stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Bacterial Infections D001424 21 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Brain Edema D001929 20 associated lipids
Breast Neoplasms D001943 24 associated lipids
Bronchitis D001991 6 associated lipids
Burns D002056 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Boiret M et al. Setting local rank constraints by orthogonal projections for image resolution analysis: application to the determination of a low dose pharmaceutical compound. 2015 Anal. Chim. Acta pmid:26388474
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de Paiva EJ et al. Influence of two different alcohols in the esterification of fatty acids over layered zinc stearate/palmitate. 2015 Bioresour. Technol. pmid:26143001
Ricci M et al. Growth and Dissolution of Calcite in the Presence of Adsorbed Stearic Acid. 2015 Langmuir pmid:26087312
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Bera H et al. Alginate gel-coated oil-entrapped alginate-tamarind gum-magnesium stearate buoyant beads of risperidone. 2015 Int. J. Biol. Macromol. pmid:25861741
Badal Tejedor M et al. Tablet mechanics depend on nano and micro scale adhesion, lubrication and structure. 2015 Int J Pharm pmid:25841569
Rozman Peterka T et al. Solid state compatibility study and characterization of a novel degradation product of tacrolimus in formulation. 2015 J Pharm Biomed Anal pmid:25804434
Kelidari HR et al. Formulation optimization and in vitro skin penetration of spironolactone loaded solid lipid nanoparticles. 2015 Colloids Surf B Biointerfaces pmid:25797482
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Su Y et al. Redox-responsive polymer-drug conjugates based on doxorubicin and chitosan oligosaccharide-g-stearic acid for cancer therapy. 2015 Mol. Pharm. pmid:25751168
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Foraita S et al. Impact of the oxygen defects and the hydrogen concentration on the surface of tetragonal and monoclinic ZrO2 on the reduction rates of stearic acid on Ni/ZrO2. 2015 Chemistry pmid:25504844
Yan S et al. Autoxidated linolenic acid inhibits aflatoxin biosynthesis in Aspergillus flavus via oxylipin species. 2015 Fungal Genet. Biol. pmid:25498164
Yang Y et al. Ligand-directed stearic acid grafted chitosan micelles to increase therapeutic efficacy in hepatic cancer. 2015 Mol. Pharm. pmid:25495890
Yi HX et al. Effect of anionic PEGylated polypeptide on gene transfection mediated by glycolipid conjugate micelles. 2015 Mol. Pharm. pmid:25490413
Leonardi A et al. Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit. 2015 Int J Pharm pmid:25448580
Bootello MA et al. Effect of solvents on the fractionation of high oleic-high stearic sunflower oil. 2015 Food Chem pmid:25442612
Thakral NK et al. Compression-induced crystallization of amorphous indomethacin in tablets: characterization of spatial heterogeneity by two-dimensional X-ray diffractometry. 2015 Mol. Pharm. pmid:25438193
Liu Z et al. Process optimization and kinetic evaluation for biosynthesis of D-isoascorbyl stearate. 2015 Bioprocess Biosyst Eng pmid:25407728
Askari M et al. Tissue fatty acid composition and secretory phospholipase-A2 activity in oral squamous cell carcinoma. 2015 Clin Transl Oncol pmid:25351172
Qu L et al. Investigation of the potential for direct compaction of a fine ibuprofen powder dry-coated with magnesium stearate. 2015 Drug Dev Ind Pharm pmid:24738790
Vervaeck A et al. Fatty acids for controlled release applications: A comparison between prilling and solid lipid extrusion as manufacturing techniques. 2015 Eur J Pharm Biopharm pmid:26428938
Momoh MA et al. Influence of magnesium stearate on the physicochemical and pharmacodynamic characteristics of insulin-loaded Eudragit entrapped mucoadhesive microspheres. 2015 Drug Deliv pmid:24670092
Mohanty B et al. Development and characterization of itraconazole-loaded solid lipid nanoparticles for ocular delivery. 2015 Pharm Dev Technol pmid:24490828
Guadalupe Sánchez-González E et al. The influence of polymorphism on the manufacturability and in vitro dissolution of sulindac-containing hard gelatin capsules. 2015 Pharm Dev Technol pmid:24417644
Van Hoeck V et al. Interaction between differential gene expression profile and phenotype in bovine blastocysts originating from oocytes exposed to elevated non-esterified fatty acid concentrations. 2015 Reprod. Fertil. Dev. pmid:24360349
Nandini PT et al. Formulation and evaluation of gemcitabine-loaded solid lipid nanoparticles. 2015 Drug Deliv pmid:24283392
Chen Q et al. Preparation and characterization of glycyrrhetinic acid-modified stearic acid-grafted chitosan micelles. 2015 Artif Cells Nanomed Biotechnol pmid:24093764
Doignon F et al. Requirement of Phosphoinositides Containing Stearic Acid To Control Cell Polarity. 2015 Mol. Cell. Biol. pmid:26711260
Miyazaki Y et al. Dry Powder Coating using Planetary Centrifugal Mixer. 2015 J Pharm Pharm Sci pmid:26517137
Imran M and Nadeem M Triacylglycerol composition, physico-chemical characteristics and oxidative stability of interesterified canola oil and fully hydrogenated cottonseed oil blends. 2015 Lipids Health Dis pmid:26510410
Conde-Sieira M et al. Hypothalamic fatty acid sensing in Senegalese sole (Solea senegalensis): response to long-chain saturated, monounsaturated, and polyunsaturated (n-3) fatty acids. 2015 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:26468264
Iwao Y [Efficient Pharmaceutical Formulation Designs and Their Development Using Mathematical and Statistical Analysis]. 2015 Yakugaku Zasshi pmid:26423868
Liu Z et al. A novel stearic acid-modified hirudin peptidomimetic with improved pharmacokinetic properties and anticoagulant activity. 2015 Sci Rep pmid:26400022
Miao H et al. Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1α pathway in chondrocytes. 2015 Sci Rep pmid:26271607
Soliman HM et al. Utilization of Stearic acid Extracted from Olive Pomace for Production of Triazoles, Thiadiazoles and Thiadiazines Derivatives of Potential Biological Activities. 2015 J Oleo Sci pmid:26250422
Fala AM et al. Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3α. 2015 Sci Rep pmid:26237540
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Gotoh K et al. Introduction of Atmospheric Pressure Plasma to Aqueous Detergent Processes. 2015 J Oleo Sci pmid:26179001
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Sasakura D et al. Application of the quantitative detection of a change in concentration of magnesium stearate in a feeder tube of tableting manufacture by real-time near-infrared spectroscopy. 2015 Pharmazie pmid:26601418