stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Breast Neoplasms D001943 24 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Neoplasms D008113 8 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Muselík J et al. Influence of process parameters on content uniformity of a low dose active pharmaceutical ingredient in a tablet formulation according to GMP. 2014 Acta Pharm pmid:25296681
Tsukada G et al. Temperature triggered shape memory effect of transpolyisoprene-based polymer. 2014 J Endod pmid:25260740
Pandey P et al. Excipient-process interactions and their impact on tablet compaction and film coating. 2014 J Pharm Sci pmid:25223603
Kushner J and Schlack H Commercial scale validation of a process scale-up model for lubricant blending of pharmaceutical powders. 2014 Int J Pharm pmid:25152166
Rico JE et al. Compared with stearic acid, palmitic acid increased the yield of milk fat and improved feed efficiency across production level of cows. 2014 J. Dairy Sci. pmid:24342689
Petridis L et al. Spatial arrangement of organic compounds on a model mineral surface: implications for soil organic matter stabilization. 2014 Environ. Sci. Technol. pmid:24328330
Mandal S et al. Enhancement of survival of alginate-encapsulated Lactobacillus casei NCDC 298. 2014 J. Sci. Food Agric. pmid:24307185
Maghsoodi M Floating-pulsatile release multiparticulate system for chronopharmacotherapy: effect of some hydrophobic additives on the buoyancy and release behavior of particles. 2014 Drug Res (Stuttg) pmid:23950100
Gouk SW et al. Stearic acids at sn-1, 3 positions of TAG are more efficient at limiting fat deposition than palmitic and oleic acids in C57BL/6 mice. 2014 Br. J. Nutr. pmid:24286356
Eiras CE et al. Glycerine levels in the diets of crossbred bulls finished in feedlot: carcass characteristics and meat quality. 2014 Meat Sci. pmid:24211551
Liau CP et al. Preparation and characterization of polyhydroxybutyrate/polycaprolactone nanocomposites. 2014 ScientificWorldJournal pmid:24600329
Woo JO et al. Development of a controlled release of salicylic acid loaded stearic acid-oleic acid nanoparticles in cream for topical delivery. 2014 ScientificWorldJournal pmid:24578624
Yee JK et al. High oleic/stearic fatty-acid desaturation index in cord plasma from infants of mothers with gestational diabetes. 2014 J Perinatol pmid:24577432
Huang FC et al. Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. 2014 Appl. Environ. Microbiol. pmid:24242247
Sassa T et al. Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid. 2014 J. Lipid Res. pmid:24489110
Maretti E et al. Inhaled Solid Lipid Microparticles to target alveolar macrophages for tuberculosis. 2014 Int J Pharm pmid:24374224
Samanta AK et al. Energy-based analysis of cone milling process for the comminution of roller compacted flakes. 2014 Int J Pharm pmid:24374608
Doig M et al. Structure and friction of stearic acid and oleic acid films adsorbed on iron oxide surfaces in squalane. 2014 Langmuir pmid:24364665
Dou J et al. Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration. 2014 Colloids Surf B Biointerfaces pmid:24157590
Meulenaar J et al. Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling. 2014 J Pharm Sci pmid:24311366