stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Hara A et al. | Human carbonyl reductase 1 participating in intestinal first-pass drug metabolism is inhibited by fatty acids and acyl-CoAs. | 2017 | Biochem. Pharmacol. | pmid:28450226 |
Prasinou P et al. | Fatty acid-based lipidomics and membrane remodeling induced by apoE3 and apoE4 in human neuroblastoma cells. | 2017 | Biochim Biophys Acta Biomembr | pmid:28688796 |
Oki E et al. | Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil. | 2017 | Br. J. Nutr. | pmid:28633686 |
Naing C and Whittaker MA | Anabolic steroids for treating pressure ulcers. | 2017 | Cochrane Database Syst Rev | pmid:28631809 |
Wang Y et al. | Docosahexaenoyl serotonin emerges as most potent inhibitor of IL-17 and CCL-20 released by blood mononuclear cells from a series of N-acyl serotonins identified in human intestinal tissue. | 2017 | Biochim. Biophys. Acta | pmid:28526351 |
Cosenza G et al. | A novel polymorphism in the oxytocin receptor encoding gene (OXTR) affects milk fatty acid composition in Italian Mediterranean river buffalo. | 2017 | J. Dairy Res. | pmid:28524009 |
Chitprasert P and Ngamekaue N | Stability Enhancement of Ocimum Sanctum Linn. Essential Oils Using Stearic Acid in Aluminum Carboxymethyl Cellulose Film-Coated Gelatin Microcapsules. | 2017 | J. Food Sci. | pmid:28494101 |
Mirabi P et al. | Does different BMI influence oocyte and embryo quality by inducing fatty acid in follicular fluid? | 2017 | Taiwan J Obstet Gynecol | pmid:28420500 |
Yang D et al. | Liposomes Incorporating Transferrin and Stearic Acid-modified Octa-arginine for siRNA Delivery. | 2017 | Anticancer Res. | pmid:28373438 |
Yang TS et al. | Functionalities of chitosan conjugated with stearic acid and gallic acid and application of the modified chitosan in stabilizing labile aroma compounds in an oil-in-water emulsion. | 2017 | Food Chem | pmid:28317761 |
Trementozzi AN et al. | Engineered particles demonstrate improved flow properties at elevated drug loadings for direct compression manufacturing. | 2017 | Int J Pharm | pmid:28284921 |
Sguizzato M et al. | Solid lipid nanoparticles for the delivery of 1,3,5-triaza-7-phosphaadamantane (PTA) platinum (II) carboxylates. | 2017 | Mater Sci Eng C Mater Biol Appl | pmid:28254304 |
Bayard M et al. | Free fatty acids and their esters modulate isothermal crystallization of anhydrous milk fat. | 2017 | Food Chem | pmid:27719901 |
Wang XH et al. | High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2. | 2017 | Front Pharmacol | pmid:28555106 |
Han Y et al. | Natural variations in stearoyl-acp desaturase genes affect the conversion of stearic to oleic acid in maize kernel. | 2017 | Theor. Appl. Genet. | pmid:27717956 |
Hosaka S and Tokunaga Y | Differences in Powder Properties of Two 1,4-Dihydropyridine-Type Compounds Evaluated through Thermal Analysis. | 2017 | Chem. Pharm. Bull. | pmid:29199222 |
Narang AS et al. | Assessment of Tablet Surface Hardness by Laser Ablation and Its Correlation With the Erosion Tendency of Core Tablets. | 2017 | J Pharm Sci | pmid:27686683 |
Pantub K et al. | Preparation of Salicylic Acid Loaded Nanostructured Lipid Carriers Using Box-Behnken Design: Optimization, Characterization and Physicochemical Stability. | 2017 | J Oleo Sci | pmid:29199206 |
Qu L et al. | Single-step Coprocessing of Cohesive Powder via Mechanical Dry Coating for Direct Tablet Compression. | 2017 | J Pharm Sci | pmid:27665128 |
Wang W et al. | Synthesis, self-assembly, and in vitro toxicity of fatty acids-modified Bletilla striata polysaccharide. | 2017 | Artif Cells Nanomed Biotechnol | pmid:26754958 |