stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Decalcification, Pathologic D003649 1 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Anemia, Dyserythropoietic, Congenital D000742 2 associated lipids
Obesity, Abdominal D056128 3 associated lipids
Syphilis, Congenital D013590 3 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Pneumoconiosis D011009 3 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Calculi D002137 3 associated lipids
Relapsing Fever D012061 3 associated lipids
Tenosynovitis D013717 3 associated lipids
Infertility D007246 3 associated lipids
Yaws D015001 4 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Syphilis, Latent D013592 4 associated lipids
Prostatic Diseases D011469 4 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Chancroid D002602 4 associated lipids
Foreign Bodies D005547 5 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Bronchitis D001991 6 associated lipids
Whooping Cough D014917 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
Gonorrhea D006069 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Lymphadenitis D008199 8 associated lipids
Liver Neoplasms D008113 8 associated lipids
Leprosy D007918 8 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Urethritis D014526 9 associated lipids
Brain Diseases, Metabolic, Inborn D020739 10 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Amnesia D000647 12 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Otitis Media D010033 12 associated lipids
Rosacea D012393 13 associated lipids
Urticaria D014581 13 associated lipids
Tremor D014202 15 associated lipids
Olfaction Disorders D000857 17 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Lymphoma D008223 18 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Ischemia D007511 18 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Erectile Dysfunction D007172 19 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Staiger K et al. Insulin and its analogue glargine do not affect viability and proliferation of human coronary artery endothelial and smooth muscle cells. 2005 Diabetologia pmid:16078017
Dennis M and Kolattukudy PE A cobalt-porphyrin enzyme converts a fatty aldehyde to a hydrocarbon and CO. 1992 Proc. Natl. Acad. Sci. U.S.A. pmid:1608940
el-Naghy MA et al. Fungistatic action of natural oils and fatty acids on dermatophytic and saprophytic fungi. 1992 Zentralbl. Mikrobiol. pmid:1609554
Armoni M et al. Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements. 2005 J. Biol. Chem. pmid:16096283
Wang X et al. Solid state characteristics of ternary solid dispersions composed of PVP VA64, Myrj 52 and itraconazole. 2005 Int J Pharm pmid:16105723
Li D et al. Plasma coagulation factor VII activity and its correlates in healthy men. 2005 Eur J Clin Nutr pmid:16106263
St-Onge L et al. Rapid quantitative analysis of magnesium stearate in tablets using laser-induced breakdown spectroscopy. 2005 J Pharm Pharm Sci pmid:16124938
Guo LJ et al. [The structure and properties of self-assembly complex LB films of silver nanoparticles]. 2005 Guang Pu Xue Yu Guang Pu Fen Xi pmid:16128074
Hoppu U et al. Breast milk fatty acid composition is associated with development of atopic dermatitis in the infant. 2005 J. Pediatr. Gastroenterol. Nutr. pmid:16131990
Staiger H et al. Fatty acid-induced differential regulation of the genes encoding peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in human skeletal muscle cells that have been differentiated in vitro. 2005 Diabetologia pmid:16132959
Parra-Barraza H et al. Chitosan-cholesterol and chitosan-stearic acid interactions at the air-water interface. 2005 Sep-Oct Biomacromolecules pmid:16153076
Gelders GG et al. Potato phosphorylase catalyzed synthesis of amylose-lipid complexes. 2005 Sep-Oct Biomacromolecules pmid:16153100
Hong J et al. The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: studies in vitro. 2005 Metab. Clin. Exp. pmid:16154432
Thijssen MA and Mensink RP Small differences in the effects of stearic acid, oleic acid, and linoleic acid on the serum lipoprotein profile of humans. 2005 Am. J. Clin. Nutr. pmid:16155261
Chen Y et al. Side reactions in controlling the quality, yield, and stability of high quality colloidal nanocrystals. 2005 J. Am. Chem. Soc. pmid:16173766
Turkoglu M et al. Evaluation of hexagonal boron nitride as a new tablet lubricant. 2005 Pharm Dev Technol pmid:16176018
Rao KP et al. Impact of solid-state properties on lubrication efficacy of magnesium stearate. 2005 Pharm Dev Technol pmid:16176023
Leroy JL et al. Non-esterified fatty acids in follicular fluid of dairy cows and their effect on developmental capacity of bovine oocytes in vitro. 2005 Reproduction pmid:16183866
Dentin R et al. Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation. 2005 J. Clin. Invest. pmid:16184193
Stanisz B The influence of pharmaceutical excipients on quinapril hydrochloride stability. 2005 May-Jun Acta Pol Pharm pmid:16193811
Kiuru PS and Wähälä K Microwave-assisted synthesis of deuterium labeled estrogen fatty acid esters. 2006 Steroids pmid:16198386
Vueba ML et al. Role of cellulose ether polymers on ibuprofen release from matrix tablets. 2005 Drug Dev Ind Pharm pmid:16207613
Jonat S et al. Influence of compacted hydrophobic and hydrophilic colloidal silicon dioxide on tableting properties of pharmaceutical excipients. 2005 Drug Dev Ind Pharm pmid:16207616
Zeman M et al. N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination. 2006 J. Nutr. Biochem. pmid:16214329
Terán M et al. Hydrophilic and lipophilic radiopharmaceuticals as tracers in pharmaceutical development: in vitro--in vivo studies. 2005 BMC Nucl Med pmid:16232323
Nohynek GJ et al. Repeated topical treatment, in contrast to single oral doses, with Vitamin A-containing preparations does not affect plasma concentrations of retinol, retinyl esters or retinoic acids in female subjects of child-bearing age. 2006 Toxicol. Lett. pmid:16243460
Lee J Intrinsic adhesion properties of poly(vinyl pyrrolidone) to pharmaceutical materials: humidity effect. 2005 Macromol Biosci pmid:16245267
Bajaj M et al. Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients. 2005 Diabetes pmid:16249438
Choi HJ et al. Structure and thermal behavior of a layered silver hydroxyalkanecarboxylate. 2003 J Colloid Interface Sci pmid:16256665
Lad MD et al. Protein-lipid interactions at the air/water interface. 2005 Phys Chem Chem Phys pmid:16273149
Chiang EP et al. Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. 2005 Arthritis Res. Ther. pmid:16277693
Segre N et al. Surface characterization of recycled tire rubber to be used in cement paste matrix. 2002 J Colloid Interface Sci pmid:16290558
Garcia Marquez MA et al. [The effect of two lubricants (magnesium stearate and pruv) in the formation of tablets of four anti-ulcer agents/ by means of direct compression]. 1992 Pharm Acta Helv pmid:1631172
Jahn T and Steffens KJ Press chamber coating as external lubrication for high speed rotary presses: lubricant spray rate optimization. 2005 Drug Dev Ind Pharm pmid:16316850
Thijssen MA et al. Stearic, oleic, and linoleic acids have comparable effects on markers of thrombotic tendency in healthy human subjects. 2005 J. Nutr. pmid:16317124
Mayer KM et al. Linking enzyme sequence to function using Conserved Property Difference Locator to identify and annotate positions likely to control specific functionality. 2005 BMC Bioinformatics pmid:16318626
Garton NJ and Sutcliffe IC Identification of a lipoarabinomannan-like lipoglycan in the actinomycete Gordonia bronchialis. 2006 Arch. Microbiol. pmid:16320036
Fukami J et al. Development of fast disintegrating compressed tablets using amino acid as disintegration accelerator: evaluation of wetting and disintegration of tablet on the basis of surface free energy. 2005 Chem. Pharm. Bull. pmid:16327184
Bonanome A et al. Metabolic effects of dietary stearic acid in mice: changes in the fatty acid composition of triglycerides and phospholipids in various tissues. 1992 Atherosclerosis pmid:1632865
Wang L et al. [Synthesis, characterization and evaluation of octadecyl ester-bonded monolithic column]. 2005 Se Pu pmid:16350795
Tatavarti AS et al. Assessment of NIR spectroscopy for nondestructive analysis of physical and chemical attributes of sulfamethazine bolus dosage forms. 2005 AAPS PharmSciTech pmid:16353969
Soares LA et al. Dry granulation and compression of spray-dried plant extracts. 2005 AAPS PharmSciTech pmid:16353993
Navaneethan CV et al. Application of powder rheometer to determine powder flow properties and lubrication efficiency of pharmaceutical particulate systems. 2005 AAPS PharmSciTech pmid:16353997
Pérez-Vich B et al. Molecular analysis of the high stearic acid content in sunflower mutant CAS-14. 2006 Theor. Appl. Genet. pmid:16362273
Wurster DE et al. The influence of magnesium stearate on the Hiestand Tableting Indices and other related mechanical properties of maltodextrins. 2005 Pharm Dev Technol pmid:16370175
Wyttenbach N et al. Drug-excipient compatibility testing using a high-throughput approach and statistical design. 2005 Pharm Dev Technol pmid:16370179
Pirozhkov SV et al. Effect of chronic consumption of ethanol and vitamin E on fatty acid composition and lipid peroxidation in rat heart tissue. 1992 Jul-Aug Alcohol pmid:1637499
Demirbas A et al. Adsorption thermodynamics of stearic acid onto bentonite. 2006 J. Hazard. Mater. pmid:16386845
Ding EL et al. Chocolate and prevention of cardiovascular disease: a systematic review. 2006 Nutr Metab (Lond) pmid:16390538
Douliez JP et al. Self-assembly of fatty acid-alkylboladiamine salts. 2006 Langmuir pmid:16401110