stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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BozdaÄŸ-Pehlivan S et al. | Evaluation of drug-excipient interaction in the formulation of celecoxib tablets. | 2011 May-Jun | Acta Pol Pharm | pmid:21648198 |
Malik K et al. | Taste masked microspheres of ofloxacin: formulation and evaluation of orodispersible tablets. | 2011 Jul-Sep | Sci Pharm | pmid:21886910 |
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Uchimoto T et al. | A comparative study of glycerin fatty acid ester and magnesium stearate on the dissolution of acetaminophen tablets using the analysis of available surface area. | 2011 | Eur J Pharm Biopharm | pmid:21284955 |
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Park MY et al. | Hog millet (Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice. | 2011 | Nutr Res Pract | pmid:22259675 |
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Meissner M et al. | Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate. | 2011 | PLoS ONE | pmid:22087215 |
Guschina I et al. | Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. | 2011 | Lipids | pmid:20963507 |
Protière M et al. | Rational design of the gram-scale synthesis of nearly monodisperse semiconductor nanocrystals. | 2011 | Nanoscale Res Lett | pmid:21791060 |
Rajendraprasad N et al. | Titrimetric and spectrophotometric assay of oxcarbazepine in pharmaceuticals using N-bromosuccinimide and bromopyrogallol red. | 2011 | Int J Anal Chem | pmid:21785594 |
Bhope SG et al. | Design and development of a stable polyherbal formulation based on the results of compatibility studies. | 2011 | Pharmacognosy Res | pmid:21772756 |
Williams KJ et al. | The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. | 2011 | Tuberculosis (Edinb) | pmid:21764638 |
Lacaze C et al. | The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. | 2011 | Malar. J. | pmid:21605361 |
Houmard JA et al. | Is there a metabolic program in the skeletal muscle of obese individuals? | 2011 | J Obes | pmid:21603262 |
Li C et al. | Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate. | 2011 | Carcinogenesis | pmid:21586513 |
Mahdi ES et al. | Effect of surfactant and surfactant blends on pseudoternary phase diagram behavior of newly synthesized palm kernel oil esters. | 2011 | Drug Des Devel Ther | pmid:21792294 |
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Liu H et al. | A surfactant-free recipe for shape-controlled synthesis of CdSe nanocrystals. | 2011 | Nanotechnology | pmid:21169661 |
Pingali K et al. | Mixing order of glidant and lubricant--influence on powder and tablet properties. | 2011 | Int J Pharm | pmid:21356286 |
Zaki Rizkalla CM et al. | In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery. | 2011 | AAPS PharmSciTech | pmid:21800216 |
Roblegg E et al. | Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion. | 2011 | Eur J Pharm Biopharm | pmid:21801834 |
Van Hoeck V et al. | Elevated non-esterified fatty acid concentrations during bovine oocyte maturation compromise early embryo physiology. | 2011 | PLoS ONE | pmid:21858021 |
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Someshwar K et al. | Formulation and evaluation of effervescent floating tablets of tizanidine hydrochloride. | 2011 | Acta Pharm | pmid:21684848 |
Pani NR et al. | Compatibility studies of nateglinide with excipients in immediate release tablets. | 2011 | Acta Pharm | pmid:21684850 |
Němcová-Fürstová V et al. | Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction. | 2011 | Cell. Physiol. Biochem. | pmid:21691070 |
Xu M et al. | Novel functions of lipid-binding protein 5 in Caenorhabditis elegans fat metabolism. | 2011 | J. Biol. Chem. | pmid:21697096 |
White HM et al. | Differential regulation of bovine pyruvate carboxylase promoters by fatty acids and peroxisome proliferator-activated receptor-α agonist. | 2011 | J. Dairy Sci. | pmid:21700028 |