stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| LEAT WM | FATTY ACID COMPOSITION OF THE SERUM LIPIDS OF PIGS GIVEN DIFFERENT AMOUNTS OF LINOLEIC ACID. | 1963 | Biochem. J. | pmid:14097364 |
| Dudley DT et al. | Depletion of arachidonic acid from GH3 cells. Effects on inositol phospholipid turnover and cellular activation. | 1987 | Biochem. J. | pmid:3120699 |
| Crosby T et al. | Identification of ecdysone 22-long-chain fatty acyl esters in newly laid eggs of the cattle tick Boophilus microplus. | 1986 | Biochem. J. | pmid:3030275 |
| GLASCOCK RF and REINIUS LR | Studies on the origin of milk fat. 1. The location of tritium in stearic acid produced by the catalytic addition of tritium to elaidic acid. | 1956 | Biochem. J. | pmid:13315207 |
| COOKE NJ et al. | The branched-chain fatty acids of mutton fat. 3. The isolation of 16-methylheptadecanoic acid (isostearic acid). | 1956 | Biochem. J. | pmid:13363830 |
| DAWSON RM | The labelling of ram semen in vivo with radioactive phosphate and [carboxy-14C] stearic acid. | 1958 | Biochem. J. | pmid:13522653 |
| Bruce JS and Salter AM | Metabolic fate of oleic acid, palmitic acid and stearic acid in cultured hamster hepatocytes. | 1996 | Biochem. J. | pmid:8670161 |
| Hasegawa K et al. | Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH. | 2008 | Biochem. J. | pmid:18637792 |
| Bolton P and Harwood JL | Fatty acid biosynthesis by a particulate preparation from germinating pea. | 1977 | Biochem. J. | pmid:579600 |
| Véret J et al. | Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells. | 2011 | Biochem. J. | pmid:21592087 |
| Yamamoto A and Kawashima Y | Perfluorodecanoic acid enhances the formation of oleic acid in rat liver. | 1997 | Biochem. J. | pmid:9230124 |
| Foot M et al. | Some properties, including the substrate in vivo, of the delta 9-desaturase in Micrococcus cryophilus. | 1983 | Biochem. J. | pmid:6847622 |
| Zhao H and Hardy RW | Long-chain saturated fatty acids induce annexin II translocation to detergent-resistant membranes. | 2004 | Biochem. J. | pmid:15099193 |
| Veit M et al. | Cytoplasmic tail length influences fatty acid selection for acylation of viral glycoproteins. | 1996 | Biochem. J. | pmid:8761467 |
| Agarwal HC and Nair AM | Studies on the cholesterol ester hydrolase of Trogoderma (Coleoptera). | 1976 | Biochem. J. | pmid:962852 |
| Schlame M et al. | Relationship between lipid saturation and lipid-protein interaction in liver mitochondria modified by catalytic hydrogenation with reference to cardiolipin molecular species. | 1990 | Biochem. J. | pmid:2154183 |
| Russell NJ and Harwood JL | Changes in the acyl lipid composition of photosynthetic bacteria grown under photosynthetic and non-photosynthetic conditions. | 1979 | Biochem. J. | pmid:115463 |
| Sanchez J et al. | Lipase-induced alterations of fatty acid synthesis by subcellular fractions from germinating pea (Pisum sativum L.). | 1982 | Biochem. J. | pmid:7115342 |
| Jordan BR and Harwood JL | Fatty acid elongation by a particulate fraction from germinating pea. | 1980 | Biochem. J. | pmid:7283974 |
| Faas FH and Carter WJ | Fatty-acid desaturation and microsomal lipid fatty-acid composition in experimental hyperthyroidism. | 1981 | Biochem. J. | pmid:7305962 |
| NOBLE RC and MOORE JH | FURTHER STUDIES ON THE LIPID METABOLISM OF THE NORMAL AND VITAMIN B-12 DEFICIENT CHICK EMBRYO. | 1965 | Biochem. J. | pmid:14333549 |
| GLASCOCK RF and REINIUS LR | Location of tritium in stearic acid produced by catalytic tritiation of elaidic acid. | 1954 | Biochem. J. | pmid:13230049 |
| Walker KA and Harwood JL | Localization of chloroplastic fatty acid synthesis de novo in the stroma. | 1985 | Biochem. J. | pmid:3994672 |
| Light ND and Bailey AJ | Polymeric C-terminal cross-linked material from type-I collagen. A modified method for purification, anomalous behaviour on gel filtration, molecular weight estimation, carbohydrate content and lipid content. | 1980 | Biochem. J. | pmid:7458897 |
| Cardoso CM and De Meis L | Modulation by fatty acids of Ca2+ fluxes in sarcoplasmic-reticulum vesicles. | 1993 | Biochem. J. | pmid:7504458 |
| Griffiths G et al. | The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. | 1985 | Biochem. J. | pmid:4052051 |
| Trinchera M et al. | Recycling of glucosylceramide and sphingosine for the biosynthesis of gangliosides and sphingomyelin in rat liver. | 1990 | Biochem. J. | pmid:2241913 |
| Doering TL et al. | The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols. | 1994 | Biochem. J. | pmid:8192662 |
| McIlhinney RA and McGlone K | Evidence for a non-myristoylated pool of the 80 kDa protein kinase C substrate of rat brain. | 1990 | Biochem. J. | pmid:2244873 |
| Giudici TA et al. | Methylmalonic and propionic acidemias: lipid profiles of normal and affected human skin fibroblasts incubated with [1-14C]propionate. | 1986 | Biochem. Med. Metab. Biol. | pmid:2872907 |
| Lurie E et al. | N-(2-hydroxybenzyl)-omega-amino carbonic acids and their derivatives as tools for biochemical and biophysical investigations. | 1993 | Biochem. Mol. Biol. Int. | pmid:8358340 |
| Melik-Nubarov NS et al. | Interaction of hydrophobized antiviral antibodies with influenza virus infected MDCK cells. | 1993 | Biochem. Mol. Biol. Int. | pmid:8508145 |
| Ohyama H et al. | Age-related differences in synaptosomal membrane fluidity. | 1995 | Biochem. Mol. Biol. Int. | pmid:8653075 |
| Croxtall JD et al. | Tamoxifen inhibits growth of oestrogen receptor-negative A549 cells. | 1994 | Biochem. Pharmacol. | pmid:8304964 |
| Erman A et al. | Phospholipase A2 inhibitors. Differential inhibition of fatty acid acylation into kidney lipids by mepacrine and p-bromophenacyl bromide. | 1983 | Biochem. Pharmacol. | pmid:6870935 |
| Ondrias K et al. | Spin label study of the perturbation effect of the local anaesthetics tetracaine and dibucaine on synaptosomes at pharmacological concentrations. | 1987 | Biochem. Pharmacol. | pmid:2825709 |
| Risé P et al. | Differential modulation by simvastatin of the metabolic pathways in the n-9, n-6 and n-3 fatty acid series, in human monocytic and hepatocytic cell lines. | 2005 | Biochem. Pharmacol. | pmid:15763545 |
| Hara A et al. | Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs. | 2017 | Biochem. Pharmacol. | pmid:28450226 |
| Rendu F et al. | Ajoene, the antiplatelet compound derived from garlic, specifically inhibits platelet release reaction by affecting the plasma membrane internal microviscosity. | 1989 | Biochem. Pharmacol. | pmid:2539823 |
| Kerr BD et al. | Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. | 2009 | Biochem. Pharmacol. | pmid:19523458 |
| Bruce JS et al. | Desaturation and esterification of palmitic and stearic acids in cultured hepatocytes. | 1995 | Biochem. Soc. Trans. | pmid:7672331 |
| Sherrington EJ et al. | Lack of effect of different dietary saturated fatty acids on adipose tissue deposition in the rat. | 1996 | Biochem. Soc. Trans. | pmid:8736816 |
| Kaushik N and Vir S | Variations in fatty acid composition of neem seeds collected from the Rajasthan state of India. | 2000 | Biochem. Soc. Trans. | pmid:11171243 |
| Parveez GK et al. | Transgenic oil palm: production and projection. | 2000 | Biochem. Soc. Trans. | pmid:11171275 |
| Clouet P et al. | Mitochondrial respiration on rumenic and linoleic acids. | 2001 | Biochem. Soc. Trans. | pmid:11356175 |
| Liu Q et al. | Genetic modification of cotton seed oil using inverted-repeat gene-silencing techniques. | 2000 | Biochem. Soc. Trans. | pmid:11288706 |
| Negash S et al. | Phosphorylation of phospholamban by cAMP-dependent protein kinase enhances interactions between Ca-ATPase polypeptide chains in cardiac sarcoplasmic reticulum membranes. | 1996 | Biochemistry | pmid:8784178 |
| Richieri GV et al. | Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. | 2000 | Biochemistry | pmid:10852718 |
| Chen SC et al. | Calorimetric evidence for phase transitions in spin-label lipid bilayers. | 1982 | Biochemistry | pmid:7138849 |
| Zornetzer GA et al. | Solution structures of spinach acyl carrier protein with decanoate and stearate. | 2006 | Biochemistry | pmid:16618110 |