stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Ropero J et al. | Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation. | 2011 | Appl Spectrosc | pmid:21396195 |
Mohamed IO | Lipase-catalyzed acidolysis of palm mid fraction oil with palmitic and stearic Fatty Acid mixture for production of cocoa butter equivalent. | 2013 | Appl. Biochem. Biotechnol. | pmid:23877586 |
Yassin AA et al. | Effect of enzymatic interesterification on melting point of palm olein. | 2003 | Appl. Biochem. Biotechnol. | pmid:12909731 |
Lee HB et al. | Production of calcium-stearate by lipase using hydrogenated beef tallow. | 2009 | Appl. Biochem. Biotechnol. | pmid:18506631 |
el-Sharkawy SH et al. | Microbiological transformations of lipids: acyl-specific hydrolysis of lard by yeasts. | 1993 | Appl. Environ. Microbiol. | pmid:8480999 |
Huang FC et al. | Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. | 2014 | Appl. Environ. Microbiol. | pmid:24242247 |
Paczkowski S and Schütz S | Post-mortem volatiles of vertebrate tissue. | 2011 | Appl. Microbiol. Biotechnol. | pmid:21720824 |
Ashby RD et al. | Methyl-branched poly(hydroxyalkanoate) biosynthesis from 13-methyltetradecanoic acid and mixed isostearic acid isomer substrates. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19644690 |
Sakuradani E et al. | Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19415268 |
Liu RS and Tang YJ | Quantitative analysis for the effect of plant oil and fatty acid on Tuber melanosporum culture by uniform design combined with partial least squares regression. | 2010 | Appl. Microbiol. Biotechnol. | pmid:20473608 |