stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ferrari F et al. | The surface roughness of lactose particles can be modulated by wet-smoothing using a high-shear mixer. | 2004 | AAPS PharmSciTech | pmid:15760057 |
| Missaghi S and Fassihi R | A novel approach in the assessment of polymeric film formation and film adhesion on different pharmaceutical solid substrates. | 2004 | AAPS PharmSciTech | pmid:15760087 |
| Watanabe L et al. | Structural insights for fatty acid binding in a Lys49-phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid. | 2005 | Biochimie | pmid:15760708 |
| Schreiner T et al. | Immediate drug release from solid oral dosage forms. | 2005 | J Pharm Sci | pmid:15761936 |
| Risé P et al. | Differential modulation by simvastatin of the metabolic pathways in the n-9, n-6 and n-3 fatty acid series, in human monocytic and hepatocytic cell lines. | 2005 | Biochem. Pharmacol. | pmid:15763545 |
| Coscione AR and Artz WE | Vegetable oil stability at elevated temperatures in the presence of ferric stearate and ferrous octanoate. | 2005 | J. Agric. Food Chem. | pmid:15769140 |
| Garg M et al. | Hepatic de novo lipogenesis in stable low-birth-weight infants during exclusive breast milk feedings and during parenteral nutrition. | JPEN J Parenter Enteral Nutr | pmid:15772384 | |
| Aoshima H et al. | Glycerin fatty acid esters as a new lubricant of tablets. | 2005 | Int J Pharm | pmid:15778041 |
| Fujii M et al. | Preparation, characterization, and tableting of a solid dispersion of indomethacin with crospovidone. | 2005 | Int J Pharm | pmid:15778052 |
| Egerton TA et al. | Characterization of TiO2 nanoparticles surface modified with aluminum stearate. | 2005 | Langmuir | pmid:15780001 |
| Geslin JM et al. | [Allergic respiratory disorders and vein sclerosis with lauromacrogol 400]. | Therapie | pmid:15789831 | |
| Liu FX et al. | [Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--saponification reaction and saponification value]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:15806965 |
| Savickas A and Bernatoniene J | Optimization of "Askoeziuofito" tablets. | 2005 | Medicina (Kaunas) | pmid:15827390 |
| Fabianowski W et al. | Integrated circuits protection with the Langmuir-Blodgett Films. | 2005 | Bioelectrochemistry | pmid:15833702 |
| Shim SK et al. | Analysis of cellular fatty acids in Orientia tsutsugamushi as taxonomic markers. | 2005 | Microbiol. Immunol. | pmid:15840959 |
| Menéndez R et al. | In vitro and in vivo study of octacosanol metabolism. | 2005 Mar-Apr | Arch. Med. Res. | pmid:15847942 |
| Li W and Worosila GD | Quantitation of active pharmaceutical ingredients and excipients in powder blends using designed multivariate calibration models by near-infrared spectroscopy. | 2005 | Int J Pharm | pmid:15848006 |
| Adams M and Kwon GS | Spectroscopic investigation of the aggregation state of amphotericin B during loading, freeze-drying, and reconstitution of polymeric micelles. | 2004 | J Pharm Pharm Sci | pmid:15850542 |
| Scaglia N and Igal RA | Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cells. | 2005 | J. Biol. Chem. | pmid:15851470 |
| Ibáñez L et al. | Population-based drug-induced agranulocytosis. | 2005 | Arch. Intern. Med. | pmid:15851637 |
| Katsuta Y et al. | Unsaturated fatty acids induce calcium influx into keratinocytes and cause abnormal differentiation of epidermis. | 2005 | J. Invest. Dermatol. | pmid:15854043 |
| Tomassetti M et al. | Thermal analysis study of the interactions between acetaminophen and excipients in solid dosage forms and in some binary mixtures. | 2005 | J Pharm Biomed Anal | pmid:15862672 |
| Salzman RA et al. | Transcriptional profiling of sorghum induced by methyl jasmonate, salicylic acid, and aminocyclopropane carboxylic acid reveals cooperative regulation and novel gene responses. | 2005 | Plant Physiol. | pmid:15863699 |
| Hosaka S et al. | Effect of compression on interaction between 1,4-dihydropyridine compounds and lactose monohydrate. | 2005 | Chem. Pharm. Bull. | pmid:15863920 |
| Harris RK et al. | Quantification of bambuterol hydrochloride in a formulated product using solid-state NMR. | 2005 | J Pharm Biomed Anal | pmid:15869858 |
| Vanholder T et al. | Effect of non-esterified fatty acids on bovine granulosa cell steroidogenesis and proliferation in vitro. | 2005 | Anim. Reprod. Sci. | pmid:15885439 |
| Yagi T et al. | Lymphatic absorption of structured triacylglycerols, 1(3)-stearoyl-2,3 (1)-dilinoleoylglycerol and 2-linoleoyl-1,3-distearoylglycerol in rats. | 2004 | J. Nutr. Sci. Vitaminol. | pmid:15895523 |
| Jurkiewicz K | Adsorptive bubble separation of zinc and cadmium cations in presence of ferric and aluminum hydroxides. | 2005 | J Colloid Interface Sci | pmid:15897071 |
| Choi MY et al. | Pheromone biosynthetic pathways in the moths Heliothis subflexa and Heliothis virescens. | 2005 | Arch. Insect Biochem. Physiol. | pmid:15898118 |
| Green RL et al. | Comparison of near-infrared and laser-induced breakdown spectroscopy for determination of magnesium stearate in pharmaceutical powders and solid dosage forms. | 2005 | Appl Spectrosc | pmid:15901316 |
| Donoso M and Ghaly ES | Prediction of tablets disintegration times using near-infrared diffuse reflectance spectroscopy as a nondestructive method. | 2005 | Pharm Dev Technol | pmid:15926669 |
| Mirmehrabi M and Rohani S | An approach to solvent screening for crystallization of polymorphic pharmaceuticals and fine chemicals. | 2005 | J Pharm Sci | pmid:15929066 |
| Patil S and Chan C | Palmitic and stearic fatty acids induce Alzheimer-like hyperphosphorylation of tau in primary rat cortical neurons. | 2005 | Neurosci. Lett. | pmid:15939536 |
| Grabowski A et al. | Characterization of long-chain fatty-acid-degrading syntrophic associations from a biodegraded oil reservoir. | 2005 | Res. Microbiol. | pmid:15939576 |
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| Mitra A et al. | Inhibition of human term placental and fetal liver glutathione-S-transferases by fatty acids and fatty acid esters. | 1992 | Toxicol. Lett. | pmid:1595087 |
| Berry SE and Sanders TA | Influence of triacylglycerol structure of stearic acid-rich fats on postprandial lipaemia. | 2005 | Proc Nutr Soc | pmid:15960865 |
| Barkai G et al. | Community prescribing and resistant Streptococcus pneumoniae. | 2005 | Emerging Infect. Dis. | pmid:15963276 |
| Verma RK and Garg S | Selection of excipients for extended release formulations of glipizide through drug-excipient compatibility testing. | 2005 | J Pharm Biomed Anal | pmid:15967291 |
| Lin WC et al. | Determination of carotenoids in spear shrimp shells (Parapenaeopsis hardwickii) by liquid chromatography. | 2005 | J. Agric. Food Chem. | pmid:15969489 |
| Fernández-Moya V et al. | Oils from improved high stearic acid sunflower seeds. | 2005 | J. Agric. Food Chem. | pmid:15969513 |
| Vanholder T et al. | Effect of non-esterified fatty acids on bovine theca cell steroidogenesis and proliferation in vitro. | 2006 | Anim. Reprod. Sci. | pmid:15978752 |
| Shibata Y et al. | Evaluation of the compaction properties of a solid dispersion of indomethacin with crospovidone by tableting process analyzer. | 2005 | Chem. Pharm. Bull. | pmid:15997130 |
| Sahin N et al. | Lipase-catalyzed acidolysis of tripalmitin with hazelnut oil fatty acids and stearic acid to produce human milk fat substitutes. | 2005 | J. Agric. Food Chem. | pmid:15998148 |
| Jiang RG et al. | [Effect of surface modification on surface energy of lactose and performance of dry powder inhalations]. | 2005 | Yao Xue Xue Bao | pmid:16011271 |
| Zhao XY et al. | [Studies on chemical constituents from rhizome of Impatiens pritzellii var. hupehensis]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16011279 |
| Tappia PS et al. | Phospholipid profile of developing heart of rats exposed to low-protein diet in pregnancy. | 2005 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:16020521 |
| Morais S et al. | Dietary protein:lipid ratio and lipid nature affects fatty acid absorption and metabolism in a teleost larva. | 2005 | Br. J. Nutr. | pmid:16022750 |
| Serrano-Vega MJ et al. | Lipid characterization of seed oils from high-palmitic, low-palmitoleic, and very high-stearic acid sunflower lines. | 2005 | Lipids | pmid:16028719 |
| Mungur R et al. | Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene. | 2005 | J. Biomed. Biotechnol. | pmid:16046826 |