stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Relapsing Fever D012061 3 associated lipids
Infertility D007246 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Chancroid D002602 4 associated lipids
Yaws D015001 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Foreign Bodies D005547 5 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bronchitis D001991 6 associated lipids
Whooping Cough D014917 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
Gonorrhea D006069 7 associated lipids
Leprosy D007918 8 associated lipids
Liver Neoplasms D008113 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Urethritis D014526 9 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Amnesia D000647 12 associated lipids
Otitis Media D010033 12 associated lipids
Rosacea D012393 13 associated lipids
Urticaria D014581 13 associated lipids
Tremor D014202 15 associated lipids
Olfaction Disorders D000857 17 associated lipids
Ischemia D007511 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Lymphoma D008223 18 associated lipids
Erectile Dysfunction D007172 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Anderson EK et al. Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. 2012 Arterioscler. Thromb. Vasc. Biol. pmid:22556332
Visioli F et al. Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response. 2012 Front Physiol pmid:22393325
Qu J et al. Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. 2012 Biotechnol Biofuels pmid:22377043
Som I et al. Status of surfactants as penetration enhancers in transdermal drug delivery. 2012 J Pharm Bioallied Sci pmid:22368393
Al-Ghamdi AF et al. Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. 2012 Chem Cent J pmid:22353684
Quintela M et al. Estimation of the uncertainty associated with the results based on the validation of chromatographic analysis procedures: application to the determination of chlorides by high performance liquid chromatography and of fatty acids by high resolution gas chromatography. 2012 J Chromatogr A pmid:22227361
Ghadiri M et al. Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size. 2012 Int J Pharm pmid:22227603
Borbon IA et al. Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1. 2012 Pharmacol. Biochem. Behav. pmid:22202649
Scalia S et al. Preparation and in vitro evaluation of salbutamol-loaded lipid microparticles for sustained release pulmonary therapy. 2012 J Microencapsul pmid:22208706
Duong CT and Roper MG A microfluidic device for the automated derivatization of free fatty acids to fatty acid methyl esters. 2012 Analyst pmid:22166918
Imae R et al. LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice. 2012 J. Lipid Res. pmid:22172515
Becker S et al. Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity. 2012 Cancer Biother. Radiopharm. pmid:22149684
Ghanam RH et al. Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. 2012 Front Microbiol pmid:22363329
Rozema E et al. Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. 2012 Evid Based Complement Alternat Med pmid:22675394
Severino P et al. Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. 2012 J Drug Deliv pmid:22175030
Imarisio C et al. Adenosine A(2a) receptor stimulation prevents hepatocyte lipotoxicity and non-alcoholic steatohepatitis (NASH) in rats. 2012 Clin. Sci. pmid:22439844
Rojas J and Kumar V Effect of silicification on the tableting performance of cellulose ii: a novel multifunctional excipient. 2012 Chem. Pharm. Bull. pmid:22689398
Griffith EC et al. Hydrophobic collapse of a stearic acid film by adsorbed l-phenylalanine at the air-water interface. 2012 J Phys Chem B pmid:22691061
Harvey KA et al. Trans fatty acids: induction of a pro-inflammatory phenotype in endothelial cells. 2012 Lipids pmid:22684911
Mekhail GM et al. Anticancer effect of atorvastatin nanostructured polymeric micelles based on stearyl-grafted chitosan. 2012 Int. J. Biol. Macromol. pmid:22652220
Feugmo CG et al. Towards modelling the vibrational signatures of functionalized surfaces: carboxylic acids on H-Si(111) surfaces. 2012 J Phys Condens Matter pmid:22394578
Tumen I et al. A therapeutic approach for wound healing by using essential oils of cupressus and juniperus species growing in Turkey. 2012 Evid Based Complement Alternat Med pmid:21941588
Watanabe Y et al. The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation. 2012 Diabetes pmid:22396206
Yavuz B et al. An overview on dry eye treatment: approaches for cyclosporin a delivery. 2012 ScientificWorldJournal pmid:22619624
Bonaduce I et al. New insights into the ageing of linseed oil paint binder: a qualitative and quantitative analytical study. 2012 PLoS ONE pmid:23166642
Chu BB et al. [XANES study of lead speciation in duckweed]. 2012 Guang Pu Xue Yu Guang Pu Fen Xi pmid:23016367
Pijls BG et al. Differences in long-term fixation between mobile-bearing and fixed-bearing knee prostheses at ten to 12 years' follow-up: a single-blinded randomised controlled radiostereometric trial. 2012 J Bone Joint Surg Br pmid:23015562
Guzzi R et al. Dynamics and binding affinity of spin-labeled stearic acids in β-lactoglobulin: evidences from EPR spectroscopy and molecular dynamics simulation. 2012 J Phys Chem B pmid:22950964
de Jong S et al. A semipermanent coating for preventing protein adsorption at physiological pH in kinetic capillary electrophoresis. 2012 Electrophoresis pmid:22899267
Dziewulska A et al. Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle. 2012 Mol. Membr. Biol. pmid:22881371
Zhang WY et al. Chronic unpredictable mild stress affects myocardial metabolic profiling of SD rats. 2012 J Pharm Biomed Anal pmid:22658902
Tuli RA et al. Studies on the effect of the size of polycaprolactone microspheres for the dispersion of salbutamol sulfate from dry powder inhaler formulations. 2012 Pharm. Res. pmid:22584947
Itoh Y and Hasegawa T Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. 2012 J Phys Chem A pmid:22551093
Suo T et al. Fixed-point and stratified analysis of the fine structure and composition of five gallstones with Fourier transform infrared (FT-IR) specular reflection spectroscopy. 2012 Microsc. Res. Tech. pmid:21809418
Mai K et al. Rosiglitazone increases fatty acid Δ9-desaturation and decreases elongase activity index in human skeletal muscle in vivo. 2012 Metab. Clin. Exp. pmid:21741058
Dobrzyn P et al. Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation. 2012 Mitochondrion pmid:21664496
Wang Z et al. Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling. 2012 Br. J. Nutr. pmid:21733316
Foster SP and Anderson KG Synthetic rates of key stored fatty acids in the biosynthesis of sex pheromone in the moth Heliothis virescens. 2012 Insect Biochem. Mol. Biol. pmid:22982110
Wang L et al. Effect of rare Earth ions on the properties of composites composed of ethylene vinyl acetate copolymer and layered double hydroxides. 2012 PLoS ONE pmid:22693627
Wong RH et al. Chronic effects of a wild green oat extract supplementation on cognitive performance in older adults: a randomised, double-blind, placebo-controlled, crossover trial. 2012 Nutrients pmid:22690320
Bederman I et al. Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:22679004
Meka VS et al. Design and in vitro evaluation of effervescent gastric floating drug delivery systems of propanolol HCl. 2012 Invest Clin pmid:22524109
Lalloo AK et al. Decoupling the role of image size and calorie intake on gastric retention of swelling-based gastric retentive formulations: pre-screening in the dog model. 2012 Int J Pharm pmid:22546295
Bevilacqua A et al. Selection of Yeasts as Starter Cultures for Table Olives: A Step-by-Step Procedure. 2012 Front Microbiol pmid:22666220
Chakradhar RP and Dinesh Kumar V Water-repellent coatings prepared by modification of ZnO nanoparticles. 2012 Spectrochim Acta A Mol Biomol Spectrosc pmid:22575349
Shah KU and Khan GM Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. 2012 ScientificWorldJournal pmid:22649325
Agostini F et al. Supercritical extraction from vinification residues: fatty acids, α-tocopherol, and phenolic compounds in the oil seeds from different varieties of grape. 2012 ScientificWorldJournal pmid:22593706
Guillon A et al. Pulmonary delivery of dry powders to rats: tolerability limits of an intra-tracheal administration model. 2012 Int J Pharm pmid:22609125
Schrank S et al. Ibuprofen-loaded calcium stearate pellets: drying-induced variations in dosage form properties. 2012 AAPS PharmSciTech pmid:22552931
Loutelier-Bourhis C et al. Mechanistic study of maleic anhydride grafting onto fatty double bonds using mass spectrometry. 2012 Rapid Commun. Mass Spectrom. pmid:22555920