stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Varshosaz J et al. | Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. | 2010 | Int J Prev Med | pmid:21566772 |
| Aly S | Detachment and recovery index: A new parameter measuring powder compressibility. | 2010 | J Adv Pharm Technol Res | pmid:22247881 |
| Pires de Souza FC et al. | In vitro comparison of the radiopacity of cavity lining materials with human dental structures. | 2010 | J Conserv Dent | pmid:20859477 |
| Yang X et al. | In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. | 2010 | Drug Dev Ind Pharm | pmid:20141448 |
| Chitapanarux I et al. | Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. | 2010 | Radiat Oncol | pmid:20444243 |
| Xing Z et al. | Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. | 2010 | Acta Biomater | pmid:20226284 |
| Salbu L et al. | Direct compression behavior of low- and high-methoxylated pectins. | 2010 | AAPS PharmSciTech | pmid:20013080 |
| Su C et al. | A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:20732836 |
| Yoo HJ and HÃ¥kansson K | Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. | 2010 | Anal. Chem. | pmid:20704384 |
| Valencia-Chamorro SA et al. | Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. | 2010 | J. Food Sci. | pmid:21535515 |
| Alshamsan A et al. | Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. | 2009 Jan-Feb | Mol. Pharm. | pmid:19053537 |
| Liu K et al. | Isolation and biochemical characterization of two lipases from a metagenomic library of China Holstein cow rumen. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19486892 |
| Robinson DM et al. | Influence of interesterification of a stearic acid-rich spreadable fat on acute metabolic risk factors. | 2009 | Lipids | pmid:18982377 |
| Liu Q et al. | Synthesis of hollow Co structures with netlike framework. | 2009 | Langmuir | pmid:19368338 |
| Roberts LD et al. | Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse. | 2009 | Genome Med | pmid:19968882 |
| Rajesh KS et al. | Effect of hydrophilic natural gums in formulation of oral-controlled release matrix tablets of propranolol hydrochloride. | 2009 | Pak J Pharm Sci | pmid:19339235 |
| Hu FQ et al. | Enhanced cellular uptake of chlorine e6 mediated by stearic acid-grafted chitosan oligosaccharide micelles. | 2009 | J Drug Target | pmid:19343607 |
| Pouget EM et al. | The initial stages of template-controlled CaCO3 formation revealed by cryo-TEM. | 2009 | Science | pmid:19286549 |
| Oosterveer MH et al. | High fat feeding induces hepatic fatty acid elongation in mice. | 2009 | PLoS ONE | pmid:19557132 |
| Yadav VR et al. | Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease. | 2009 | J. Pharm. Pharmacol. | pmid:19222903 |
| Luppi B et al. | Gastroresistant microcapsules: new approaches for site-specific delivery of ketoprofen. | 2009 | Drug Deliv | pmid:19555305 |
| Chakraborty S et al. | Development of extended release divalproex sodium tablets containing hypdrophobic and hydrophilic matrix. | 2009 | Curr Drug Deliv | pmid:19604143 |
| Otsuka M and Yamane I | Prediction of tablet properties based on near infrared spectra of raw mixed powders by chemometrics: Scale-up factor of blending and tableting processes. | 2009 | J Pharm Sci | pmid:19530073 |
| Pudney PD et al. | Characterising the phase behaviour of stearic acid and its triethanolamine soap and acid-soap by infrared spectroscopy. | 2009 | Phys Chem Chem Phys | pmid:19562130 |
| Nonomura Y et al. | Phase behavior of bile acid/lipid/water systems containing model dietary lipids. | 2009 | J Colloid Interface Sci | pmid:19682701 |
| Huang J et al. | Quality by design case study: an integrated multivariate approach to drug product and process development. | 2009 | Int J Pharm | pmid:19664698 |
| Cao C et al. | [Chemical study on petroleum ether portion of Sarcandra hainanensis]. | 2009 | Zhongguo Zhong Yao Za Zhi | pmid:19639789 |
| Hu FQ et al. | Synthesis and antitumor activity of doxorubicin conjugated stearic acid-g-chitosan oligosaccharide polymeric micelles. | 2009 | Biomaterials | pmid:19782395 |
| Clemente TE and Cahoon EB | Soybean oil: genetic approaches for modification of functionality and total content. | 2009 | Plant Physiol. | pmid:19783644 |
| Herczeg M et al. | Toward synthesis of the isosteric sulfonate analogues of the AT-III binding domain of heparin. | 2009 | Org. Lett. | pmid:19473011 |
| Mattes RD | Oral thresholds and suprathreshold intensity ratings for free fatty acids on 3 tongue sites in humans: implications for transduction mechanisms. | 2009 | Chem. Senses | pmid:19357229 |
| Shen J et al. | Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery. | 2009 | J Control Release | pmid:19393270 |
| Wang YY et al. | [Studies on the chemical constituents of Sarcopyramis nepalensis]. | 2009 | Zhong Yao Cai | pmid:20034215 |
| Swamy PV et al. | Preparation and evaluation of orodispersible tablets of pheniramine maleate by effervescent method. | 2009 | Indian J Pharm Sci | pmid:20336216 |
| Hanlon PR et al. | Aqueous extracts from dietary supplements influence the production of inflammatory cytokines in immortalized and primary T lymphocytes. | 2009 | BMC Complement Altern Med | pmid:20003431 |
| Teraoka R et al. | Effect of pharmaceutical excipients on the stability of trichlormethiazide tablets under humid conditions. | 2009 | Chem. Pharm. Bull. | pmid:19952441 |
| Hoppa MB et al. | Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules. | 2009 | Cell Metab. | pmid:19945403 |
| Weber K et al. | Lesions in the Larynx of Wistar RccHan: WIST Rats. | 2009 | J Toxicol Pathol | pmid:22271998 |
| Lee HB et al. | Production of calcium-stearate by lipase using hydrogenated beef tallow. | 2009 | Appl. Biochem. Biotechnol. | pmid:18506631 |
| Kobayashi K et al. | Photocatalytic decomposition of organic thin films in a nanometer-scale by an atomic force microscope. | 2009 | J Nanosci Nanotechnol | pmid:19504857 |
| Yonezawa T et al. | Saturated fatty acids stimulate and insulin suppresses CIDE-A expression in bovine mammary epithelial cells. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19427838 |
| Kessler W et al. | Using scattering and absorption spectra as MCR-hard model constraints for diffuse reflectance measurements of tablets. | 2009 | Anal. Chim. Acta | pmid:19427467 |
| Hesta M et al. | The effect of vitamin C supplementation in healthy dogs on antioxidative capacity and immune parameters. | 2009 | J Anim Physiol Anim Nutr (Berl) | pmid:19386005 |
| Thumma S and Repka MA | Compatibility studies of promethazine hydrochloride with tablet excipients by means of thermal and non-thermal methods. | 2009 | Pharmazie | pmid:19348341 |
| Deb C et al. | A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen. | 2009 | PLoS ONE | pmid:19562030 |
| Ahn S et al. | Biochemical characterization of the lipid-binding properties of a broccoli cuticular wax-associated protein, WAX9D, and its application. | 2009 | BMB Rep | pmid:19558796 |
| van Die MD et al. | Are we drawing the right conclusions from randomised placebo-controlled trials? A post-hoc analysis of data from a randomised controlled trial. | 2009 | BMC Med Res Methodol | pmid:19549306 |
| Peter A et al. | Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo. | 2009 | Diabetes | pmid:19478146 |
| Ussher JR et al. | Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. | 2009 | Diabetes | pmid:19478144 |
| Barakat NS et al. | Controlled-release carbamazepine matrix granules and tablets comprising lipophilic and hydrophilic components. | 2009 | Drug Deliv | pmid:19555310 |