stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yalcin H et al. | Effect of gamma-irradiation on some chemical characteristics and volatile content of linseed. | 2011 | J Med Food | pmid:21548804 |
| Islam A and Ehsan A | Comparison of suture material and technique of closure of subcutaneous fat and skin in caesarean section. | 2011 | N Am J Med Sci | pmid:22540072 |
| Waters LJ et al. | Controlled microwave processing applied to the pharmaceutical formulation of ibuprofen. | 2011 | AAPS PharmSciTech | pmid:21842309 |
| Chaturvedi K et al. | Floating matrix dosage form for propranolol hydrochloride based on gas formation technique: development and in vitro evaluation. | 2010 Oct-Dec | Sci Pharm | pmid:21179326 |
| Terekhova EA et al. | [Stearic acid methyl ether: a new extracellular metabolite of the obligate methylotrophic bacterium Methylophilus quaylei]. | 2010 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:20391761 |
| Kristó K et al. | Effect of lubricant on spreading of coating liquid on surface of tablets containing pancreatin. | 2010 Jul-Aug | Pharm Dev Technol | pmid:19772392 |
| Badawy SI et al. | Effect of spray-dried mannitol on the performance of microcrystalline cellulose-based wet granulated tablet formulation. | 2010 Jul-Aug | Pharm Dev Technol | pmid:20088677 |
| Kaur G et al. | Chitosan-carboxymethyl tamarind kernel powder interpolymer complexation: investigations for colon drug delivery. | 2010 Jan-Mar | Sci Pharm | pmid:21179370 |
| Stanisz B et al. | Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. | 2010 Jan-Feb | Acta Pol Pharm | pmid:20210086 |
| Aburahma MH et al. | Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid. | 2010 Apr-Jun | Sci Pharm | pmid:21179352 |
| Singh B et al. | Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride. | 2010 Apr-Jun | Sci Pharm | pmid:21179349 |
| Westerbacka J et al. | Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. | 2010 | Gastroenterology | pmid:20600015 |
| Even P et al. | Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. | 2010 | Metab. Clin. Exp. | pmid:19775712 |
| Hirabara SM et al. | Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells. | 2010 | J. Cell. Physiol. | pmid:19780047 |
| Lehto T et al. | Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. | 2010 | J Control Release | pmid:19744531 |
| Almeida CP et al. | Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. | 2010 | Int J Nanomedicine | pmid:20957219 |
| Ram HN et al. | Formulation and evaluation of floating tablets of liquorice extract. | 2010 | Pharmacognosy Res | pmid:21589757 |
| Elbaz A et al. | Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro. | 2010 | J. Cell. Mol. Med. | pmid:19382912 |
| Jain S et al. | Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. | 2010 | J Young Pharm | pmid:21264091 |
| Naumova EA et al. | Influence of individual saliva secretion on fluoride bioavailability. | 2010 | Open Dent J | pmid:21221176 |
| Patel BP et al. | Formulation and evaluation of mouth dissolving tablets of cinnarizine. | 2010 | Indian J Pharm Sci | pmid:21218071 |
| Kotagale NR et al. | Carbopol 934-Sodium Alginate-Gelatin Mucoadhesive Ondansetron Tablets for Buccal Delivery: Effect of pH Modifiers. | 2010 | Indian J Pharm Sci | pmid:21218058 |
| Swami G et al. | Soyabean powder as a novel diluent in tablet formulation of simvastatin. | 2010 | Indian J Pharm Sci | pmid:21218051 |
| Balch RJ and Trescot A | Extended-release morphine sulfate in treatment of severe acute and chronic pain. | 2010 | J Pain Res | pmid:21197323 |
| Zhou QT et al. | Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach. | 2010 | Int J Pharm | pmid:20435112 |
| Cohn JS et al. | Reduction in intestinal cholesterol absorption by various food components: mechanisms and implications. | 2010 | Atheroscler Suppl | pmid:20439167 |
| Pantusa M and Bartucci R | Kinetics of stearic acid transfer between human serum albumin and sterically stabilized liposomes. | 2010 | Eur. Biophys. J. | pmid:20306030 |
| Mir VG et al. | Application of crustacean chitin as a co-diluent in direct compression of tablets. | 2010 | AAPS PharmSciTech | pmid:20238188 |
| Remya K et al. | Formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets. | 2010 | J Young Pharm | pmid:21042477 |
| Sateesha S et al. | Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. | 2010 | J Young Pharm | pmid:21042476 |
| Hurko O et al. | Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. | 2010 | Int J Alzheimers Dis | pmid:20981353 |
| Pan PH et al. | Stearic acid attenuates cholestasis-induced liver injury. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20036638 |
| Zhou YY et al. | Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin. | 2010 | Int J Pharm | pmid:20420886 |
| Wu T et al. | Study on superhydrophobic hybrids fabricated from multiwalled carbon nanotubes and stearic acid. | 2010 | J Colloid Interface Sci | pmid:20427047 |
| Rivera CA et al. | Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis. | 2010 | BMC Gastroenterol | pmid:20509914 |
| Barupal DK et al. | Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. | 2010 | BMC Biotechnol. | pmid:20492649 |
| Lin SY et al. | Solid-state transformation of different gabapentin polymorphs upon milling and co-milling. | 2010 | Int J Pharm | pmid:20561572 |
| Asai T and Fujimoto Y | Cyclic fatty acyl glycosides in the glandular trichome exudate of Silene gallica. | 2010 | Phytochemistry | pmid:20541780 |
| Foster SP and Johnson CP | Feeding and hemolymph trehalose concentration influence sex pheromone production in virgin Heliothis virescens moths. | 2010 | J. Insect Physiol. | pmid:20540946 |
| Thörn K and Bergsten P | Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate. | 2010 | J. Cell. Biochem. | pmid:20524206 |
| Zhou QT et al. | Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders. | 2010 | Eur J Pharm Sci | pmid:20433919 |
| Nokhodchi A et al. | Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives. | 2010 | Daru | pmid:22615598 |
| Croxton RS et al. | Variation in amino acid and lipid composition of latent fingerprints. | 2010 | Forensic Sci. Int. | pmid:20413233 |
| Milanovic J et al. | Microencapsulation of flavors in carnauba wax. | 2010 | Sensors (Basel) | pmid:22315575 |
| Nagaich U et al. | Design and evaluation of a metronidazole central core matrix tablet. | 2010 | J Adv Pharm Technol Res | pmid:22247836 |
| Bhattacharya S and Nagaich U | Assessment of anti-nociceptive efficacy of costus speciosus rhizome in swiss albino mice. | 2010 | J Adv Pharm Technol Res | pmid:22247830 |
| Tripathi B et al. | Fortification of sorghum (Sorghum vulgare) and pearl millet (Pennisetum glaucum) flour with zinc. | 2010 | J Trace Elem Med Biol | pmid:20685098 |
| Kuo WT et al. | Polymeric micelles comprising stearic acid-grafted polyethyleneimine as nonviral gene carriers. | 2010 | J Nanosci Nanotechnol | pmid:21133072 |
| Li YW et al. | [Studies on the chemical constituents of Ficus microcarpa]. | 2010 | Zhong Yao Cai | pmid:21049616 |
| Thomas CP et al. | Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. | 2010 | J. Biol. Chem. | pmid:20061396 |