stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fretts AM et al. | Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length. | 2016 | J. Nutr. | pmid:26701797 |
| Sergeant S et al. | Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. | 2016 | Br. J. Nutr. | pmid:26615716 |
| Monteyne T et al. | Stearic acid and high molecular weight PEO as matrix for the highly water soluble metoprolol tartrate in continuous twin-screw melt granulation. | 2016 | Int J Pharm | pmid:27452420 |
| Ariyasu A et al. | Delay effect of magnesium stearate on tablet dissolution in acidic medium. | 2016 | Int J Pharm | pmid:27444551 |
| Schulze C et al. | A one-stage cultivation process for lipid- and carbohydrate-rich biomass of Scenedesmus obtusiusculus based on artificial and natural water sources. | 2016 | Bioresour. Technol. | pmid:27394996 |
| MužÃková J and KubÃÄková A | A study of compressibility and compactibility of directly compressible tableting materials containing tramadol hydrochloride. | 2016 | Acta Pharm | pmid:27383891 |
| Adler C et al. | Molecularly designed lipid microdomains for solid dispersions using a polymer/inorganic carrier matrix produced by hot-melt extrusion. | 2016 | Int J Pharm | pmid:26721729 |
| Wood MH et al. | Comparative Adsorption of Saturated and Unsaturated Fatty Acids at the Iron Oxide/Oil Interface. | 2016 | Langmuir | pmid:26707597 |
| Bothun GD et al. | Cooperative effects of fatty acids and n-butanol on lipid membrane phase behavior. | 2016 | Colloids Surf B Biointerfaces | pmid:26700234 |
| Uvanesh K et al. | Effect of Span 60 on the Microstructure, Crystallization Kinetics, and Mechanical Properties of Stearic Acid Oleogels: An In-Depth Analysis. | 2016 | J. Food Sci. | pmid:26677007 |