stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Visioli F et al. | Molecular targets of omega 3 and conjugated linoleic Fatty acids - "micromanaging" cellular response. | 2012 | Front Physiol | pmid:22393325 |
| Gellrich V et al. | Behavior of perfluorinated compounds in soils during leaching experiments. | 2012 | Chemosphere | pmid:22391048 |
| Dey S et al. | Formulation and optimization of sustained release Stavudine microspheres using response surface methodology. | 2011 | ISRN Pharm | pmid:22389855 |
| Prajapati ST et al. | Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. | 2011 | ISRN Pharm | pmid:22389845 |
| Qu J et al. | Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. | 2012 | Biotechnol Biofuels | pmid:22377043 |
| Yin AW and Huang SJ | [Research on chemical constituents of xuefu zhuyu decoction]. | 2011 | Zhong Yao Cai | pmid:22372145 |
| Som I et al. | Status of surfactants as penetration enhancers in transdermal drug delivery. | 2012 | J Pharm Bioallied Sci | pmid:22368393 |
| Honkanen AM et al. | Characterization of the disappearance and formation of biohydrogenation intermediates during incubations of linoleic acid with rumen fluid in vitro. | 2012 | J. Dairy Sci. | pmid:22365221 |
| Ghanam RH et al. | Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. | 2012 | Front Microbiol | pmid:22363329 |
| Kim DH et al. | Fabrication of pseudo-ceramide-based lipid microparticles for recovery of skin barrier function. | 2012 | Colloids Surf B Biointerfaces | pmid:22361356 |
| Al-Ghamdi AF et al. | Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. | 2012 | Chem Cent J | pmid:22353684 |
| Stanisz B et al. | Effect of pharmaceutical excipients on the stability of angiotensin-converting enzyme inhibitors in their solid dosage formulations. | 2013 | Drug Dev Ind Pharm | pmid:22348774 |
| Choi du H et al. | A new experimental design method to optimize formulations focusing on a lubricant for hydrophilic matrix tablets. | 2012 | Drug Dev Ind Pharm | pmid:22348254 |
| Broderick PA and Kolodny EH | Biosensors for brain trauma and dual laser doppler flowmetry: enoxaparin simultaneously reduces stroke-induced dopamine and blood flow while enhancing serotonin and blood flow in motor neurons of brain, in vivo. | 2011 | Sensors (Basel) | pmid:22346571 |
| Muro M et al. | Molecular rearrangement in a zinc stearate Langmuir film dependent on a film preparation method studied using polarization-modulation infrared reflection absorption spectroscopy and X-ray absorption fine structure. | 2012 | J Phys Chem B | pmid:22339471 |
| Li D et al. | Ruminal microbe of biohydrogenation of trans-vaccenic acid to stearic acid in vitro. | 2012 | BMC Res Notes | pmid:22336099 |
| Walash MI et al. | Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. | 2012 | Chem Cent J | pmid:22333299 |
| Morales A et al. | Quantitative analysis of hydroperoxy-, keto- and hydroxy-dienes in refined vegetable oils. | 2012 | J Chromatogr A | pmid:22321954 |
| Milanovic J et al. | Microencapsulation of flavors in carnauba wax. | 2010 | Sensors (Basel) | pmid:22315575 |
| Veit M and Thaa B | Association of influenza virus proteins with membrane rafts. | 2011 | Adv Virol | pmid:22312341 |
| Sharma A and Chauhan RS | In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. | 2012 | Comp. Funct. Genomics | pmid:22312320 |
| Darwish IA et al. | Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate. | 2012 | Chem Cent J | pmid:22305461 |
| Ahn BJ et al. | Solvent-free acid-catalyzed ring-opening of epoxidized oleochemicals using stearates/stearic acid, and its applications. | 2012 | J. Agric. Food Chem. | pmid:22304525 |
| Okoye P et al. | To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis. | 2012 | Drug Dev Ind Pharm | pmid:22304483 |
| Wadher KJ et al. | Formulation and evaluation of a sustained-release tablets of metformin hydrochloride using hydrophilic synthetic and hydrophobic natural polymers. | 2011 | Indian J Pharm Sci | pmid:22303065 |
| Yee JK et al. | Subcutaneous adipose tissue fatty acid desaturation in adults with and without rare adipose disorders. | 2012 | Lipids Health Dis | pmid:22300160 |
| Nussbaum M and Paz Y | Ultra-thin SiO2 layers on TiO2: improved photocatalysis by enhancing products' desorption. | 2012 | Phys Chem Chem Phys | pmid:22298253 |
| Gabirot M et al. | Differences in Chemical Sexual Signals May Promote Reproductive Isolation and Cryptic Speciation between Iberian Wall Lizard Populations. | 2012 | Int J Evol Biol | pmid:22288019 |
| Nesarikar VV et al. | Instrumented roll technology for the design space development of roller compaction process. | 2012 | Int J Pharm | pmid:22286023 |
| Kim S et al. | Lipid-binding properties of TRIM72. | 2012 | BMB Rep | pmid:22281009 |
| El-Enany NM et al. | Development and validation of a repharsed phase- HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma. | 2012 | Chem Cent J | pmid:22277722 |
| Vega Mercado F et al. | Modulation of the domain topography of biphasic monolayers of stearic acid and dimyristoyl phosphatidylcholine. | 2012 | Chem. Phys. Lipids | pmid:22274694 |
| Anton N et al. | A new application of lipid nanoemulsions as coating agent, providing zero-order hydrophilic drug release from tablets. | 2012 | J Drug Deliv | pmid:22272376 |
| Zhen Z and Xie J | Development of manganese-based nanoparticles as contrast probes for magnetic resonance imaging. | 2012 | Theranostics | pmid:22272218 |
| Weber K et al. | Lesions in the Larynx of Wistar RccHan: WIST Rats. | 2009 | J Toxicol Pathol | pmid:22271998 |
| Sabir A et al. | The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.). | 2012 | J. Sci. Food Agric. | pmid:22271548 |
| Aissa I et al. | Synthesis of lipophilic tyrosyl esters derivatives and assessment of their antimicrobial and antileishmania activities. | 2012 | Lipids Health Dis | pmid:22264330 |
| Park MY et al. | Hog millet (Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice. | 2011 | Nutr Res Pract | pmid:22259675 |
| Liu Z et al. | [Chemical constituents from root bark of Tripterygium hypoglaucum]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22256754 |
| Basu B et al. | Formulation and evaluation of fast dissolving tablets of cinnarizine using superdisintegrant blends and subliming material. | 2011 | J Adv Pharm Technol Res | pmid:22247895 |
| Aly S | Detachment and recovery index: A new parameter measuring powder compressibility. | 2010 | J Adv Pharm Technol Res | pmid:22247881 |
| Shaikh SA et al. | Formulation and evaluation of s-(-)-amlodipine besylate and nebivolol hydrochloride tablets. | 2010 | J Adv Pharm Technol Res | pmid:22247846 |
| Nagaich U et al. | Design and evaluation of a metronidazole central core matrix tablet. | 2010 | J Adv Pharm Technol Res | pmid:22247836 |
| Bhattacharya S and Nagaich U | Assessment of anti-nociceptive efficacy of costus speciosus rhizome in swiss albino mice. | 2010 | J Adv Pharm Technol Res | pmid:22247830 |
| Zhang Y and Clapp A | Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. | 2011 | Sensors (Basel) | pmid:22247651 |
| Lu J et al. | A molecular mechanism for modulating plasma Zn speciation by fatty acids. | 2012 | J. Am. Chem. Soc. | pmid:22239162 |
| Wang K et al. | Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. | 2011 | Int J Nanomedicine | pmid:22238509 |
| Casiraghi A et al. | The influence of the polar head and the hydrophobic chain on the skin penetration enhancement effect of poly(ethylene glycol) derivatives. | 2012 | AAPS PharmSciTech | pmid:22232021 |
| Ghadiri M et al. | Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size. | 2012 | Int J Pharm | pmid:22227603 |
| Quintela M et al. | Estimation of the uncertainty associated with the results based on the validation of chromatographic analysis procedures: application to the determination of chlorides by high performance liquid chromatography and of fatty acids by high resolution gas chromatography. | 2012 | J Chromatogr A | pmid:22227361 |
| Jishnu V et al. | Formulation and evaluation of cephalexin extended release matrix tablets using 3 factorial design. | 2011 | J Young Pharm | pmid:22224031 |
| Singh AV and Nath LK | Evaluation of acetylated moth bean starch as a carrier for controlled drug delivery. | 2012 | Int. J. Biol. Macromol. | pmid:22210486 |
| Wulff-Pérez M et al. | Controlling lipolysis through steric surfactants: new insights on the controlled degradation of submicron emulsions after oral and intravenous administration. | 2012 | Int J Pharm | pmid:22209995 |
| Stryjecki C et al. | Enzymatic activity and genetic variation in SCD1 modulate the relationship between fatty acids and inflammation. | 2012 | Mol. Genet. Metab. | pmid:22209225 |
| Scalia S et al. | Preparation and in vitro evaluation of salbutamol-loaded lipid microparticles for sustained release pulmonary therapy. | 2012 | J Microencapsul | pmid:22208706 |
| Borbon IA et al. | Lack of efficacy of curcumin on neurodegeneration in the mouse model of Niemann-Pick C1. | 2012 | Pharmacol. Biochem. Behav. | pmid:22202649 |
| Oosterveer MH et al. | Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. | 2011 | Nutr Metab (Lond) | pmid:22201701 |
| Guan Q et al. | Preparation and pharmacokinetics of solid lipid nanoparticles loaded with pueraria flavones. | 2011 | J Control Release | pmid:22195890 |
| Han L et al. | Starch stearate as a novel encapsulation wall material and its effect on oil-water interfacial tension. | 2011 | J Control Release | pmid:22195872 |
| Basseri S and Austin RC | Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. | 2012 | Biochem Res Int | pmid:22195283 |
| Seeliger JC et al. | Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. | 2012 | J. Biol. Chem. | pmid:22194604 |
| Simmons DM and Gierer DS | A material sparing test to predict punch sticking during formulation development. | 2012 | Drug Dev Ind Pharm | pmid:22181042 |
| Wei CC and Ge ZQ | Influence of electrolyte and poloxamer 188 on the aggregation kinetics of solid lipid nanoparticles (SLNs). | 2012 | Drug Dev Ind Pharm | pmid:22181005 |
| Severino P et al. | Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. | 2012 | J Drug Deliv | pmid:22175030 |
| Varshosaz J et al. | Lipid nanocapsule-based gels for enhancement of transdermal delivery of ketorolac tromethamine. | 2011 | J Drug Deliv | pmid:22175029 |
| Bazzini AA et al. | Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. | 2011 | PLoS ONE | pmid:22174812 |
| Imae R et al. | LYCAT, a homologue of C. elegans acl-8, acl-9, and acl-10, determines the fatty acid composition of phosphatidylinositol in mice. | 2012 | J. Lipid Res. | pmid:22172515 |
| Arora G et al. | Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum. | 2011 | J Adv Pharm Technol Res | pmid:22171313 |
| Sathiyaraj S et al. | Lornoxicam gastro retentive floating matrix tablets: Design and in vitro evaluation. | 2011 | J Adv Pharm Technol Res | pmid:22171312 |
| Solanki SS and Dahima R | Formulation and evaluation of aceclofenac mouth-dissolving tablet. | 2011 | J Adv Pharm Technol Res | pmid:22171305 |
| Negi JS et al. | Effect of bioadhesion on initial in vitro buoyancy of effervescent floating matrix tablets of ciprofloxacin HCL. | 2011 | J Adv Pharm Technol Res | pmid:22171304 |
| Stahl J et al. | The effect of formulation vehicles on the in vitro percutaneous permeation of ibuprofen. | 2011 | BMC Pharmacol. | pmid:22168832 |
| Patel K et al. | Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design. | 2012 | AAPS PharmSciTech | pmid:22167415 |
| Duong CT and Roper MG | A microfluidic device for the automated derivatization of free fatty acids to fatty acid methyl esters. | 2012 | Analyst | pmid:22166918 |
| Brown PN et al. | Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension. | 2011 Sep-Oct | J AOAC Int | pmid:22165004 |
| Zhang J et al. | Synthesis of NaYF(4):Yb/Er/Gd up-conversion luminescent nanoparticles and luminescence resonance energy transfer-based protein detection. | 2012 | Anal. Biochem. | pmid:22155069 |
| Becker S et al. | Optimization of hepatocarcinoma uptake with radiolabeled lipiodol: development of new lipiodol formulations with increased viscosity. | 2012 | Cancer Biother. Radiopharm. | pmid:22149684 |
| Tomuta I et al. | High-Throughput NIR-Chemometric Method for Meloxicam Assay from Powder Blends for Tableting. | 2011 Oct-Dec | Sci Pharm | pmid:22145112 |
| Nanjwade BK et al. | Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. | 2011 Oct-Dec | Sci Pharm | pmid:22145101 |
| Slobodkina GB et al. | Deferrisoma camini gen. nov., sp. nov., a moderately thermophilic, dissimilatory iron(III)-reducing bacterium from a deep-sea hydrothermal vent that forms a distinct phylogenetic branch in the Deltaproteobacteria. | 2012 | Int. J. Syst. Evol. Microbiol. | pmid:22140176 |
| de Bari O et al. | Ezetimibe: its novel effects on the prevention and the treatment of cholesterol gallstones and nonalcoholic Fatty liver disease. | 2012 | J Lipids | pmid:22132342 |
| Sharma S et al. | RP-HPLC Method for Simultaneous Estimation of Nitazoxanide and Ofloxacin in Tablets. | 2011 | Indian J Pharm Sci | pmid:22131628 |
| Lavigne JP et al. | Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections. | 2011 | BMC Res Notes | pmid:22126300 |
| Kang JH et al. | Effects of solid carriers on the crystalline properties, dissolution and bioavailability of flurbiprofen in solid self-nanoemulsifying drug delivery system (solid SNEDDS). | 2012 | Eur J Pharm Biopharm | pmid:22119666 |
| Niu J et al. | Octreotide-modified and pH-triggering polymeric micelles loaded with doxorubicin for tumor targeting delivery. | 2012 | Eur J Pharm Sci | pmid:22119655 |
| Streit MR et al. | High survival in young patients using a second generation uncemented total hip replacement. | 2012 | Int Orthop | pmid:22113735 |
| Morinaga N et al. | Synthesis of fatty acid sterol esters using cholesterol esterase from Trichoderma sp. AS59. | 2011 | Enzyme Microb. Technol. | pmid:22113022 |
| Pijls BG et al. | Polyethylene thickness is a risk factor for wear necessitating insert exchange. | 2012 | Int Orthop | pmid:22105569 |
| Steidl S et al. | Mâ‚… muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. | 2011 | PLoS ONE | pmid:22102904 |
| Chapple IL et al. | Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double-blind RCT. | 2012 | J. Clin. Periodontol. | pmid:22093005 |
| Jung HA and Augsburger LL | Application of a novel automatic disintegration apparatus for the development and evaluation of a direct compression rapidly disintegrating tablet. | 2012 | Drug Dev Ind Pharm | pmid:22091970 |
| Meissner M et al. | Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate. | 2011 | PLoS ONE | pmid:22087215 |
| Kasliwal N et al. | Formulation, development, and performance evaluation of metoclopramide HCl oro-dispersible sustained release tablet. | 2011 | Arch. Pharm. Res. | pmid:22076769 |
| Cheng YY et al. | A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. | 2011 | Int J Mol Sci | pmid:22072918 |
| Peng Q et al. | A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. | 2011 | Microb. Cell Fact. | pmid:22067554 |
| Reddy KR et al. | Rationale, challenges, and participants in a Phase II trial of a botanical product for chronic hepatitis C. | 2012 | Clin Trials | pmid:22058086 |
| Yu WL et al. | Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. | 2011 | Microb. Cell Fact. | pmid:22047615 |
| Akinsete JA et al. | Consumption of high ω-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice. | 2012 | Carcinogenesis | pmid:22045025 |
| Wu DJ et al. | Metabonomics-based omics study and atherosclerosis. | 2011 | J Clin Bioinforma | pmid:22040517 |
| Tay T et al. | Dissolution of a poorly water-soluble drug dry coated with magnesium and sodium stearate. | 2012 | Eur J Pharm Biopharm | pmid:22036990 |