stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Breast Neoplasms D001943 24 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Bacterial Infections D001424 21 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Neoplasms D008113 8 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Heimdahl A and Nord CE Influence of erythromycin on the normal human flora and colonization of the oral cavity, throat and colon. 1982 Scand. J. Infect. Dis. pmid:7071527
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Akesson B Content of phospholipids in human diets studied by the duplicate-portion technique. 1982 Br. J. Nutr. pmid:7066286
Królikowska-Prasał I and Zakrzewska-Grzycka T Histochemical studies of the liver in acute and chronic lead stearate poisoning. 1981 Ann Univ Mariae Curie Sklodowska Med pmid:7052786
Jacques NA Relationship between cyclopropane synthetase and the formation of cyclopropane fatty acids by Proteus vulgaris grown under various respiratory conditions. 1982 J. Gen. Microbiol. pmid:7045282
Aprahamian SA et al. Comparative studies on the kinetic parameters and product analyses of chicken and rat liver and yeast fatty acid synthetase. 1982 Comp. Biochem. Physiol., B pmid:7044669
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RÃ¥dberg T et al. Metabolic studies in gestational diabetic women during contraceptive treatment: effects on glucose tolerance and fatty acid composition of serum lipids. 1982 Gynecol. Obstet. Invest. pmid:7035304
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Stein Y et al. Intralysosomal hydrolysis of cholesterol esters of varying fatty acid composition in cultured human skin fibroblasts. 1978 Biochim. Biophys. Acta pmid:698242
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Sobel JD et al. Legionella bozemanii. Still another cause of pneumonia. 1983 JAMA pmid:6854903
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Chapkin RS et al. Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis. 1983 J. Lab. Clin. Med. pmid:6833842
Edwards EK and Edwards EK Allergic reaction to triethanolamine stearate in a sunscreen. 1983 Cutis pmid:6831931
Pethick DW et al. The metabolism of circulating non-esterified fatty acids by the whole animal, hind-limb muscle and uterus of pregnant ewes. 1983 Br. J. Nutr. pmid:6821682
Oriel JD et al. Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. 1982 Oct-Dec Sex Transm Dis pmid:6821502
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McGimpsey JG et al. Comparison of serum erythromycin concentration following administration of 100 mg erythromycin ethyl succinate intramuscularly and 500 mg erythromycin stearate orally. 1981 Int J Oral Surg pmid:6807878
Hong SL and Deykin D Activation of phospholipases A2 and C in pig aortic endothelial cells synthesizing prostacyclin. 1982 J. Biol. Chem. pmid:6806265
Walsh C et al. Arachidonate metabolism by neutrophils. 1981 Prog. Lipid Res. pmid:6804984
Moore KH et al. beta-Hydroxy fatty acid production by ischemic rabbit heart. 1982 J. Clin. Invest. pmid:6799549
Yamauchi T et al. Thermal adaptation of Tetrahymena membranes with special reference to mitochondria. Role of cardiolipin in fluidity of mitochondrial membranes. 1981 Biochim. Biophys. Acta pmid:6797472
Bonini de Romanelli IC et al. Phosphatidic acid, phosphatidylinositol, phosphatidylserine and cardiolipin in the course of early embryonic development. Fatty acid composition and content in whole toad embryos and in mitochondrial fractions. 1981 Biochim. Biophys. Acta pmid:6791698
Broekman MJ et al. Fatty acid composition of phosphatidylinositol and phosphatidic acid in stimulated platelets. Persistence of arachidonyl-stearyl structure. 1981 J. Biol. Chem. pmid:6790536
Abumrad NA et al. Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. 1984 J. Biol. Chem. pmid:6746632
Greenberg DS et al. Fatty acid composition of lizard tissue lipids and the effects of estradiol on serum free fatty acids. 1984 Comp. Biochem. Physiol., B pmid:6744817
Kemp P et al. The hydrogenation of some cis- and trans-octadecenoic acids to stearic acid by a rumen Fusocillus sp. 1984 Br. J. Nutr. pmid:6743636
Pediconi MF and Rodríguez de Turco EB Free fatty acid content and release kinetics as manifestations of cerebral lateralization in mouse brain. 1984 J. Neurochem. pmid:6726237