stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Breast Neoplasms D001943 24 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Neoplasms D008113 8 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Zhang JW et al. [Studies on the chemical constituents of Toricellia angulata var. intermedia]. 2010 Zhong Yao Cai pmid:21434432
Daraghmeh N et al. Preparation and characterization of a novel co-processed excipient of chitin and crystalline mannitol. 2010 AAPS PharmSciTech pmid:21052880
Patra S et al. In vitro evaluation of domperidone mouth dissolving tablets. 2010 Indian J Pharm Sci pmid:21969764
Akpa MM et al. Inhibition of insulin and T3-induced fatty acid synthase by hexanoate. 2010 Lipids pmid:20811782
Lin YK et al. Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery. 2010 Int J Nanomedicine pmid:20309398
Shen J et al. Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: Improving in vivo ocular distribution. 2010 Int J Pharm pmid:20934499
Varshosaz J et al. Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. 2010 Int J Prev Med pmid:21566772
Alizadeh M et al. The effect of hypocaloric diet enriched in legumes with or without L-arginine and selenium on anthropometric measures in central obese women. 2010 J Res Med Sci pmid:21526106
Nouri A et al. Effect of process control agent on the porous structure and mechanical properties of a biomedical Ti-Sn-Nb alloy produced by powder metallurgy. 2010 Acta Biomater pmid:19815096
Liu RS and Tang YJ Quantitative analysis for the effect of plant oil and fatty acid on Tuber melanosporum culture by uniform design combined with partial least squares regression. 2010 Appl. Microbiol. Biotechnol. pmid:20473608
Sorek N et al. An S-acylation switch of conserved G domain cysteines is required for polarity signaling by ROP GTPases. 2010 Curr. Biol. pmid:20451389
Murate M et al. Phosphatidylglucoside forms specific lipid domains on the outer leaflet of the plasma membrane. 2010 Biochemistry pmid:20433166
Ohwoavworhua FO and Adelakun TA Non-wood Fibre Production of Microcrystalline Cellulose from Sorghum caudatum: Characterisation and Tableting Properties. 2010 Indian J Pharm Sci pmid:21188036
Zhou QT et al. Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach. 2010 Int J Pharm pmid:20435112
Cohn JS et al. Reduction in intestinal cholesterol absorption by various food components: mechanisms and implications. 2010 Atheroscler Suppl pmid:20439167
Pires de Souza FC et al. In vitro comparison of the radiopacity of cavity lining materials with human dental structures. 2010 J Conserv Dent pmid:20859477
Lyra A et al. Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes. 2010 BMC Gastroenterol pmid:20849659
Shishu VR et al. Development of taste masked oral formulation of ornidazole. 2010 Indian J Pharm Sci pmid:20838525
Gohel MC et al. Fabrication and Evaluation of Bi-layer Tablet Containing Conventional Paracetamol and Modified Release Diclofenac Sodium. 2010 Indian J Pharm Sci pmid:20838522
Phaechamud T et al. Preparation of Coated Valproic Acid and Sodium Valproate Sustained-release Matrix Tablets. 2010 Indian J Pharm Sci pmid:20838520
Yang X et al. In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. 2010 Drug Dev Ind Pharm pmid:20141448
Huthmacher C et al. Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. 2010 BMC Syst Biol pmid:20807400
Du YZ et al. Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: factors affecting the complexation. 2010 Int J Pharm pmid:20170716
Noguchi Y et al. Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice. 2010 PLoS ONE pmid:20706589
Baki G et al. Role of surface free energy and spreading coefficient in the formulation of active agent-layered pellets. 2010 Eur J Pharm Biopharm pmid:19931611
Maher AC et al. Women have higher protein content of beta-oxidation enzymes in skeletal muscle than men. 2010 PLoS ONE pmid:20700461
Bolton B and Halpern BP Orthonasal and retronasal but not oral-cavity-only discrimination of vapor-phase fatty acids. 2010 Chem. Senses pmid:20100787
Lu L et al. Near infrared spectroscopy of stearic acid adsorbed on montmorillonite. 2010 Spectrochim Acta A Mol Biomol Spectrosc pmid:20071218
Roblegg E et al. Development of lipophilic calcium stearate pellets using ibuprofen as model drug. 2010 Eur J Pharm Biopharm pmid:20080179
Pan PH et al. Stearic acid attenuates cholestasis-induced liver injury. 2010 Biochem. Biophys. Res. Commun. pmid:20036638
Do PT et al. The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. 2010 Plant Physiol. pmid:20841452
Prossnigg F et al. Packing behaviour of two predominant anionic phospholipids of bacterial cytoplasmic membranes. 2010 Biophys. Chem. pmid:20451316
Chitapanarux I et al. Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. 2010 Radiat Oncol pmid:20444243
Swanson EJ et al. Phospholipid-stabilized microbubble foam for injectable oxygen delivery. 2010 Langmuir pmid:20873807
Howell AB et al. Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. 2010 BMC Infect. Dis. pmid:20398248
Yasuda A et al. Self-organizing map analysis using multivariate data from theophylline powders predicted by a thin-plate spline interpolation. 2010 J Pharm Sci pmid:20845452
UÄŸurlu T et al. Effects of lubricants on binary direct compression mixtures. 2010 Drug Discov Ther pmid:22491169
Shaikh SA et al. Formulation and evaluation of s-(-)-amlodipine besylate and nebivolol hydrochloride tablets. 2010 J Adv Pharm Technol Res pmid:22247846
Tiwari G et al. Cyclodextrins in delivery systems: Applications. 2010 J Pharm Bioallied Sci pmid:21814436
Shidhaye SS et al. Buccal drug delivery of pravastatin sodium. 2010 AAPS PharmSciTech pmid:20300898
van den Berg SA et al. High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity. 2010 Nutr Metab (Lond) pmid:20346174
Xing Z et al. Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. 2010 Acta Biomater pmid:20226284
Choi JN et al. Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation. 2010 J. Agric. Food Chem. pmid:20225861
Desando MA et al. Proton magnetic relaxation and the aggregation of n-octylammonium n-octadecanoate surfactant in deuterochloroform solution. 2010 J Colloid Interface Sci pmid:20223468
Xing Z et al. The fabrication of novel nanobubble ultrasound contrast agent for potential tumor imaging. 2010 Nanotechnology pmid:20220227
Li Y et al. Preparation and characterization of coverage-controlled CaCO3 nanoparticles. 2010 J Colloid Interface Sci pmid:20202642
Salbu L et al. Direct compression behavior of low- and high-methoxylated pectins. 2010 AAPS PharmSciTech pmid:20013080
Romanowicz L and Bańkowski E Sphingolipids of human umbilical cord vein and their alteration in preeclampsia. 2010 Mol. Cell. Biochem. pmid:20155487
Kordyukova LV et al. Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. 2010 Virology pmid:20006369
Abdel-Mottaleb MM et al. In vitro drug release mechanism from lipid nanocapsules (LNC). 2010 Int J Pharm pmid:20149853
Taneri F et al. In vitro and in vivo evaluation of oral tablet formulations prepared with ketoconazole and hydroxypropyl-beta-cyclodextrin. 2010 Drug Deliv pmid:20148713
Yoo HJ and HÃ¥kansson K Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. 2010 Anal. Chem. pmid:20704384
Yuan Y et al. A signal-on electrochemical probe-label-free aptasensor using gold-platinum alloy and stearic acid as enhancers. 2010 Biosens Bioelectron pmid:20708400
Yeop Han C et al. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. 2010 Diabetes pmid:19934003
Jian WX et al. [Detection and analysis on plasma metabolomics in patient with coronary heart disease of Xin-blood stasis syndrome pattern]. 2010 Zhongguo Zhong Xi Yi Jie He Za Zhi pmid:20815270
Gonzalez-Mira E et al. Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. 2010 Colloids Surf B Biointerfaces pmid:20719479
Chakraborty S et al. Utilization of adsorption technique in the development of oral delivery system of lipid based nanoparticles. 2010 Colloids Surf B Biointerfaces pmid:20728320
Tripathi B et al. Fortification of sorghum (Sorghum vulgare) and pearl millet (Pennisetum glaucum) flour with zinc. 2010 J Trace Elem Med Biol pmid:20685098
Raeside JI and Christie HL Diaryl dimers of estradiol and of estrone may be formed as major metabolites by mouse mammary glands. 2010 Biochem. Biophys. Res. Commun. pmid:20875396
Valencia-Chamorro SA et al. Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. 2010 J. Food Sci. pmid:21535515
Alshamsan A et al. Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. 2009 Jan-Feb Mol. Pharm. pmid:19053537
Snoeren TA et al. Multidisciplinary approach to unravelling the relative contribution of different oxylipins in indirect defense of Arabidopsis thaliana. 2009 J. Chem. Ecol. pmid:19798534
Atherton HJ et al. Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse. 2009 Mol. Syst. Biol. pmid:19357638
Sahoo RR and Biswas SK Frictional response of fatty acids on steel. 2009 J Colloid Interface Sci pmid:19232636
Martínez-Force E et al. Influence of specific fatty acids on the asymmetric distribution of saturated fatty acids in sunflower (Helianthus annuus L.) triacylglycerols. 2009 J. Agric. Food Chem. pmid:19166295
Chen JJ et al. seco-Abietane diterpenoids, a phenylethanoid derivative, and antitubercular constituents from Callicarpa pilosissima. 2009 J. Nat. Prod. pmid:19193025
Peters GH et al. Effects of fatty acid inclusion in a DMPC bilayer membrane. 2009 J Phys Chem B pmid:19195101
Sugisawa K et al. Rapid quantitative analysis of magnesium stearate in pharmaceutical powders and solid dosage forms by atomic absorption: method development and application in product manufacturing. 2009 J Pharm Biomed Anal pmid:19195812
Tuomasjukka SS et al. Regio-distribution of stearic acid is not conserved in chylomicrons after ingestion of randomised, stearic acid-rich fat in a single meal. 2009 J. Nutr. Biochem. pmid:19195862
Roberts R et al. Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans. 2009 Diabetologia pmid:19252892
Asgary S et al. Evaluation of fatty acid content of some Iranian fast foods with emphasis on trans fatty acids. 2009 Asia Pac J Clin Nutr pmid:19713177
Gupta A et al. Difference in the lubrication efficiency of bovine and vegetable-derived magnesium stearate during tabletting. 2009 AAPS PharmSciTech pmid:19390976
Sakuradani E et al. Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4. 2009 Appl. Microbiol. Biotechnol. pmid:19415268
Chen JM et al. [Comparison of seed oil physicochemical characteristics among three cultivars of Jatropha curcas L]. 2009 Ying Yong Sheng Tai Xue Bao pmid:20353052
Kadotani A et al. Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19755671
Costa MC et al. The solid-liquid phase diagrams of binary mixtures of consecutive, even saturated fatty acids. 2009 Chem. Phys. Lipids pmid:19520067
Prajapati ST et al. Studies on formulation and in vitro evaluation of floating matrix tablets of domperidone. 2009 Indian J Pharm Sci pmid:20177450
Puzanowska-Tarasiewicz H et al. Spectroscopic and electrochemical analysis of psychotropic drugs. 2009 Indian J Pharm Sci pmid:20177449
Wei Y et al. Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells. 2009 Mol. Cell. Biochem. pmid:19444596
Fostok SF et al. Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus. 2009 BMC Complement Altern Med pmid:19917107
Evans LM et al. Stearate preferentially induces apoptosis in human breast cancer cells. 2009 Nutr Cancer pmid:19838949
Mukherjee S and Datta A Morphology and structural evolution in cobalt stearate Langmuir-Blodgett films. 2009 J Nanosci Nanotechnol pmid:19928206
Yarkala S et al. Role of excipients on N-oxide raloxifene generation from raloxifene-excipients binary mixtures. 2009 Chem. Pharm. Bull. pmid:19801885
Jayakumar OD et al. Water dispersible Fe3O4 nanoparticles carrying doxorubicin for cancer therapy. 2009 J Nanosci Nanotechnol pmid:19908532
Fujita M et al. Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine. 2009 Chem. Pharm. Bull. pmid:19801864
Ye YQ et al. Enhanced cytotoxicity of core modified chitosan based polymeric micelles for doxorubicin delivery. 2009 J Pharm Sci pmid:18563810
Gängler P et al. In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel. 2009 BMC Oral Health pmid:19799785
Hellemans KH et al. Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase. 2009 PLoS ONE pmid:19787047
Artwohl M et al. Fatty acids induce apoptosis in human smooth muscle cells depending on chain length, saturation, and duration of exposure. 2009 Atherosclerosis pmid:18597758
Cha KH et al. Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia. 2009 Arch. Pharm. Res. pmid:20091273
Bolhuis GK et al. Compaction properties of isomalt. 2009 Eur J Pharm Biopharm pmid:19327398
Staiger K et al. Protein kinase C iota mediates lipid-induced apoptosis of human coronary artery endothelial cells. 2009 Microvasc. Res. pmid:19327373
Alloatti A et al. Chemical evaluation of fatty acid desaturases as drug targets in Trypanosoma cruzi. 2009 Int. J. Parasitol. pmid:19249306
Ishikado A et al. Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells. 2009 Atherosclerosis pmid:19215923
Yang Y et al. Radial-position-controlled doping of CdS/ZnS core/shell nanocrystals: surface effects and position-dependent properties. 2009 Chemistry pmid:19206119
Durak D and Kalender Y Fine structure and chemical analysis of the metathoracic scent gland secretion in Graphosoma lineatum (Linnaeus, 1758) (Heteroptera, Pentatomidae). 2009 C. R. Biol. pmid:19200924
Nyadong L et al. Combining two-dimensional diffusion-ordered nuclear magnetic resonance spectroscopy, imaging desorption electrospray ionization mass spectrometry, and direct analysis in real-time mass spectrometry for the integral investigation of counterfeit pharmaceuticals. 2009 Anal. Chem. pmid:19453162
Meng W et al. A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial. 2009 Trials pmid:19419555
Brach Del Prever EM et al. UHMWPE for arthroplasty: past or future? 2009 J Orthop Traumatol pmid:19384628
Marvey BB Extrudate versus powder silica alumina as support for Re₂O₇ catalyst in the metathesis of seed oil-derivatives - a comparison. 2009 Int J Mol Sci pmid:19333442