stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Obesity, Abdominal D056128 3 associated lipids
Atherosclerosis D050197 85 associated lipids
Metabolic Syndrome D024821 44 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Weight Gain D015430 101 associated lipids
Reperfusion Injury D015427 65 associated lipids
Zellweger Syndrome D015211 39 associated lipids
Yaws D015001 4 associated lipids
Whooping Cough D014917 6 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Urticaria D014581 13 associated lipids
Urethritis D014526 9 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Tremor D014202 15 associated lipids
Thrombosis D013927 49 associated lipids
Tenosynovitis D013717 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Spinal Cord Injuries D013119 34 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
WIRTH JC and ANAND SR THE FATTY ACIDS OF TRICHOPHYTON RUBRUM. 1964 Can. J. Microbiol. pmid:14124857
PILZ W and HOERLEIN H [INVESTIGATIONS CONCERNING ENZYMES OF HUMAN BLOOD, VIII. THE POSSIBLE ROLE OF ARYLESTERASE I IN HUMAN FAT METABOLISM]. 1964 Hoppe-Seyler's Z. Physiol. Chem. pmid:14124985
BERGMANN ED et al. THIN-LAYER CHROMATOGRAPHY OF BETA-SITOSTERYL ESTERS. 1964 J. Chromatogr. pmid:14207024
WAIBEL PE and MRAZ FR CALCIUM, STRONTIUM AND PHOSPHORUS UTILIZATION BY CHICKS AS INFLUENCED BY NUTRITIONAL AND ENDOCRINE VARIATIONS. 1964 J. Nutr. pmid:14210023
VAHOUNY GV et al. MICELLAR-SOLUBILIZED SUBSTRATES AND CHOLESTEROL ESTERASE ACTIVITY IN VITRO. 1964 Arch. Biochem. Biophys. pmid:14211570
MACDONALD I and BARRY PJ CHANGES IN THE FATTY ACID PATTERN OF THE ADIPOSE TISSUE OF OBESE SUBJECTS WHILE ON A REDUCING REGIMEN. 1964 Am. J. Clin. Nutr. pmid:14212750
KOEHLER WR et al. A METHOD FOR SEPARATING SATURATED FATTY ACID ESTERS FROM UNSATURATED ESTERS FOR GAS CHROMATOGRAPHIC ANALYSIS. 1964 Anal. Biochem. pmid:14213999
VROMAN L and LUKOSEVICIUS A ELLIPSOMETER RECORDINGS OF CHANGES IN OPTICAL THICKNESS OF ADSORBED FILMS ASSOCIATED WITH SURFACE ACTIVATION OF BLOOD CLOTTING. 1964 Nature pmid:14236308
PORTMAN OW and SUGANO M FACTORS INFLUENCING THE LEVEL AND FATTY ACID SPECIFICITY OF THE CHOLESTEROL ESTERIFICATION ACTIVITY IN HUMAN PLASMA. 1964 Arch. Biochem. Biophys. pmid:14236639
SHELTON DC et al. THE UPTAKE AND DISTRIBUTION OF STEARIC ACID BY SUBCELLULAR COMPONENTS OF INTESTINAL MUCOSA. 1964 Am. J. Clin. Nutr. pmid:14240483
JACKSON HD et al. FORMATION OF KETONE BODIES FROM LONG-CHAIN FATTY ACIDS IN RUMEN EPITHELIUM AND LIVER FROM KETOTIC SHEEP. 1964 Arch. Biochem. Biophys. pmid:14240563
MOORE JH and WILLIAMS D THE RELATIONSHIP BETWEEN THE LINOLEIC ACID CONTENT OF THE DIET, THE FATTY ACID COMPOSITION OF THE PLASMA PHOSPHOLIPIDS AND THE DEGREE OF AORTIC ATHEROSIS IN EXPERIMENTAL RABBITS. 1964 Br. J. Nutr. pmid:14241591
MALJKOVIC I [A CASE OF CHRONIC OCCUPATIONAL POISONING WITH LEAD STEARATE AND CARBONATE]. 1964 Arh Hig Rada Toksikol pmid:14342211
HIRSHFIELD IN and KORITZ SB THE STIMULATION OF PREGNENOLONE SYNTHESIS IN THE LARGE PARTICLES FROM RAT ADRENALS BY SOME AGENTS WHICH CAUSE MITOCHONDRIAL SWELLING. 1964 Biochemistry pmid:14269324
POLAN CE et al. BIOHYDROGENATION OF UNSATURATED FATTY ACIDS BY RUMEN BACTERIA. 1964 J. Bacteriol. pmid:14219019
AARONSON S A ROLE FOR A STEROL AND A STEROL PRECURSOR IN THE BACTERIUM RHODOPSEUDOMONAS PALUSTRIS. 1964 J. Gen. Microbiol. pmid:14247747
HULANICKA D et al. LIPID METABOLISM OF EUGLENA GRACILIS. 1964 J. Biol. Chem. pmid:14216427
FULCO AJ et al. THE BIOSYNTHESIS OF DELTA-9 AND DELTA-5-MONOSATURATED FATTY ACIDS BY BACTERIA. 1964 J. Biol. Chem. pmid:14167618
GOTO Y et al. EXPERIMENTAL STUDY ON THE LIPID METABOLISM IN THE HEART MUSCLE. 1964 Jpn. Circ. J. pmid:14167720
ELSBACH P COMPARISON OF UPTAKE OF PALMITIC, STEARIC, OLEIC AND LINOLEIC ACID BY POLYMORPHONUCLEAR LEUKOCYTES. 1964 Biochim. Biophys. Acta pmid:14124760