| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Breast Neoplasms | D001943 | 24 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Insulinoma | D007340 | 28 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Liver Neoplasms | D008113 | 8 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jones RE and Plymate SR | Evidence for the regulation of fatty acid utilization in human sperm by docosahexaenoic acid. | 1988 | Biol. Reprod. | pmid:2905175 |
| Abbott AA et al. | A prospective randomized trial on efficacy of antibiotic prophylaxis in asymptomatic teeth with pulpal necrosis and associated periapical pathosis. | 1988 | Oral Surg. Oral Med. Oral Pathol. | pmid:3144686 |
| Takenaka T et al. | Effects of arachidonic acid and the other long-chain fatty acids on the membrane currents in the squid giant axon. | 1988 | J. Membr. Biol. | pmid:3147335 |
| Bach R et al. | Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine. | 1988 | Biochemistry | pmid:3166978 |
| Sanjurjo P et al. | Plasma fatty acid composition during the first week of life following feeding with human milk or formula. | 1988 | Acta Paediatr Scand | pmid:3354331 |
| Graham A et al. | Fatty acid specificity for the synthesis of triacylglycerol and phosphatidylcholine and for the secretion of very-low-density lipoproteins and lysophosphatidylcholine by cultures of rat hepatocytes. | 1988 | Biochem. J. | pmid:3355493 |
| Bonanome A and Grundy SM | Effect of dietary stearic acid on plasma cholesterol and lipoprotein levels. | 1988 | N. Engl. J. Med. | pmid:3362176 |
| Rosenberg IH and Schaefer EJ | Dietary saturated fatty acids and blood cholesterol. | 1988 | N. Engl. J. Med. | pmid:3362180 |
| Zanetti R and Catalá A | Lipid binding properties of fatty acid binding protein isolated from mouse liver. | 1988 | Acta Physiol Pharmacol Latinoam | pmid:3201993 |
| Sparace SA et al. | A preliminary analysis of Fatty Acid synthesis in pea roots. | 1988 | Plant Physiol. | pmid:16666088 |
| Horváth LI et al. | Exchange rates at the lipid-protein interface of myelin proteolipid protein studied by spin-label electron spin resonance. | 1988 | Biochemistry | pmid:2450570 |
| Loscalzo J et al. | Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. | 1987 Sep-Oct | Arteriosclerosis | pmid:3675304 |
| Shani J et al. | Efficacy of sustained-release radioprotective drugs in vivo. | 1987 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:2966504 |
| Kringsholm B and Christoffersen P | The nature and the occurrence of birefringent material in different organs in fatal drug addiction. | 1987 May-Jun | Forensic Sci. Int. | pmid:3036675 |
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| Fatemi SH et al. | The glycophospholipid anchor of Thy-1. Biosynthetic labeling experiments with wild-type and class E Thy-1 negative lymphomas. | 1987 | J. Biol. Chem. | pmid:2881925 |
| West AA et al. | The relationship between glycosyltransferase production and membrane fatty acid composition of Streptococcus sanguis NCTC 7865 grown in the presence of protonmotive force inhibitors. | 1987 | J. Gen. Microbiol. | pmid:2966234 |
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| Reddy TS and Bazan NG | Arachidonic acid, stearic acid, and diacylglycerol accumulation correlates with the loss of phosphatidylinositol 4,5-bisphosphate in cerebrum 2 seconds after electroconvulsive shock: complete reversion of changes 5 minutes after stimulation. | 1987 | J. Neurosci. Res. | pmid:2830409 |
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| DeGeorge JJ et al. | Acetylcholine stimulates selective liberation and re-esterification of arachidonate and accumulation of inositol phosphates and glycerophosphoinositol in C62B glioma cells. | 1987 | J. Biol. Chem. | pmid:3110145 |
| Morse DR et al. | Infectious flare-ups and serious sequelae following endodontic treatment: a prospective randomized trial on efficacy of antibiotic prophylaxis in cases of asymptomatic pulpal-periapical lesions. | 1987 | Oral Surg. Oral Med. Oral Pathol. | pmid:3112672 |
| Crost S et al. | Hormonal effects on mitochondrial respiration: potential role of endogenous lipolytic activities. | 1987 | Arch. Biochem. Biophys. | pmid:3113334 |
| Halát G et al. | Effects of incomplete ischemia and subsequent recirculation on free palmitate, stearate, oleate and arachidonate levels in lumbar and cervical spinal cord of rabbit. | 1987 | Gen. Physiol. Biophys. | pmid:3117617 |
| Hohl C and Rösen P | Arachidonic acid metabolism in isolated rat heart myocytes. | 1987 | Prog. Clin. Biol. Res. | pmid:3118380 |
| Taylor AJ et al. | An alternative explanation for the changes in erythrocyte fatty acids observed in diabetes mellitus. | 1987 | Clin. Chem. | pmid:3119255 |
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| Roughan PG et al. | Metabolism of exogenous long-chain fatty acids by spinach leaves. | 1987 | Arch. Biochem. Biophys. | pmid:3426240 |
| Habib NA et al. | Stearic acid and carcinogenesis. | 1987 | Br. J. Cancer | pmid:3689663 |
| Kaya K and Nohara K | Effect of di-n-octyl phthalate on fatty acid composition of phosphatidylcholine in Tetrahymena. | 1987 | Chem. Biol. Interact. | pmid:3690725 |
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| Seifert R et al. | Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3426598 |
| Bos CE et al. | Native starch in tablet formulations: properties on compaction. | 1987 | Pharm Weekbl Sci | pmid:3432037 |
| Nadai M et al. | [Correlation between in vitro dissolution characteristics of macrolide antibiotic tablets and bioavailability in man]. | 1987 | Yakugaku Zasshi | pmid:3437396 |
| Hasin Y et al. | Dietary lipid intake and myocardial electrophysiology. | 1987 | Isr. J. Med. Sci. | pmid:3440741 |
| Cutler RR et al. | The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. | 1987 | Tubercle | pmid:3448797 |
| Matsui MS and Jeffrey AM | Fatty acid modification of C3H 10T 1/2 fibroblast cells: changes in benzo(a)pyrene metabolism and phorbol ester binding. | 1987 | Cancer Res. | pmid:3471326 |
| Habib NA et al. | Desaturation-producing factor present in the tissue, blood, and urine of cancer patients. | 1987 | Cancer Detect. Prev. | pmid:3568009 |
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| Emken EA et al. | Metabolism in humans of cis-12,trans-15-octadecadienoic acid relative to palmitic, stearic, oleic and linoleic acids. | 1987 | Lipids | pmid:3306237 |
| Dinman BD | Aluminum in the lung: the pyropowder conundrum. | 1987 | J Occup Med | pmid:3316541 |
| Hattori T et al. | Membrane phospholipid composition and membrane fluidity of human brain tumour: a spin label study. | 1987 | Neurol. Res. | pmid:2883605 |
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