stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Liu Q et al. | Genetic modification of cotton seed oil using inverted-repeat gene-silencing techniques. | 2000 | Biochem. Soc. Trans. | pmid:11288706 |
Fukui E et al. | Effect of magnesium stearate or calcium stearate as additives on dissolution profiles of diltiazem hydrochloride from press-coated tablets with hydroxypropylmethylcellulose acetate succinate in the outer shell. | 2001 | Int J Pharm | pmid:11274815 |
Harwood JL and James AT | Metabolism of trans-3-hexadecenoic acid in broad bean. | 1975 | Eur. J. Biochem. | pmid:1126340 |
Alves MM et al. | Effects of lipids and oleic acid on biomass development in anaerobic fixed-bed reactors. Part II: Oleic acid toxicity and biodegradability. | 2001 | Water Res. | pmid:11257881 |
Hatta I et al. | X-ray diffraction study on ordered, disordered and reconstituted intercellular lipid lamellar structure in stratum corneum. | 2001 | Biophys. Chem. | pmid:11254216 |
Nishioka Y and Yoshino H | Lymphatic targeting with nanoparticulate system. | 2001 | Adv. Drug Deliv. Rev. | pmid:11251245 |
Sabir A et al. | Formulation and process optimization to eliminate picking from market image tablets. | 2001 | Int J Pharm | pmid:11250098 |
Höltje M et al. | Molecular dynamics simulations of stratum corneum lipid models: fatty acids and cholesterol. | 2001 | Biochim. Biophys. Acta | pmid:11248214 |
Thosar SS et al. | A comparison of reflectance and transmittance near-infrared spectroscopic techniques in determining drug content in intact tablets. | 2001 | Pharm Dev Technol | pmid:11247272 |
Liang P et al. | [Chemical constituents of Pericampylus glaucus (Lam.) Merr]. | 1998 | Zhongguo Zhong Yao Za Zhi | pmid:11243154 |