stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Capková P et al. | Structure of montmorillonite cointercalated with stearic acid and octadecylamine: modeling, diffraction, IR spectroscopy. | 2006 | J Colloid Interface Sci | pmid:16631185 |
| Hu FQ et al. | A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. | 2006 | Int J Pharm | pmid:16632285 |
| Csallany AS et al. | Effect of high stearic acid containing fat on markers for in vivo lipid peroxidation. | 2005 | Int J Food Sci Nutr | pmid:16638661 |
| Shibata Y et al. | Fluidity and tableting characteristics of a powder solid dispersion of the low melting drugs ketoprofen and ibuprofen with crospovidone. | 2006 | Drug Dev Ind Pharm | pmid:16638683 |
| Uematsu Y et al. | Determination of magnesium stearate in capsule- or tablet-type supplements. | 2006 Mar-Apr | J AOAC Int | pmid:16640294 |
| Azevedo-Martins AK et al. | Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. | 2006 | Toxicol In Vitro | pmid:16644178 |
| Givan CV and Stumpf PK | Fat Metabolism in Higher Plants: XLV. Some Factors Regulating Fatty Acid Synthesis by Isolated Spinach Chloroplasts. | 1971 | Plant Physiol. | pmid:16657651 |
| Kannangara CG and Stumpf PK | Fat Metabolism in Higher Plants: XLVII. The Effect of Nitrite and Other Anions on the Formation of Unsaturated Fatty Acids by Isolated Chloroplasts. | 1972 | Plant Physiol. | pmid:16657990 |
| Donaldson RP and Beevers H | Lipid composition of organelles from germinating castor bean endosperm. | 1977 | Plant Physiol. | pmid:16659829 |
| Pollard MR and Stumpf PK | Biosynthesis of C(20) and C(22) Fatty Acids by Developing Seeds of Limnanthes alba: CHAIN ELONGATION AND Delta5 DESATURATION. | 1980 | Plant Physiol. | pmid:16661496 |
| Ashworth EN and Christiansen MN | Effect of Temperature and BASF 13 338 on the Lipid Composition and Respiration of Wheat Roots. | 1981 | Plant Physiol. | pmid:16661741 |
| Lem NW and Stumpf PK | In Vitro Fatty Acid Synthesis and Complex Lipid Metabolism in the Cyanobacterium, Anabaena Variabilis: II. Acyl Transfer and Complex Lipid Formation. | 1984 | Plant Physiol. | pmid:16663690 |
| Roughan PG | Phosphatidylglycerol and chilling sensitivity in plants. | 1985 | Plant Physiol. | pmid:16664127 |
| Sparace SA et al. | A preliminary analysis of Fatty Acid synthesis in pea roots. | 1988 | Plant Physiol. | pmid:16666088 |
| Waterhouse KE et al. | Within and between breed differences in freezing tolerance and plasma membrane fatty acid composition of boar sperm. | 2006 | Reproduction | pmid:16672353 |
| Urai M et al. | Structural analysis of an extracellular polysaccharide produced by Rhodococcus rhodochrous strain S-2. | 2006 | Carbohydr. Res. | pmid:16676419 |
| Tönges L et al. | Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons. | 2006 | RNA | pmid:16699166 |
| Petelska AD et al. | Interfacial tension of the lipid membrane formed from lipid-fatty acid and lipid-amine systems. | 2007 | Bioelectrochemistry | pmid:16713376 |
| Desrosiers Lachiver E et al. | Insights into the role of electrostatic forces on the behavior of dry pharmaceutical particulate systems. | 2006 | Pharm. Res. | pmid:16715390 |
| Otsuka M and Yamane I | Prediction of tablet hardness based on near infrared spectra of raw mixed powders by chemometrics. | 2006 | J Pharm Sci | pmid:16721793 |
| Zou T et al. | Support vector regression for determination of component of compound oxytetracycline powder on near-infrared spectroscopy. | 2006 | Anal. Biochem. | pmid:16723110 |
| Wood R | Sterospecific analysis of hepatoma, host liver, and normal rat liver triglycerides from animals on chow and fat free diets. | 1975 | Lipids | pmid:167260 |
| Uehara Y et al. | Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element. | 2007 | Atherosclerosis | pmid:16730733 |
| Raith K et al. | Towards a molecular characterization of pharmaceutical excipients: mass spectrometric studies of ethoxylated surfactants. | 2006 | Int J Pharm | pmid:16730931 |
| Planinsek O et al. | Surface analysis of powder binary mixtures with ATR FTIR spectroscopy. | 2006 | Int J Pharm | pmid:16730933 |
| Söderhäll I et al. | Characterization of a hemocyte intracellular fatty acid-binding protein from crayfish (Pacifastacus leniusculus) and shrimp (Penaeus monodon). | 2006 | FEBS J. | pmid:16734719 |
| Chen G | An exfoliated polyamide-6/layered double hydroxide nanocomposite via in situ intercalative polymerization between positively charged inorganic platelets. | 2006 | J Nanosci Nanotechnol | pmid:16736781 |
| Titov VN et al. | [Fibrate-induced changes in the serum lipid contents of individual C16 and C18 fatty acids in patients with hyperlipidemia]. | 2006 | Klin. Lab. Diagn. | pmid:16756155 |
| Hu FQ et al. | Shell cross-linked stearic acid grafted chitosan oligosaccharide self-aggregated micelles for controlled release of paclitaxel. | 2006 | Colloids Surf B Biointerfaces | pmid:16759840 |
| Dancey CP et al. | Nucleotide supplementation: a randomised double-blind placebo controlled trial of IntestAidIB in people with Irritable Bowel Syndrome [ISRCTN67764449]. | 2006 | Nutr J | pmid:16762076 |
| MacDonald AM and Lucy CA | Highly efficient protein separations in capillary electrophoresis using a supported bilayer/diblock copolymer coating. | 2006 | J Chromatogr A | pmid:16777117 |
| Iot T et al. | Synthesis of a new phosphatidylserine spin-label and calcium-induced lateral phase separation in phosphatidylserine-phosphatidylcholine membranes. | 1975 | Biochemistry | pmid:167814 |
| Song MJ et al. | Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16781673 |
| Seitavuopio P et al. | Monitoring tablet surface roughness during the film coating process. | 2006 | AAPS PharmSciTech | pmid:16796349 |
| Lachiver ED et al. | Agglomeration tendency in dry pharmaceutical granular systems. | 2006 | Eur J Pharm Biopharm | pmid:16797949 |
| Kapuśniak J and Tomasik P | Lipid microencapsulation in starch. | 2006 | J Microencapsul | pmid:16801245 |
| Martinello T et al. | Optimization of poorly compactable drug tablets manufactured by direct compression using the mixture experimental design. | 2006 | Int J Pharm | pmid:16806756 |
| Xu B and Yan B | Photophysical properties of novel lanthanide (Tb3+, Dy3+, Eu3+) complexes with long chain para-carboxyphenol ester p-L-benzoate (L=dodecanoyloxy, myristoyloxy, palmitoyloxy and stearoyloxy). | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16815090 |
| Pillai KG et al. | Spontaneous tooth exfoliation, maxillary osteomyelitis and facial scarring following trigeminal herpes zoster infection. | 2006 | Prim Dent Care | pmid:16836817 |
| Shankar BV and Patnaik A | J-aggregates in matrix stabilized two-dimensional azobenzene derivatives. | 2006 | J Colloid Interface Sci | pmid:16844137 |
| Zhu S et al. | Acid soap and phase behavior of stearic acid and triethanolamine stearate. | 2005 | J Phys Chem B | pmid:16852443 |
| Anand M et al. | Synthesis and steric stabilization of silver nanoparticles in neat carbon dioxide solvent using fluorine-free compounds. | 2006 | J Phys Chem B | pmid:16869575 |
| Bunker MJ et al. | A nanoscale study of particle friction in a pharmaceutical system. | 2006 | Int J Pharm | pmid:16875789 |
| Ishioka T et al. | Infrared study on annealing effect on conformation of zinc stearate. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16875870 |
| Hsieh HJ et al. | Production of ascorbyl palmitate by surfactant-coated lipase in organic media. | 2006 | J. Agric. Food Chem. | pmid:16881677 |
| Song GY et al. | High-fat feeding reduces endothelium-dependent vasodilation in rats: differential mechanisms for saturated and unsaturated fatty acids? | 2006 | Clin. Exp. Pharmacol. Physiol. | pmid:16895544 |
| El Hagrasy AS et al. | Evaluation of risk and benefit in the implementation of near-infrared spectroscopy for monitoring of lubricant mixing. | 2006 | Pharm Dev Technol | pmid:16895841 |
| Duan Y et al. | Effect of molecular sieves on lipase-catalyzed esterification of rutin with stearic acid. | 2006 | J. Agric. Food Chem. | pmid:16910711 |
| Johansson TP and Leach GW | Sum frequency generation study of Langmuir Blodgett film architecture. | 2006 | J Phys Chem B | pmid:16913791 |
| Gibon Y et al. | Integration of metabolite with transcript and enzyme activity profiling during diurnal cycles in Arabidopsis rosettes. | 2006 | Genome Biol. | pmid:16916443 |