stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Willie BM et al. | Possible explanation for the white band artifact seen in clinically retrieved polyethylene tibial components. | 2000 | J. Biomed. Mater. Res. | pmid:11007625 |
Broderick PA et al. | Monoamine neurotransmitters in resected hippocampal subparcellations from neocortical and mesial temporal lobe epilepsy patients: in situ microvoltammetric studies. | 2000 | Brain Res. | pmid:10996135 |
Hattori Y et al. | Role of phospholipase A2 in cholesterol gallstone formation is associated with biliary phospholipid species selection at the site of hepatic excretion: indirect evidence. | 2000 | Dig. Dis. Sci. | pmid:10961723 |
Hatipoglu ON and Tasan Y | A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. | 2000 | Yonsei Med. J. | pmid:10957888 |
Hennig B et al. | Fatty acid-mediated activation of vascular endothelial cells. | 2000 | Metab. Clin. Exp. | pmid:10954018 |
MuzÃk M and MuzÃková J | [Effect of magnesium stearate on internal failure of Avicel PH 101 tablets]. | 2000 | Ceska Slov Farm | pmid:10953461 |
Ishioka T et al. | Infrared and XAFS study on structure and transition behavior of zinc stearate. | 2000 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:10952134 |
Kim YC et al. | Differential regulation of the stearoyl-CoA desaturase genes by thiazolidinediones in 3T3-L1 adipocytes. | 2000 | J. Lipid Res. | pmid:10946019 |
Khalil MH et al. | Topical application of docosanol- or stearic acid-containing creams reduces severity of phenol burn wounds in mice. | 2000 | Contact Derm. | pmid:10945745 |
Wardrop J et al. | Determination of erythromycin and related substances in enteric-coated tablet formulations by reversed-phase liquid chromatography. | 2000 | J Pharm Sci | pmid:10944374 |