stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Infertility D007246 3 associated lipids
Obesity, Abdominal D056128 3 associated lipids
Yaws D015001 4 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Chancroid D002602 4 associated lipids
Foreign Bodies D005547 5 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Bronchitis D001991 6 associated lipids
Whooping Cough D014917 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
Gonorrhea D006069 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Liver Neoplasms D008113 8 associated lipids
Leprosy D007918 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Lymphadenitis D008199 8 associated lipids
Urethritis D014526 9 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Amnesia D000647 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Otitis Media D010033 12 associated lipids
Rosacea D012393 13 associated lipids
Urticaria D014581 13 associated lipids
Tremor D014202 15 associated lipids
Olfaction Disorders D000857 17 associated lipids
Lymphoma D008223 18 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Ischemia D007511 18 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Walash MI et al. Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids. 2011 Chem Cent J pmid:21996025
Prajapati ST et al. Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. 2011 ISRN Pharm pmid:22389845
Das SC et al. Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate. 2011 Eur J Pharm Sci pmid:21621612
Chaturvedi K et al. Floating matrix dosage form for propranolol hydrochloride based on gas formation technique: development and in vitro evaluation. 2010 Oct-Dec Sci Pharm pmid:21179326
Terekhova EA et al. [Stearic acid methyl ether: a new extracellular metabolite of the obligate methylotrophic bacterium Methylophilus quaylei]. 2010 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:20391761
Kristó K et al. Effect of lubricant on spreading of coating liquid on surface of tablets containing pancreatin. 2010 Jul-Aug Pharm Dev Technol pmid:19772392
Badawy SI et al. Effect of spray-dried mannitol on the performance of microcrystalline cellulose-based wet granulated tablet formulation. 2010 Jul-Aug Pharm Dev Technol pmid:20088677
Kaur G et al. Chitosan-carboxymethyl tamarind kernel powder interpolymer complexation: investigations for colon drug delivery. 2010 Jan-Mar Sci Pharm pmid:21179370
Stanisz B et al. Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. 2010 Jan-Feb Acta Pol Pharm pmid:20210086
Aburahma MH et al. Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid. 2010 Apr-Jun Sci Pharm pmid:21179352
Singh B et al. Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride. 2010 Apr-Jun Sci Pharm pmid:21179349
Chen Y et al. A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. 2010 Appl Spectrosc pmid:20925991
Mukherjee S et al. Stearic acid delivery to corneum from a mild and moisturizing cleanser. 2010 J Cosmet Dermatol pmid:20883293
Rawat MK et al. Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. 2010 Ther Deliv pmid:22816120
Patra S et al. In vitro evaluation of domperidone mouth dissolving tablets. 2010 Indian J Pharm Sci pmid:21969764
Akpa MM et al. Inhibition of insulin and T3-induced fatty acid synthase by hexanoate. 2010 Lipids pmid:20811782
Lin YK et al. Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery. 2010 Int J Nanomedicine pmid:20309398
Seerapu S and Srinivasan BP Development and Validation of RP-HPLC Method for the Estimation of Ivabradine Hydrochloride in Tablets. 2010 Indian J Pharm Sci pmid:21695008
Pedersen PJ et al. Liposomal formulation of retinoids designed for enzyme triggered release. 2010 J. Med. Chem. pmid:20405849
Liew CV et al. In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. 2010 Int J Pharm pmid:19922776
Harvey KA et al. Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. 2010 Clin Nutr pmid:19926177
Ohwoavworhua FO and Adelakun TA Non-wood Fibre Production of Microcrystalline Cellulose from Sorghum caudatum: Characterisation and Tableting Properties. 2010 Indian J Pharm Sci pmid:21188036
Contreras GA et al. Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. 2010 J. Dairy Sci. pmid:20494158
Karande AD et al. In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. 2010 Int J Pharm pmid:20558264
Kim IS and Oh IJ Preparation and characterization of stearic acid-pullulan nanoparticles. 2010 Arch. Pharm. Res. pmid:20512475
Wang J et al. Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. 2010 J Pharm Sci pmid:20533436
Karande AD et al. Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend. 2010 Int J Pharm pmid:20472048
Akihisa T et al. Triterpene alcohol and fatty acid composition of shea nuts from seven African countries. 2010 J Oleo Sci pmid:20513968
Shishu VR et al. Development of taste masked oral formulation of ornidazole. 2010 Indian J Pharm Sci pmid:20838525
Gohel MC et al. Fabrication and Evaluation of Bi-layer Tablet Containing Conventional Paracetamol and Modified Release Diclofenac Sodium. 2010 Indian J Pharm Sci pmid:20838522
Phaechamud T et al. Preparation of Coated Valproic Acid and Sodium Valproate Sustained-release Matrix Tablets. 2010 Indian J Pharm Sci pmid:20838520
Huthmacher C et al. Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. 2010 BMC Syst Biol pmid:20807400
Noguchi Y et al. Ketogenic essential amino acids modulate lipid synthetic pathways and prevent hepatic steatosis in mice. 2010 PLoS ONE pmid:20706589
Maher AC et al. Women have higher protein content of beta-oxidation enzymes in skeletal muscle than men. 2010 PLoS ONE pmid:20700461
Wang Q et al. One-Step Synthesis of Monodisperse In-Doped ZnO Nanocrystals. 2010 Nanoscale Res Lett pmid:20672040
Blanco M and Peguero A Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. 2010 J Pharm Biomed Anal pmid:20044229
Swanson EJ et al. Phospholipid-stabilized microbubble foam for injectable oxygen delivery. 2010 Langmuir pmid:20873807
Yasuda A et al. Self-organizing map analysis using multivariate data from theophylline powders predicted by a thin-plate spline interpolation. 2010 J Pharm Sci pmid:20845452
Shaikh SA et al. Formulation and evaluation of s-(-)-amlodipine besylate and nebivolol hydrochloride tablets. 2010 J Adv Pharm Technol Res pmid:22247846
Tiwari G et al. Cyclodextrins in delivery systems: Applications. 2010 J Pharm Bioallied Sci pmid:21814436
Shidhaye SS et al. Buccal drug delivery of pravastatin sodium. 2010 AAPS PharmSciTech pmid:20300898
van den Berg SA et al. High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity. 2010 Nutr Metab (Lond) pmid:20346174
Xing Z et al. The fabrication of novel nanobubble ultrasound contrast agent for potential tumor imaging. 2010 Nanotechnology pmid:20220227
Li Y et al. Preparation and characterization of coverage-controlled CaCO3 nanoparticles. 2010 J Colloid Interface Sci pmid:20202642
Romanowicz L and Bańkowski E Sphingolipids of human umbilical cord vein and their alteration in preeclampsia. 2010 Mol. Cell. Biochem. pmid:20155487
Abdel-Mottaleb MM et al. In vitro drug release mechanism from lipid nanocapsules (LNC). 2010 Int J Pharm pmid:20149853
Taneri F et al. In vitro and in vivo evaluation of oral tablet formulations prepared with ketoconazole and hydroxypropyl-beta-cyclodextrin. 2010 Drug Deliv pmid:20148713
Wang J et al. Lubrication in tablet formulations. 2010 Eur J Pharm Biopharm pmid:20096779
Yeop Han C et al. Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. 2010 Diabetes pmid:19934003
Raeside JI and Christie HL Diaryl dimers of estradiol and of estrone may be formed as major metabolites by mouse mammary glands. 2010 Biochem. Biophys. Res. Commun. pmid:20875396