stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Crouzier D et al. | Pulsed electromagnetic field at 9.71 GHz increase free radical production in yeast (Saccharomyces cerevisiae). | 2009 | Pathol. Biol. | pmid:18321660 |
| Chen JJ et al. | seco-Abietane diterpenoids, a phenylethanoid derivative, and antitubercular constituents from Callicarpa pilosissima. | 2009 | J. Nat. Prod. | pmid:19193025 |
| Peters GH et al. | Effects of fatty acid inclusion in a DMPC bilayer membrane. | 2009 | J Phys Chem B | pmid:19195101 |
| Sugisawa K et al. | Rapid quantitative analysis of magnesium stearate in pharmaceutical powders and solid dosage forms by atomic absorption: method development and application in product manufacturing. | 2009 | J Pharm Biomed Anal | pmid:19195812 |
| Tuomasjukka SS et al. | Regio-distribution of stearic acid is not conserved in chylomicrons after ingestion of randomised, stearic acid-rich fat in a single meal. | 2009 | J. Nutr. Biochem. | pmid:19195862 |
| Parlati C et al. | Pulmonary spray dried powders of tobramycin containing sodium stearate to improve aerosolization efficiency. | 2009 | Pharm. Res. | pmid:19184617 |
| Matharu Z et al. | Langmuir-Blodgett film based on MEH-PPV for cholesterol biosensor. | 2009 | Anal. Chim. Acta | pmid:19185127 |
| Slobodkina GB et al. | Geoglobus acetivorans sp. nov., an iron(III)-reducing archaeon from a deep-sea hydrothermal vent. | 2009 | Int. J. Syst. Evol. Microbiol. | pmid:19628601 |
| Royter M et al. | Thermostable lipases from the extreme thermophilic anaerobic bacteria Thermoanaerobacter thermohydrosulfuricus SOL1 and Caldanaerobacter subterraneus subsp. tengcongensis. | 2009 | Extremophiles | pmid:19579003 |
| Asgary S et al. | Evaluation of fatty acid content of some Iranian fast foods with emphasis on trans fatty acids. | 2009 | Asia Pac J Clin Nutr | pmid:19713177 |
| Ashby RD et al. | Methyl-branched poly(hydroxyalkanoate) biosynthesis from 13-methyltetradecanoic acid and mixed isostearic acid isomer substrates. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19644690 |
| Hommelberg PP et al. | Fatty acid-induced NF-kappaB activation and insulin resistance in skeletal muscle are chain length dependent. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:18957619 |
| Hodson L et al. | Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:18940935 |
| Jacob S and Shirwaikar A | Preparation and evaluation of microencapsulated fast melt tablets of ambroxol hydrochloride. | 2009 | Indian J Pharm Sci | pmid:20490294 |
| Roni MA et al. | Formulation and in vitro Evaluation of Alfuzosin Extended Release Tablets Using Directly Compressible Eudragit. | 2009 | Indian J Pharm Sci | pmid:20490290 |
| Kerr BD et al. | Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. | 2009 | Biochem. Pharmacol. | pmid:19523458 |
| Rabkin SW et al. | Stearic acid-induced cardiac lipotoxicity is independent of cellular lipid and is mitigated by the fatty acids oleic and capric acid but not by the PPAR agonist troglitazone. | 2009 | Exp. Physiol. | pmid:19482900 |
| McLean S et al. | Effect of filtration on morphine and particle content of injections prepared from slow-release oral morphine tablets. | 2009 | Harm Reduct J | pmid:20025779 |
| Kratzer A et al. | Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia. | 2009 | J. Lipid Res. | pmid:18812595 |
| Artwohl M et al. | Fatty acids induce apoptosis in human smooth muscle cells depending on chain length, saturation, and duration of exposure. | 2009 | Atherosclerosis | pmid:18597758 |
| Laus G et al. | Ionic liquids as superior solvents for headspace gas chromatography of residual solvents with very low vapor pressure, relevant for pharmaceutical final dosage forms. | 2009 | J Chromatogr A | pmid:19560778 |
| Andersen CA et al. | Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Guérin. | 2009 | J. Immunol. | pmid:19620310 |
| Walter AA et al. | Acute effects of a thermogenic nutritional supplement on cycling time to exhaustion and muscular strength in college-aged men. | 2009 | J Int Soc Sports Nutr | pmid:19594929 |
| Bergman BC et al. | Intramuscular lipid metabolism in the insulin resistance of smoking. | 2009 | Diabetes | pmid:19581421 |
| Kinnings SL et al. | Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis. | 2009 | PLoS Comput. Biol. | pmid:19578428 |
| Ukrainczyk M et al. | Precipitation of different calcite crystal morphologies in the presence of sodium stearate. | 2009 | J Colloid Interface Sci | pmid:18848702 |
| Kotronen A et al. | Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver. | 2009 | Diabetes | pmid:18952834 |
| Qureshi J et al. | Chronomodulated drug delivery system of salbutamol sulphate for the treatment of nocturnal asthma. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046744 |
| Issa MM et al. | Novel atomic absorption spectrometric and rapid spectrophotometric methods for the quantitation of paracetamol in saliva: application to pharmacokinetic studies. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046743 |
| Gohel MC and Sarvaiya KG | Exploration of cold extrusion for the preparation of enteric minitablets of isoniazid. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046736 |
| Gohel MC et al. | Modulation of venlafaxine hydrochloride release from press coated matrix tablet. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046735 |
| Bhise SB and Aloorkar NH | Formulation and in vitro Evaluation of Floating Capsules of Theophylline. | 2008 Mar-Apr | Indian J Pharm Sci | pmid:20046717 |
| Setty CM et al. | Development of fast dispersible aceclofenac tablets: effect of functionality of superdisintegrants. | 2008 Mar-Apr | Indian J Pharm Sci | pmid:20046709 |
| Masareddy RS et al. | Development of mouth dissolving tablets of clozapine using two different techniques. | 2008 Jul-Aug | Indian J Pharm Sci | pmid:20046788 |
| Syed AA and Syeda A | Spectrophotometric determination of certain benzimidazole proton pump inhibitors. | 2008 Jul-Aug | Indian J Pharm Sci | pmid:20046782 |
| Baldania SL et al. | RP-HPLC Estimation of Risperidone in Tablet Dosage Forms. | 2008 Jul-Aug | Indian J Pharm Sci | pmid:20046778 |
| Ganesh S et al. | In vitro Evaluation of the Effect of Combination of Hydrophilic and Hydrophobic Polymers on Controlled Release Zidovudine Matrix Tablets. | 2008 Jul-Aug | Indian J Pharm Sci | pmid:20046771 |
| Cocchi M et al. | [Membrane platelet fatty acids: biochemical characterisation of the ischemic cardiovascular disease, characteristics of the paediatric age, through an artificial neural network interpretation]. | 2008 Jan-Feb | Pediatr Med Chir | pmid:18491675 |
| Varghese N et al. | Investigations of the growth kinetics of capped CdSe and CdS nanocrystals by a combined use of small angle X-ray scattering and other techniques. | 2008 | Chem Asian J | pmid:18637656 |
| Shah DA et al. | Stability Indicating RP-HPLC Estimation of Nebivolol Hydrochloride in Pharmaceutical Formulations. | 2008 | Indian J Pharm Sci | pmid:21394254 |
| Gonçalves-Araújo T et al. | Application of percolation theory in the study of an extended release Verapamil hydrochloride formulation. | 2008 | Int J Pharm | pmid:18621491 |
| Labonté ED et al. | Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18718999 |
| Late SG and Banga AK | Thermal and non-thermal methods to evaluate compatibility of granisetron hydrochloride with tablet excipients. | 2008 | Pharmazie | pmid:18604989 |
| Sachse F et al. | Anti-inflammatory effects of ciprofloxacin in S. aureus Newman induced nasal inflammation in vitro. | 2008 | J Inflamm (Lond) | pmid:18664275 |
| De Girolamo J et al. | Layer-by-layer assembled composite films of side-functionalized poly(3-hexylthiophene) and CdSe nanocrystals: electrochemical, spectroelectrochemical and photovoltaic properties. | 2008 | Phys Chem Chem Phys | pmid:18597017 |
| Reyna SM et al. | Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. | 2008 | Diabetes | pmid:18633101 |
| Ikonen M et al. | Controlled complexation of plasmid DNA with cationic polymers: effect of surfactant on the complexation and stability of the complexes. | 2008 | Colloids Surf B Biointerfaces | pmid:18583110 |
| Yee JK et al. | Compartmentalization of stearoyl-coenzyme A desaturase 1 activity in HepG2 cells. | 2008 | J. Lipid Res. | pmid:18599738 |
| Shah RB et al. | Stability indicating validated HPLC method for quantification of levothyroxine with eight degradation peaks in the presence of excipients. | 2008 | Int J Pharm | pmid:18524511 |
| Liang L and Fang Y | Photoluminescence of a mixed Langmuir-Blodgett film of C(60) and stearic acid at room temperature. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17499018 |
| Bermúdez L et al. | A candidate gene survey of quantitative trait loci affecting chemical composition in tomato fruit. | 2008 | J. Exp. Bot. | pmid:18552354 |
| Schwab U et al. | Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism--the GENOBIN study. | 2008 | PLoS ONE | pmid:18612464 |
| Ivanova T et al. | Action of Humicola lanuginosa lipase on mixed monomolecular films of tricaprylin and polyethylene glycol stearate. | 2008 | Colloids Surf B Biointerfaces | pmid:18178069 |
| UÄŸurlu T and TurkoÄŸlu M | Hexagonal boron nitride as a tablet lubricant and a comparison with conventional lubricants. | 2008 | Int J Pharm | pmid:18160235 |
| Gianotti A et al. | Involvement of cell fatty acid composition and lipid metabolism in adhesion mechanism of Listeria monocytogenes. | 2008 | Int. J. Food Microbiol. | pmid:18160165 |
| Galperin MY | Social bacteria and asocial eukaryotes. | 2008 | Environ. Microbiol. | pmid:18199122 |
| Harding L et al. | The development of microthermal analysis and photothermal microspectroscopy as novel approaches to drug-excipient compatibility studies. | 2008 | Int J Pharm | pmid:18162342 |
| Zhu CQ et al. | Facile Phosphine-Free Synthesis of CdSe/ZnS Core/Shell Nanocrystals Without Precursor Injection. | 2008 | Nanoscale Res Lett | pmid:21777485 |
| Desai D et al. | Solid-state interaction of stearic acid with povidone and its effect on dissolution stability of capsules. | 2008 | Int J Pharm | pmid:18194844 |
| Ebbesson SO et al. | Consumption of omega-3 fatty acids is not associated with a reduction in carotid atherosclerosis: the Genetics of Coronary Artery Disease in Alaska Natives study. | 2008 | Atherosclerosis | pmid:18054937 |
| Baldania SL et al. | RP-HPLC Estimation of Venlafaxine Hydrochloride in Tablet Dosage Forms. | 2008 | Indian J Pharm Sci | pmid:20390099 |
| Garay AS and Rodrigues DE | Effects of the inclusion of the spin label 10-doxyl-stearic acid on the structure and dynamics of model bilayers in water: stearic acid and stearic acid/cholesterol (50:20). | 2008 | J Phys Chem B | pmid:18198858 |
| Patel DM and Patel MM | Optimization of fast dissolving etoricoxib tablets prepared by sublimation technique. | 2008 | Indian J Pharm Sci | pmid:20390084 |
| Widjaja E and Seah RK | Application of Raman microscopy and band-target entropy minimization to identify minor components in model pharmaceutical tablets. | 2008 | J Pharm Biomed Anal | pmid:17980994 |
| Jithan AV et al. | Development and evaluation of a chloramphenicol hypertonic ophthalmic solution. | 2008 | Indian J Pharm Sci | pmid:20390083 |
| Darwish IA et al. | New spectrofluorimetric method with enhanced sensitivity for determination of paroxetine in dosage forms and plasma. | 2008 | Anal Chem Insights | pmid:19609398 |
| Bacher C et al. | Granule fraction inhomogeneity of calcium carbonate/sorbitol in roller compacted granules. | 2008 | Int J Pharm | pmid:17765416 |
| Rahman N and Haque SM | Optimized and validated spectrophotometric methods for the determination of enalapril maleate in commercial dosage forms. | 2008 | Anal Chem Insights | pmid:19609388 |
| El-Enany N et al. | Spectrofluorimetric determination of oxamniquine in dosage forms and spiked human plasma through derivatization with 1-dimethylaminonaphthalene-5-sulphonyl chloride. | 2008 | J Fluoresc | pmid:18058206 |
| Yuan H et al. | Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. | 2008 | Int J Pharm | pmid:17714896 |
| Guchardi R et al. | Influence of fine lactose and magnesium stearate on low dose dry powder inhaler formulations. | 2008 | Int J Pharm | pmid:17689898 |
| Hamad ML et al. | Functionality of magnesium stearate derived from bovine and vegetable sources: dry granulated tablets. | 2008 | J Pharm Sci | pmid:18351597 |
| Houmadi S et al. | Langmuir-Blodgett film of hydrophobin protein from Pleurotus ostreatus at the air-water interface. | 2008 | Langmuir | pmid:18925762 |
| Crowe FL et al. | Fatty acid composition of plasma phospholipids and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition. | 2008 | Am. J. Clin. Nutr. | pmid:18996872 |
| Isaev NP and Dzuba SA | Fast stochastic librations and slow rotations of spin labeled stearic acids in a model phospholipid bilayer at cryogenic temperatures. | 2008 | J Phys Chem B | pmid:18826269 |
| Koseki T et al. | Development of novel fast-disintegrating tablets by direct compression using sucrose stearic acid ester as a disintegration-accelerating agent. | 2008 | Chem. Pharm. Bull. | pmid:18827375 |
| Abbasi M et al. | Further investigation of lipid-substituted poly(L-Lysine) polymers for transfection of human skin fibroblasts. | 2008 | Biomacromolecules | pmid:18498191 |
| Hasegawa K et al. | Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH. | 2008 | Biochem. J. | pmid:18637792 |
| Lasserre R et al. | Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation. | 2008 | Nat. Chem. Biol. | pmid:18641634 |
| Aoki PH et al. | Sensor array made with nanostructured films to detect a phenothiazine compound. | 2008 | J Nanosci Nanotechnol | pmid:19049023 |
| Balk M et al. | Desulfatirhabdium butyrativorans gen. nov., sp. nov., a butyrate-oxidizing, sulfate-reducing bacterium isolated from an anaerobic bioreactor. | 2008 | Int. J. Syst. Evol. Microbiol. | pmid:18175693 |
| Chatterjee A and Chowdhury R | Bile and unsaturated fatty acids inhibit the binding of cholera toxin and Escherichia coli heat-labile enterotoxin to GM1 receptor. | 2008 | Antimicrob. Agents Chemother. | pmid:17954701 |
| Karoussi O and Hamouda AA | Macroscopic and nanoscale study of wettability alteration of oil-wet calcite surface in presence of magnesium and sulfate ions. | 2008 | J Colloid Interface Sci | pmid:17931645 |
| Fujio J et al. | Regulation of gut-derived resistin-like molecule beta expression by nutrients. | 2008 | Diabetes Res. Clin. Pract. | pmid:17936398 |
| Smirnov AI | Post-processing of EPR spectra by convolution filtering: calculation of a harmonics' series and automatic separation of fast-motion components from spin-label EPR spectra. | 2008 | J. Magn. Reson. | pmid:17967556 |
| Liu C et al. | In situ intestinal absorption of cyclosporine A solid dispersion in rats. | 2008 | Drug Dev Ind Pharm | pmid:18568913 |
| Gotoh K et al. | A quartz crystal microbalance simulation to examine the effect of ultraviolet light treatment on characteristics of polyethylene surface. | 2008 | J Oleo Sci | pmid:18685232 |
| Adeagbo AA and Alebiowu G | Evaluation of cocoa butter as potential lubricant for coprocessing in pharmaceutical tablets. | 2008 | Pharm Dev Technol | pmid:18484488 |
| Cai JY et al. | [Studies on chemical constituents from Anoectochilus roxburghii]. | 2008 | Zhong Yao Cai | pmid:18619237 |
| Ma BJ et al. | [Chemical constituents study on the fruiting bodies of Lactarius rufus]. | 2008 | Zhong Yao Cai | pmid:18619269 |
| Fini A et al. | Raman and thermal analysis of indomethacin/PVP solid dispersion enteric microparticles. | 2008 | Eur J Pharm Biopharm | pmid:18621516 |
| Liu LX et al. | Effect of particle properties on the flowability of ibuprofen powders. | 2008 | Int J Pharm | pmid:18652883 |
| Lumor SE et al. | Optimization of solid fat content and crystal properties of a trans-free structured lipid by blending with palm midfraction. | 2008 | J. Agric. Food Chem. | pmid:18781758 |
| Moon CD et al. | Reclassification of Clostridium proteoclasticum as Butyrivibrio proteoclasticus comb. nov., a butyrate-producing ruminal bacterium. | 2008 | Int. J. Syst. Evol. Microbiol. | pmid:18768601 |
| Terés S et al. | Oleic acid content is responsible for the reduction in blood pressure induced by olive oil. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18772370 |
| Weber D et al. | Quantification of lubricant activity of magnesium stearate by atomic force microscopy. | 2008 | Drug Dev Ind Pharm | pmid:18777241 |
| Liu J et al. | Size-tunable near-infrared PbS nanoparticles synthesized from lead carboxylate and sulfur with oleylamine as stabilizer. | 2008 | Nanotechnology | pmid:21730651 |
| Kartal A et al. | Compatibility of chewing gum excipients with the amino acid L-cysteine and stability of the active substance in directly compressed chewing gum formulation. | 2008 | J. Pharm. Pharmacol. | pmid:18718115 |
| Kundu S et al. | Relaxation of bimolecular layer films on water surfaces. | 2008 | Langmuir | pmid:18665619 |
| Chandran S et al. | Design and Evaluation of Ethyl Cellulose Based Matrix Tablets of Ibuprofen with pH Modulated Release Kinetics. | 2008 | Indian J Pharm Sci | pmid:21394255 |