stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Breast Neoplasms D001943 24 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Neoplasms D008113 8 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Ricci M et al. Growth and Dissolution of Calcite in the Presence of Adsorbed Stearic Acid. 2015 Langmuir pmid:26087312
Santos IC et al. Paired-ion electrospray ionization--triple quadrupole tandem mass spectrometry for quantification of anionic surfactants in waters. 2015 Talanta pmid:26078166
Rizzuti B et al. Fatty acid binding into the highest affinity site of human serum albumin observed in molecular dynamics simulation. 2015 Arch. Biochem. Biophys. pmid:26048999
Yi HX et al. Effect of anionic PEGylated polypeptide on gene transfection mediated by glycolipid conjugate micelles. 2015 Mol. Pharm. pmid:25490413
Leonardi A et al. Cationic solid lipid nanoparticles enhance ocular hypotensive effect of melatonin in rabbit. 2015 Int J Pharm pmid:25448580
Momoh MA et al. Influence of magnesium stearate on the physicochemical and pharmacodynamic characteristics of insulin-loaded Eudragit entrapped mucoadhesive microspheres. 2015 Drug Deliv pmid:24670092
Miyazaki Y et al. Dry Powder Coating using Planetary Centrifugal Mixer. 2015 J Pharm Pharm Sci pmid:26517137
Veselỳ M et al. Photocatalytic and Antimicrobial Activity of Printed Hybrid Titania/Silica Layers. 2015 J Nanosci Nanotechnol pmid:26716211
Li Y et al. Effects of sustained-release composite on the oxygen levels and sediment phosphorus fractions of an urban river in Shanghai. 2014 Sep-Oct Environ Technol pmid:25145170
Mu L et al. Erythrocyte saturated fatty acids and systemic inflammation in adults. 2014 Nov-Dec Nutrition pmid:25280420
Wu JX et al. Chemical imaging and solid state analysis at compact surfaces using UV imaging. 2014 Int J Pharm pmid:25445531
Haware RV et al. Application of multivariate methods to evaluate the functionality of bovine- and vegetable-derived magnesium stearate. 2014 J Pharm Sci pmid:24596131
Guo H et al. In vitro and in vivo study of Gal-OS self-assembled nanoparticles for liver-targeting delivery of doxorubicin. 2014 J Pharm Sci pmid:24549734
Lorenzo JM Changes on physico-chemical, textural, lipolysis and volatile compounds during the manufacture of dry-cured foal "cecina". 2014 Meat Sci. pmid:23916960
Carrero-Colón M et al. Mutations in SACPD-C result in a range of elevated stearic acid concentration in soybean seed. 2014 PLoS ONE pmid:24846334
Gebauer SK et al. Impact of stearic acid and oleic acid on hemostatic factors in the context of controlled diets consumed by healthy men. 2014 Eur J Clin Nutr pmid:24736679
Zhao X et al. Diet modulation is an effective complementary agent in preventing and treating breast cancer lung metastasis. 2014 Clin. Exp. Metastasis pmid:24832758
Aznar-Moreno JA et al. Sunflower (Helianthus annuus) long-chain acyl-coenzyme A synthetases expressed at high levels in developing seeds. 2014 Physiol Plant pmid:24102504
Liu J et al. Saturated fatty acids up-regulate COX-2 expression in prostate epithelial cells via toll-like receptor 4/NF-κB signaling. 2014 Inflammation pmid:24221358
Kushner J et al. A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes. 2014 J Pharm Sci pmid:24375069