stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Obesity, Abdominal D056128 3 associated lipids
Atherosclerosis D050197 85 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Weight Gain D015430 101 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Yaws D015001 4 associated lipids
Whooping Cough D014917 6 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Urticaria D014581 13 associated lipids
Urethritis D014526 9 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Tremor D014202 15 associated lipids
Thrombosis D013927 49 associated lipids
Tenosynovitis D013717 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Sasaki T and Tanaka S Adsorption behavior of some aromatic compounds on hydrophobic magnetite for magnetic separation. 2011 J. Hazard. Mater. pmid:21962863
Mottram AR et al. Fatty acids antagonize bupivacaine-induced I(Na) blockade. 2011 Clin Toxicol (Phila) pmid:21970771
Sheikh KA et al. Influence of hydration state and homologue composition of magnesium stearate on the physical chemical properties of liquid paraffin lipogels. 2011 Int J Pharm pmid:21457766
Severino P et al. Polymorphism, crystallinity and hydrophilic-lipophilic balance of stearic acid and stearic acid-capric/caprylic triglyceride matrices for production of stable nanoparticles. 2011 Colloids Surf B Biointerfaces pmid:21543196
Zhou QT et al. Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties. 2011 Int J Pharm pmid:21527321
Manzano E et al. Study of the GC-MS determination of the palmitic-stearic acid ratio for the characterisation of drying oil in painting: La Encarnación by Alonso Cano as a case study. 2011 Talanta pmid:21530791
Prabhakar N et al. Polyaniline Langmuir-Blodgett film based aptasensor for ochratoxin A detection. 2011 Biosens Bioelectron pmid:21514815
Fini A et al. Diclofenac salts, part 6: release from lipid microspheres. 2011 J Pharm Sci pmid:21523784
Dani KG et al. Structural and functional analyses of a saturated acyl ACP thioesterase, type B from immature seed tissue of Jatropha curcas. 2011 Plant Biol (Stuttg) pmid:21489096
Broderick PA and Kolodny EH Biosensors for brain trauma and dual laser doppler flowmetry: enoxaparin simultaneously reduces stroke-induced dopamine and blood flow while enhancing serotonin and blood flow in motor neurons of brain, in vivo. 2011 Sensors (Basel) pmid:22346571
Rojas J and Kumar V Comparative evaluation of silicified microcrystalline cellulose II as a direct compression vehicle. 2011 Int J Pharm pmid:21708237
Veit M and Thaa B Association of influenza virus proteins with membrane rafts. 2011 Adv Virol pmid:22312341
Guan Q et al. Preparation and pharmacokinetics of solid lipid nanoparticles loaded with pueraria flavones. 2011 J Control Release pmid:22195890
Pingali K et al. Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions. 2011 Drug Dev Ind Pharm pmid:20942612
Arora G et al. Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum. 2011 J Adv Pharm Technol Res pmid:22171313
Sathiyaraj S et al. Lornoxicam gastro retentive floating matrix tablets: Design and in vitro evaluation. 2011 J Adv Pharm Technol Res pmid:22171312
Solanki SS and Dahima R Formulation and evaluation of aceclofenac mouth-dissolving tablet. 2011 J Adv Pharm Technol Res pmid:22171305
Negi JS et al. Effect of bioadhesion on initial in vitro buoyancy of effervescent floating matrix tablets of ciprofloxacin HCL. 2011 J Adv Pharm Technol Res pmid:22171304
Stahl J et al. The effect of formulation vehicles on the in vitro percutaneous permeation of ibuprofen. 2011 BMC Pharmacol. pmid:22168832
Yin AW and Huang SJ [Research on chemical constituents of xuefu zhuyu decoction]. 2011 Zhong Yao Cai pmid:22372145
Rajpurohit H et al. Hordeum vulgare hull in the design of fast disintegrating tablets. 2011 J Young Pharm pmid:21897660
Patel D et al. Design of Controlled Release Non-erodible Polymeric Matrix Tablet Using Microwave Oven-assisted Sintering Technique. 2011 J Young Pharm pmid:21897655
Huntemann M et al. Complete genome sequence of the thermophilic sulfur-reducer Hippea maritima type strain (MH(2)). 2011 Stand Genomic Sci pmid:21886857
Hu C et al. Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum. 2011 Biotechnol Biofuels pmid:21864398
Véret J et al. Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells. 2011 Biochem. J. pmid:21592087
Eggerath J et al. EDX-Element Analysis of the In Vitro Effect of Fluoride Oral Hygiene Tablets on Artificial Caries Lesion Formation and Remineralization in Human Enamel. 2011 Open Dent J pmid:21687564
Jeon I et al. Evaluation of roll compaction as a preparation method for hydroxypropyl cellulose-based matrix tablets. 2011 J Pharm Bioallied Sci pmid:21687348
Tong M et al. The effect of Zn-Al-hydrotalcites composited with calcium stearate and β-diketone on the thermal stability of PVC. 2011 Int J Mol Sci pmid:21673921
Feng H et al. Pharmacokinetics study of bio-adhesive tablet of Panax notoginseng saponins. 2011 Int Arch Med pmid:21658246
Elokely KM et al. Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent. 2011 Int J Anal Chem pmid:21647288
Lim J et al. Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8. 2011 PLoS ONE pmid:21674045
Sahu SK et al. Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel. 2011 J Drug Target pmid:20367067
Salem H et al. Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler. 2011 Int J Nanomedicine pmid:21383856
Nicholls HT et al. Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. 2011 Diabetes pmid:21378177
Meng Y et al. Two-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase. 2011 Biotechnol Biofuels pmid:21366905
Idris AM Screening of conditions controlling spectrophotometric sequential injection analysis. 2011 Chem Cent J pmid:21333024
Ordelheide AM et al. The myocyte expression of adiponectin receptors and PPARδ is highly coordinated and reflects lipid metabolism of the human donors. 2011 Exp Diabetes Res pmid:21331343
Gallardo LA et al. Europium stearate additives delay oxidation of UHMWPE for orthopaedic applications: a pilot study. 2011 Clin. Orthop. Relat. Res. pmid:21153455
Gilani K et al. Development of respirable nanomicelle carriers for delivery of amphotericin B by jet nebulization. 2011 J Pharm Sci pmid:20602350
Liu D et al. Synthesis and characterization of upconverting NaYF4:Er3+, Yb3+ nanocrystals via thermal decomposition of stearate precursor. 2011 J Nanosci Nanotechnol pmid:22413291
Hayashi Y et al. Modeling of latent structure of indomethacin solid dispersion tablet using Bayesian networks. 2011 Drug Dev Ind Pharm pmid:21702729
Naumowicz M et al. Impedance analysis of complex formation equilibria in phosphatidylcholine bilayers containing decanoic acid or decylamine. 2011 Cell Biochem. Biophys. pmid:21340532
Hsouna AB et al. Chemical composition, cytotoxicity effect and antimicrobial activity of Ceratonia siliqua essential oil with preservative effects against Listeria inoculated in minced beef meat. 2011 Int. J. Food Microbiol. pmid:21601302
Gallardo LA et al. Effect of europium(II) stearate on the mechanical properties and the oxidation resistance of UHMWPE. 2011 J Mech Behav Biomed Mater pmid:21565729
Abdel-Mottaleb MM et al. Lipid nanocapsules for dermal application: a comparative study of lipid-based versus polymer-based nanocarriers. 2011 Eur J Pharm Biopharm pmid:21558002
Khan FN and Dehghan MH Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. 2011 AAPS PharmSciTech pmid:21879394
Tsai MJ et al. Oral apomorphine delivery from solid lipid nanoparticles with different monostearate emulsifiers: pharmacokinetic and behavioral evaluations. 2011 J Pharm Sci pmid:20740670
Stingl JC et al. Protocol for minimizing the risk of metachronous adenomas of the colorectum with green tea extract (MIRACLE): a randomised controlled trial of green tea extract versus placebo for nutriprevention of metachronous colon adenomas in the elderly population. 2011 BMC Cancer pmid:21851602
Bhattacharjee A et al. Deposition of stearate-oleate rich seed fat in Mangifera indica is mediated by a FatA type acyl-ACP thioesterase. 2011 Phytochemistry pmid:21130480
Yuan H et al. Stearic acid-g-chitosan polymeric micelle for oral drug delivery: in vitro transport and in vivo absorption. 2011 Mol. Pharm. pmid:21138243
Krogmann A et al. Inflammatory response of human coronary artery endothelial cells to saturated long-chain fatty acids. 2011 Microvasc. Res. pmid:21112343
Andaloussi SE et al. Application of PepFect peptides for the delivery of splice-correcting oligonucleotides. 2011 Methods Mol. Biol. pmid:21053143
Göker M et al. Complete genome sequence of the thermophilic sulfur-reducer Desulfurobacterium thermolithotrophum type strain (BSA(T)) from a deep-sea hydrothermal vent. 2011 Stand Genomic Sci pmid:22675590
Chaturvedi K et al. Floating matrix dosage form for propranolol hydrochloride based on gas formation technique: development and in vitro evaluation. 2010 Oct-Dec Sci Pharm pmid:21179326
Terekhova EA et al. [Stearic acid methyl ether: a new extracellular metabolite of the obligate methylotrophic bacterium Methylophilus quaylei]. 2010 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:20391761
Kristó K et al. Effect of lubricant on spreading of coating liquid on surface of tablets containing pancreatin. 2010 Jul-Aug Pharm Dev Technol pmid:19772392
Badawy SI et al. Effect of spray-dried mannitol on the performance of microcrystalline cellulose-based wet granulated tablet formulation. 2010 Jul-Aug Pharm Dev Technol pmid:20088677
Kaur G et al. Chitosan-carboxymethyl tamarind kernel powder interpolymer complexation: investigations for colon drug delivery. 2010 Jan-Mar Sci Pharm pmid:21179370
Stanisz B et al. Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. 2010 Jan-Feb Acta Pol Pharm pmid:20210086
Aburahma MH et al. Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid. 2010 Apr-Jun Sci Pharm pmid:21179352
Singh B et al. Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride. 2010 Apr-Jun Sci Pharm pmid:21179349
Chen Y et al. A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. 2010 Appl Spectrosc pmid:20925991
Mukherjee S et al. Stearic acid delivery to corneum from a mild and moisturizing cleanser. 2010 J Cosmet Dermatol pmid:20883293
Fang X et al. Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. 2010 BMC Syst Biol pmid:21092312
Rawat MK et al. Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. 2010 Ther Deliv pmid:22816120
Westerbacka J et al. Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. 2010 Gastroenterology pmid:20600015
Renaville B et al. Plasma and follicular fluid fatty acid profiles in dairy cows. 2010 Reprod. Domest. Anim. pmid:19055554
Liu TY and Lin YL Novel pH-sensitive chitosan-based hydrogel for encapsulating poorly water-soluble drugs. 2010 Acta Biomater pmid:19819354
Rajab M et al. Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid. 2010 Pharmazie pmid:20225651
Araújo J et al. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. 2010 Int J Pharm pmid:20362042
Kiss H et al. Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). 2010 Stand Genomic Sci pmid:21304711
Bender K et al. Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. 2010 Reproduction pmid:20385782
Pedersen PJ et al. Liposomal formulation of retinoids designed for enzyme triggered release. 2010 J. Med. Chem. pmid:20405849
Jain S et al. Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. 2010 J Young Pharm pmid:21264091
Naumova EA et al. Influence of individual saliva secretion on fluoride bioavailability. 2010 Open Dent J pmid:21221176
Sun H et al. Complete genome sequence of Desulfarculus baarsii type strain (2st14). 2010 Stand Genomic Sci pmid:21304732
Pennick G et al. Superior effect of isostearyl isostearate on improvement in stratum corneum water permeability barrier function as examined by the plastic occlusion stress test. 2010 Int J Cosmet Sci pmid:20642769
Zhu SH et al. [Study on the chemical constituents of Dichrocephala integrifolia]. 2010 Zhong Yao Cai pmid:20518304
Wieder DR and Pattimakiel L Examining the efficacy, safety, and patient acceptability of the combined contraceptive vaginal ring (NuvaRing). 2010 Int J Womens Health pmid:21151688
Manickam E et al. Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. 2010 Lipids Health Dis pmid:20525346
Luan L et al. [Studies on the chemical constituents of extract with water from Forsythia suspensa]. 2010 Zhong Yao Cai pmid:20575415
Remya K et al. Formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets. 2010 J Young Pharm pmid:21042477
Contreras GA et al. Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. 2010 J. Dairy Sci. pmid:20494158
Karande AD et al. In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. 2010 Int J Pharm pmid:20558264
Rao KS and Srinivas K RP-HPLC Method for the Determination of Losartan Potassium and Ramipril in Combined Dosage Form. 2010 Indian J Pharm Sci pmid:20582199
Keny RV et al. Formulation and evaluation of rizatriptan benzoate mouth disintegrating tablets. 2010 Indian J Pharm Sci pmid:20582194
Eftaiha AF et al. Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum. 2010 Mar Drugs pmid:20559494
Normand-Lauzière F et al. Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects. 2010 PLoS ONE pmid:20532041
Rivera CA et al. Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis. 2010 BMC Gastroenterol pmid:20509914
Harvey KA et al. Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. 2010 J. Lipid Res. pmid:20852092
Blanco M and Peguero A Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. 2010 J Pharm Biomed Anal pmid:20044229
Saravanakumari P and Mani K Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. 2010 Bioresour. Technol. pmid:20637606
Invernizzi G et al. Sustained upregulation of stearoyl-CoA desaturase in bovine mammary tissue with contrasting changes in milk fat synthesis and lipogenic gene networks caused by lipid supplements. 2010 Funct. Integr. Genomics pmid:20607344
Chon B et al. Shell and ligand-dependent blinking of CdSe-based core/shell nanocrystals. 2010 Phys Chem Chem Phys pmid:20607188
Lin SY et al. Solid-state transformation of different gabapentin polymorphs upon milling and co-milling. 2010 Int J Pharm pmid:20561572
Bunn RC et al. Palmitate and insulin synergistically induce IL-6 expression in human monocytes. 2010 Cardiovasc Diabetol pmid:21054880
Asai T and Fujimoto Y Cyclic fatty acyl glycosides in the glandular trichome exudate of Silene gallica. 2010 Phytochemistry pmid:20541780
Jun HY et al. Long residence time of ultrasound microbubbles targeted to integrin in murine tumor model. 2010 Acad Radiol pmid:19815430
Lai TY et al. Alterations in serum fatty acid concentrations and desaturase activities in Bietti crystalline dystrophy unaffected by CYP4V2 genotypes. 2010 Invest. Ophthalmol. Vis. Sci. pmid:19797200
Thomas CP et al. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. 2010 J. Biol. Chem. pmid:20061396