stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Adenoma D000236 40 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Alzheimer Disease D000544 76 associated lipids
Amnesia D000647 12 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Olfaction Disorders D000857 17 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Arteriosclerosis D001161 86 associated lipids
Bacterial Infections D001424 21 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Birth Weight D001724 23 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Brain Edema D001929 20 associated lipids
Breast Neoplasms D001943 24 associated lipids
Bronchitis D001991 6 associated lipids
Burns D002056 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Lee I and Kadenbach B Palmitate decreases proton pumping of liver-type cytochrome c oxidase. 2001 Eur. J. Biochem. pmid:11737187
Kuppuswamy R et al. Estimation of capping incidence by indentation fracture tests. 2001 AAPS PharmSci pmid:11741256
Otsuka M et al. Comparative evaluation of tableting compression behaviors by methods of internal and external lubricant addition: inhibition of enzymatic activity of trypsin preparation by using external lubricant addition during the tableting compression process. 2001 AAPS PharmSci pmid:11741271
Mackin L et al. The impact of low levels of amorphous material (<5%) on the blending characteristics of a direct compression formulation. 2002 Int J Pharm pmid:11755273
Comai K et al. Analyses of renal medullary lipid droplets from normal, hydronephrotic, and indomethacin treated rabbits. 1975 Lipids pmid:1177669
Jensen RG et al. Parenteral infusion of a lactating woman with intralipid: changes in milk and plasma fatty acids. 2001 Adv. Exp. Med. Biol. pmid:11787679
Yu MD et al. The effect of formulation on reduced radioiodide thyroid uptake. 2002 J. Nucl. Med. pmid:11801703
Pedrazzi V et al. Tensile bond strength of a polymeric intra-buccal bioadhesive: the mucin role. 2001 Nov-Dec Boll Chim Farm pmid:11822242
Papanikolaou S et al. Kinetic profile of the cellular lipid composition in an oleaginous Yarrowia lipolytica capable of producing a cocoa-butter substitute from industrial fats. 2001 Antonie Van Leeuwenhoek pmid:11827207
Bassilian S et al. Loss of regulation of lipogenesis in the Zucker diabetic rat. II. Changes in stearate and oleate synthesis. 2002 Am. J. Physiol. Endocrinol. Metab. pmid:11832351
Anderson RR et al. Composition of cottontail rabbit milk from stomachs of young and directly from gland. 1975 J. Dairy Sci. pmid:1184805
Shu T et al. Studies of rapidly disintegrating tablets in the oral cavity using co-ground mixtures of mannitol with crospovidone. 2002 Chem. Pharm. Bull. pmid:11848208
Gaginella TS et al. Actions of ricinoleic acid and structurally related fatty acids on the gastrointestinal tract. II. Effects on water and electrolyte absorption in vitro. 1975 J. Pharmacol. Exp. Ther. pmid:1185605
Kidokoro M et al. Application of fluidized hot-melt granulation (FHMG) for the preparation of granules for tableting; properties of granules and tablets prepared by FHMG. 2002 Drug Dev Ind Pharm pmid:11858526
Mosley EE et al. Microbial biohydrogenation of oleic acid to trans isomers in vitro. 2002 J. Lipid Res. pmid:11861671
Smith RW and Walsh A Composition of liver lipids of the rat during pregnancy and lactation. 1975 Lipids pmid:1186452
Lippacher A et al. Semisolid SLN dispersions for topical application: influence of formulation and production parameters on viscoelastic properties. 2002 Eur J Pharm Biopharm pmid:11879997
Rambaut PC and Johnston RS Prolonged weightlessness and calcium loss in man. 1979 Acta Astronaut pmid:11883480
Schmidt P et al. [Animal experiments on barium stearate toxicity]. 1975 Z Gesamte Hyg pmid:1189478
Pan J and Chung FL Formation of cyclic deoxyguanosine adducts from omega-3 and omega-6 polyunsaturated fatty acids under oxidative conditions. 2002 Chem. Res. Toxicol. pmid:11896684
Palma S et al. Design of Peumus boldus tablets by direct compression using a novel dry plant extract. 2002 Int J Pharm pmid:11897423
Muzíková J [Effect of magnesium stearate on the tensile strength of tablets made with the binder Prosolv SMCC 90]. 2002 Ceska Slov Farm pmid:11910741
Long GT et al. Hard to swallow dry: kinetics and mechanism of the anhydrous thermal decomposition of acetylsalicylic acid. 2002 J Pharm Sci pmid:11920766
Yokoyama K et al. Computerized posturography with sway frequency analysis: application in occupational and environmental health. 2002 Ind Health pmid:11926510
Gravena C et al. Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans. 2002 J. Endocrinol. pmid:11927386
Kushibiki S et al. Effect of beta-lactoglobulin on plasma retinol and triglyceride concentrations, and fatty acid composition in calves. 2001 J. Dairy Res. pmid:11928954
Wanten GJ et al. Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. 2002 Eur. J. Clin. Invest. pmid:11952815
Sato M et al. [Clinical studies on OE-7 chiefly in the treatment of acute respiratory infections (author's transl)]. 1975 Jpn J Antibiot pmid:1195513
Yao Y et al. Regulation of triacylglycerol and phospholipid trafficking by fatty acids in newborn swine enterocytes. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11960778
Møller JK et al. Effect of nitrosylmyoglobin and saturated fatty acid anions on metmyoglobin-catalyzed oxidation of aqueous methyl linoleate emulsions. 2002 Biochim. Biophys. Acta pmid:11985897
Eromosele CO and Eromosele IC Fatty acid compositions of seed oils of Haematostaphis barteri and Ximenia americana. 2002 Bioresour. Technol. pmid:11991081
Ali J et al. Buccoadhesive erodible disk for treatment of oro-dental infections: design and characterisation. 2002 Int J Pharm pmid:11996813
Bolwell GP et al. The apoplastic oxidative burst in response to biotic stress in plants: a three-component system. 2002 J. Exp. Bot. pmid:11997382
Alhamami OM The effects of some physico-chemical factors and pharmaceutical excipients on the bioavailability of nitrofurantoin oily and aqueous suspensions in rats. 2002 Drug Dev Ind Pharm pmid:12026223
Dobbins RL et al. The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats. 2002 Diabetes pmid:12031970
Kelly FD et al. Short-term diets enriched in stearic or palmitic acids do not alter plasma lipids, platelet aggregation or platelet activation status. 2002 Eur J Clin Nutr pmid:12032647
Hu PC and Chen BH Effects of riboflavin and fatty acid methyl esters on cholesterol oxidation during illumination. 2002 J. Agric. Food Chem. pmid:12033831
Cozzini P et al. Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 1. Models without explicit constrained water. 2002 J. Med. Chem. pmid:12036355
Ohta N and Hatta I Interaction among molecules in mixtures of ceramide/stearic acid, ceramide/cholesterol and ceramide/stearic acid/cholesterol. 2002 Chem. Phys. Lipids pmid:12047901
Singhal R et al. Immobilization of urease on poly(N-vinyl carbazole)/stearic acid Langmuir-Blodgett films for application to urea biosensor. 2002 Biosens Bioelectron pmid:12052355
Kashefi K et al. Geoglobus ahangari gen. nov., sp. nov., a novel hyperthermophilic archaeon capable of oxidizing organic acids and growing autotrophically on hydrogen with Fe(III) serving as the sole electron acceptor. 2002 Int. J. Syst. Evol. Microbiol. pmid:12054231
Aveldano MI and Bazán NG Rapid production of diacylglycerols enriched in arachidonate and stearate during early brain ischemia. 1975 J. Neurochem. pmid:1206411
Williams RO et al. Investigation of excipient type and level on drug release from controlled release tablets containing HPMC. 2002 Pharm Dev Technol pmid:12066573
Liu Q et al. High-oleic and high-stearic cottonseed oils: nutritionally improved cooking oils developed using gene silencing. 2002 J Am Coll Nutr pmid:12071306
Schmidt LE and Dalhoff K Food-drug interactions. 2002 Drugs pmid:12093316
Liang X et al. Mass spectrometric analysis of GAP-43/neuromodulin reveals the presence of a variety of fatty acylated species. 2002 J. Biol. Chem. pmid:12105219
Anwar F et al. Analytical characterization of Salicornia bigelovii seed oil cultivated in Pakistan. 2002 J. Agric. Food Chem. pmid:12105947
Sebti I et al. Edible bioactive fatty acid-cellulosic derivative composites used in food-packaging applications. 2002 J. Agric. Food Chem. pmid:12105960
Østdal H et al. Reaction between protein radicals and other biomolecules. 2002 Free Radic. Biol. Med. pmid:12106816
Cao X et al. Langmuir and Langmuir-Blodgett films of a novel tryptophan peptide lipid. 2002 Chem. Commun. (Camb.) pmid:12122989