | Sci Rep | pmid:26237540 |
| Li C et al. | Enhanced performance and interfacial investigation of mineral-based composite phase change materials for thermal energy storage. | 2013 | Sci Rep | pmid:23712069 |
| Astanina K et al. | Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells. | 2015 | Sci Rep | pmid:26095213 |
| Wu MH et al. | A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. | 2014 | Sci Rep | pmid:24651079 |
| Lee W et al. | Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis. | 2017 | Sci Rep | pmid:28250431 |
| Khan FN and Dehghan MH | Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. | 2012 Jan-Mar | Sci Pharm | pmid:22396916 |
| Pujeri SS et al. | Stress degradation studies on varenicline tartrate and development of a validated stability-indicating HPLC method. | 2012 Jan-Mar | Sci Pharm | pmid:22396908 |
| Tomuta I et al. | High-Throughput NIR-Chemometric Method for Meloxicam Assay from Powder Blends for Tableting. | 2011 Oct-Dec | Sci Pharm | pmid:22145112 |
| Malik K et al. | Taste masked microspheres of ofloxacin: formulation and evaluation of orodispersible tablets. | 2011 Jul-Sep | Sci Pharm | pmid:21886910 |
| Zaid AN et al. | Formulation and bioequivalence of two valsartan tablets after a single oral administration. | 2011 Jan-Mar | Sci Pharm | pmid:21617777 |
| Shah DA et al. | Stability indicating LC-method for estimation of paracetamol and lornoxicam in combined dosage form. | 2011 Jan-Mar | Sci Pharm | pmid:21617776 |
| Aburahma MH et al. | Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid. | 2010 Apr-Jun | Sci Pharm | pmid:21179352 |
| Singh B et al. | Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride. | 2010 Apr-Jun | Sci Pharm | pmid:21179349 |
| Chaturvedi K et al. | Floating matrix dosage form for propranolol hydrochloride based on gas formation technique: development and in vitro evaluation. | 2010 Oct-Dec | Sci Pharm | pmid:21179326 |
| Nanjwade BK et al. | Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. | 2011 Oct-Dec | Sci Pharm | pmid:22145101 |