stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Lurie E et al. | N-(2-hydroxybenzyl)-omega-amino carbonic acids and their derivatives as tools for biochemical and biophysical investigations. | 1993 | Biochem. Mol. Biol. Int. | pmid:8358340 |
Zock PL et al. | Effects of stearic acid and trans fatty acids versus linoleic acid on blood pressure in normotensive women and men. | 1993 | Eur J Clin Nutr | pmid:8365385 |
Cisar LA et al. | Interleukin-1 selectively potentiates bradykinin-stimulated arachidonic acid release from human synovial fibroblasts. | 1993 | Cell. Signal. | pmid:8373725 |
Raines DE and Miller KW | The role of charge in lipid selectivity for the nicotinic acetylcholine receptor. | 1993 | Biophys. J. | pmid:8386010 |
Vilim A et al. | A simple thin-layer chromatographic identification procedure for erythromycin base, stearate, estolate and ethylsuccinate. | 1977 | J. Chromatogr. | pmid:838805 |
Viswanathan R et al. | Strained-layer van der Waals epitaxy in a Langmuir-Blodgett film. | 1993 | Science | pmid:8392751 |
Emken EA et al. | Influence of linoleic acid on desaturation and uptake of deuterium-labeled palmitic and stearic acids in humans. | 1993 | Biochim. Biophys. Acta | pmid:8399342 |
Imaizumi K et al. | Fat containing stearic acid increases fecal neutral steroid excretion and catabolism of low density lipoproteins without affecting plasma cholesterol concentration in hamsters fed a cholesterol-containing diet. | 1993 | J. Nutr. | pmid:8410360 |
Wada H et al. | In vitro ferredoxin-dependent desaturation of fatty acids in cyanobacterial thylakoid membranes. | 1993 | J. Bacteriol. | pmid:8419301 |
Baer HH and Wu X | Synthesis of alpha,alpha-trehalose 2,3- and 2,3'-diesters with palmitic and stearic acid: potential immunoreactants for the serodiagnosis of tuberculosis. | 1993 | Carbohydr. Res. | pmid:8431934 |