stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Green B et al. | Qualitative and quantitative changes in milk fat during lactation in the tammar wallaby (Macropus eugenii). | 1983 | Aust. J. Biol. Sci. | pmid:6675645 |
Tulenko TN and Rabinowitz JL | Metabolism of C14 mevalonate by adult and fetal arteries. | 1983 | Artery | pmid:6677248 |
Foudin L et al. | Ethanol consumption and serum lipid profiles in Sinclair(S-1) miniature swine. | 1984 | Life Sci. | pmid:6700380 |
Sakaguchi M et al. | Effect of dietary unsaturated and saturated fats on azoxymethane-induced colon carcinogenesis in rats. | 1984 | Cancer Res. | pmid:6704963 |
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Hanna GM | Nuclear magnetic resonance spectroscopic determination of dicyclomine hydrochloride in tablet, capsule, and injection dosage forms. | 1984 Mar-Apr | J Assoc Off Anal Chem | pmid:6725188 |
Pediconi MF and RodrÃguez de Turco EB | Free fatty acid content and release kinetics as manifestations of cerebral lateralization in mouse brain. | 1984 | J. Neurochem. | pmid:6726237 |
Kemp P et al. | The hydrogenation of some cis- and trans-octadecenoic acids to stearic acid by a rumen Fusocillus sp. | 1984 | Br. J. Nutr. | pmid:6743636 |
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Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |
Broekman MJ et al. | Fatty acid composition of phosphatidylinositol and phosphatidic acid in stimulated platelets. Persistence of arachidonyl-stearyl structure. | 1981 | J. Biol. Chem. | pmid:6790536 |
Bonini de Romanelli IC et al. | Phosphatidic acid, phosphatidylinositol, phosphatidylserine and cardiolipin in the course of early embryonic development. Fatty acid composition and content in whole toad embryos and in mitochondrial fractions. | 1981 | Biochim. Biophys. Acta | pmid:6791698 |
Yamauchi T et al. | Thermal adaptation of Tetrahymena membranes with special reference to mitochondria. Role of cardiolipin in fluidity of mitochondrial membranes. | 1981 | Biochim. Biophys. Acta | pmid:6797472 |
Moore KH et al. | beta-Hydroxy fatty acid production by ischemic rabbit heart. | 1982 | J. Clin. Invest. | pmid:6799549 |
Walsh C et al. | Arachidonate metabolism by neutrophils. | 1981 | Prog. Lipid Res. | pmid:6804984 |
Hong SL and Deykin D | Activation of phospholipases A2 and C in pig aortic endothelial cells synthesizing prostacyclin. | 1982 | J. Biol. Chem. | pmid:6806265 |
McGimpsey JG et al. | Comparison of serum erythromycin concentration following administration of 100 mg erythromycin ethyl succinate intramuscularly and 500 mg erythromycin stearate orally. | 1981 | Int J Oral Surg | pmid:6807878 |
Goto M et al. | Evidence for a correlation between swimming velocity and membrane fluidity of Tetrahymena cells. | 1982 | Biochim. Biophys. Acta | pmid:6818990 |
Oriel JD et al. | Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. | 1982 Oct-Dec | Sex Transm Dis | pmid:6821502 |
Pethick DW et al. | The metabolism of circulating non-esterified fatty acids by the whole animal, hind-limb muscle and uterus of pregnant ewes. | 1983 | Br. J. Nutr. | pmid:6821682 |
Edwards EK and Edwards EK | Allergic reaction to triethanolamine stearate in a sunscreen. | 1983 | Cutis | pmid:6831931 |
Chapkin RS et al. | Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis. | 1983 | J. Lab. Clin. Med. | pmid:6833842 |
Hillmar I et al. | Influence of fatty acids on microsomal diacylglycerol acyltransferase activity in primary cultures of hepatocytes. | 1983 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:6840704 |
Warrell DA et al. | Pathophysiology and immunology of the Jarisch-Herxheimer-like reaction in louse-borne relapsing fever: comparison of tetracycline and slow-release penicillin. | 1983 | J. Infect. Dis. | pmid:6842024 |
Zeisel SH et al. | Formation of methylamines from ingested choline and lecithin. | 1983 | J. Pharmacol. Exp. Ther. | pmid:6842395 |
Foot M et al. | Some properties, including the substrate in vivo, of the delta 9-desaturase in Micrococcus cryophilus. | 1983 | Biochem. J. | pmid:6847622 |
Quinn PA et al. | Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. | 1983 | Am. J. Obstet. Gynecol. | pmid:6849358 |
Streichman S et al. | Unique profile for erythrocyte membrane acetylcholinesterase in hereditary spherocytosis. | 1983 | Biochim. Biophys. Acta | pmid:6849970 |
Sobel JD et al. | Legionella bozemanii. Still another cause of pneumonia. | 1983 | JAMA | pmid:6854903 |
Stults BM et al. | Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease. | 1983 | South. Med. J. | pmid:6857302 |
Slomiany A et al. | Isolation of fatty acids covalently bound to the gastric mucus glycoprotein of normal and cystic fibrosis patients. | 1983 | Biochem. Biophys. Res. Commun. | pmid:6860340 |
Slomiany A et al. | Covalently linked fatty acids in gastric mucus glycoprotein of cystic fibrosis patients. | 1983 | J. Biol. Chem. | pmid:6863300 |
Khan KA et al. | The effect of mixing time of magnesium stearate on the tableting properties of dried microcrystalline cellulose. | 1983 | Pharm Acta Helv | pmid:6867042 |
Erman A et al. | Phospholipase A2 inhibitors. Differential inhibition of fatty acid acylation into kidney lipids by mepacrine and p-bromophenacyl bromide. | 1983 | Biochem. Pharmacol. | pmid:6870935 |
Flood MT et al. | Vitamin A utilization in human retinal pigment epithelial cells in vitro. | 1983 | Invest. Ophthalmol. Vis. Sci. | pmid:6885309 |
Chien JL and Hogan EL | Novel pentahexosyl ganglioside of the globo series purified from chicken muscle. | 1983 | J. Biol. Chem. | pmid:6885798 |
Gorrissen H et al. | Deuterium magnetic resonance of selectively deuterated cholesteryl esters in dipalmitoyl phosphatidylcholine dispersions. | 1981 | Biochim. Biophys. Acta | pmid:6894863 |
Tinsley IJ et al. | Tissue fatty acid changes and tumor incidence in C3H mice ingesting cottonseed oil. | 1982 | Lipids | pmid:6896358 |
Larsson K and Glantz PO | Microbial adhesion to surfaces with different surface charges. | 1981 | Acta Odontol. Scand. | pmid:6948486 |
Wei TC | Quantitative determination of chemical composition of gallstones by infrared absorption spectrophotometry. | 1982 | Taiwan Yi Xue Hui Za Zhi | pmid:6954245 |
Slomiany BL et al. | Lipid composition of the matrix of human submandibular salivary gland stones. | 1982 | Arch. Oral Biol. | pmid:6958224 |
Selenke WM et al. | Nonantibiotic effects of macrolide antibiotics of the oleandomycin-erythromycin group with special reference to their "steroid-sparing" effects. | 1980 | J. Allergy Clin. Immunol. | pmid:6966289 |
Stein Y et al. | Intralysosomal hydrolysis of cholesterol esters of varying fatty acid composition in cultured human skin fibroblasts. | 1978 | Biochim. Biophys. Acta | pmid:698242 |
della Ventura A and della Ventura D | [Clinical experiments with erythromycin stearate in surgery of the oral cavity]. | 1982 May-Jun | Odontostomatol Implantoprotesi | pmid:6984149 |
Sanders KL et al. | Relapse of Legionnaires' disease in a renal transplant recipient. | 1980 | Arch. Intern. Med. | pmid:6992727 |
Fraser DG | Selection of an oral erythromycin product. | 1980 | Am J Hosp Pharm | pmid:6998290 |
Schuler LA et al. | Effect of luteinizing hormone of the lipid composition of rat ovaries. | 1978 | J. Endocrinol. | pmid:702016 |
Nagai J et al. | Increased proportion of medium chain fatty acids in nystatin-resistant yeast mutants. | 1981 | Lipids | pmid:7022083 |
RÃ¥dberg T et al. | Metabolic studies in gestational diabetic women during contraceptive treatment: effects on glucose tolerance and fatty acid composition of serum lipids. | 1982 | Gynecol. Obstet. Invest. | pmid:7035304 |
Maddux MS et al. | The effect of erythromycin on theophylline pharmacokinetics at steady state. | 1982 | Chest | pmid:7042226 |