stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zara GP et al. | Erythromycin and gastrointestinal motility. | 1987 | Lancet | pmid:2889954 |
| West AA et al. | The relationship between glycosyltransferase production and membrane fatty acid composition of Streptococcus sanguis NCTC 7865 grown in the presence of protonmotive force inhibitors. | 1987 | J. Gen. Microbiol. | pmid:2966234 |
| Ondrias K et al. | Spin label study of the perturbation effect of the local anaesthetics tetracaine and dibucaine on synaptosomes at pharmacological concentrations. | 1987 | Biochem. Pharmacol. | pmid:2825709 |
| Reddy TS and Bazan NG | Arachidonic acid, stearic acid, and diacylglycerol accumulation correlates with the loss of phosphatidylinositol 4,5-bisphosphate in cerebrum 2 seconds after electroconvulsive shock: complete reversion of changes 5 minutes after stimulation. | 1987 | J. Neurosci. Res. | pmid:2830409 |
| Feix JB et al. | Interactions of 14N:15N stearic acid spin-label pairs: effects of host lipid alkyl chain length and unsaturation. | 1987 | Biochemistry | pmid:2820479 |
| Rhoads DE et al. | Metabolism of saturated fatty acids by Paramecium tetraurelia. | 1987 | J. Lipid Res. | pmid:3430068 |
| Tonnet ML and Green AG | Characterization of the seed and leaf lipids of high and low linolenic acid flax genotypes. | 1987 | Arch. Biochem. Biophys. | pmid:3813554 |
| PospÃsilová B and Kubes J | [Stability of erythromycin stearate in coated tablets during the action of gastric juice in vitro]. | 1987 | Cesk Farm | pmid:3581192 |
| Worman CP et al. | Saturation index of blood cell membrane fatty acids before and after IFN treatment in hairy cell leukemia. | 1987 | Leukemia | pmid:3669764 |
| Caglayan S et al. | Is medical therapy effective for regional lymphadenitis following BCG vaccination? | 1987 | Am. J. Dis. Child. | pmid:3673975 |
| Venho VM et al. | The value of comparative bioavailability studies of marketed drugs in drug control. An example with erythromycin stearate. | 1987 | Methods Find Exp Clin Pharmacol | pmid:3683018 |
| Bridges CD et al. | Rhodopsin, vitamin A, and interstitial retinol-binding protein in the rd chicken. | 1987 | Invest. Ophthalmol. Vis. Sci. | pmid:3557867 |
| Hope MJ and Cullis PR | Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. | 1987 | J. Biol. Chem. | pmid:3558410 |
| Husebye ES and Flatmark T | Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. | 1987 | Biochim. Biophys. Acta | pmid:3607074 |
| Cavalleri A and Minoia C | Lead level of whole blood and plasma in workers exposed to lead stearate. | 1987 | Scand J Work Environ Health | pmid:3616550 |
| Seimiya T et al. | Effects of composition and molecular packing on ionic properties of lipid monolayer having both cationic and anionic head groups. | 1987 | Chem. Phys. Lipids | pmid:3621383 |
| Salminen S and Salminen E | Urinary excretion of orally administered oxalic acid in MYRJ 45-treated NMRI mice. | 1987 | Toxicol. Lett. | pmid:3590233 |
| Masuzawa Y et al. | Distribution of dietary trans-octadecenoate among acyl-CoA and other lipid fractions of rat liver and heart. | 1987 | Biochim. Biophys. Acta | pmid:3593750 |
| Kolesnick RN and Paley AE | 1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action. | 1987 | J. Biol. Chem. | pmid:3597411 |
| Habib NA et al. | Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas. | 1987 | Int J Colorectal Dis | pmid:3598325 |
| Pyörälä S | Effect of some vehicles used in intramammary mastitis preparations on inflammation indicators in milk. | 1987 | J. Vet. Pharmacol. Ther. | pmid:3656512 |
| Adebayo GI et al. | Time-dependent inhibition of theophylline elimination by erythromycin stearate. | 1986 Sep-Oct | Biopharm Drug Dispos | pmid:3779037 |
| Goto S et al. | Eudragit RS and RL (acrylic resins) microcapsules as pH insensitive and sustained release preparations of ketoprofen. | 1986 Oct-Dec | J Microencapsul | pmid:3508190 |
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| Alcalay J et al. | Asymptomatic liver injury due to erythromycin stearate. | 1986 Jul-Aug | Drug Intell Clin Pharm | pmid:3743417 |
| Thiel WJ and Sberna FJ | Fluidized bed film coating of an interactive powder mixture to produce microencapsulated 2-5 microns particles. | 1986 | J. Pharm. Pharmacol. | pmid:2871149 |
| Hattori T et al. | Attenuation by pentobarbital of free fatty acid and diacylglycerol liberation during global ischaemia in rat brain. | 1986 | Neurol. Res. | pmid:2871507 |
| Catalá A | Stearic acid desaturation in rat liver microsomes: stimulation by fatty acid binding protein. | 1986 | Acta Physiol Pharmacol Latinoam | pmid:2876583 |
| Gotoh K et al. | Effects of unsaturated fatty acids on the peroxisomal enzyme activities of Tetrahymena pyriformis. | 1986 | J. Biochem. | pmid:2880840 |
| Giudici TA et al. | Methylmalonic and propionic acidemias: lipid profiles of normal and affected human skin fibroblasts incubated with [1-14C]propionate. | 1986 | Biochem. Med. Metab. Biol. | pmid:2872907 |
| Crosby T et al. | Identification of ecdysone 22-long-chain fatty acyl esters in newly laid eggs of the cattle tick Boophilus microplus. | 1986 | Biochem. J. | pmid:3030275 |
| Ginóbili de MartÃnez MS et al. | Asymmetry of diacylglycerol metabolism in rat cerebral hemispheres. | 1986 | J. Neurochem. | pmid:3083043 |
| Smith DM and Waite M | Phospholipid metabolism in human neutrophil subfractions. | 1986 | Arch. Biochem. Biophys. | pmid:3083776 |
| Singh H and Poulos A | A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts. | 1986 | Arch. Biochem. Biophys. | pmid:3767370 |
| Goto S et al. | [Role of metal stearates in preparation of Eudragit RS-microcapsules containing sulfamethizole by evaporation process in water phase]. | 1986 | Yakugaku Zasshi | pmid:3701600 |
| Shah KB et al. | An investigation of some factors influencing plug formation and fill weight in a dosing disk-type automatic capsule-filling machine. | 1986 | J Pharm Sci | pmid:3701614 |
| Wan LS and Choong YL | The effect of excipients on the penetration of liquid into tablets. | 1986 | Pharm Acta Helv | pmid:3725815 |
| Sugimoto Y et al. | A 2H NMR study on alteration of the membrane organization of mouse B16 melanoma cells treated with 12-O-tetradecanoylphorbol-13-acetate. | 1986 | J. Biochem. | pmid:3818567 |
| Thompson W and Belina H | Rapid accumulation of diacyl lipid in rat liver microsomes by selective acylation of 2-acyl-sn-glycero-3-phosphorylserine. | 1986 | Biochim. Biophys. Acta | pmid:3707975 |
| Heape AM et al. | Technique for injection into the sciatic nerve of the mouse for quantitative in vivo metabolic studies. | 1986 | Anal. Biochem. | pmid:3717558 |
| Caponnetto A et al. | [Correlations between unsaturated fatty acids and medium C-chain triglycerides]. | 1986 | Boll. Soc. Ital. Biol. Sper. | pmid:3718739 |
| Beaumelle BD and Vial HJ | Modification of the fatty acid composition of individual phospholipids and neutral lipids after infection of the simian erythrocyte by Plasmodium knowlesi. | 1986 | Biochim. Biophys. Acta | pmid:3719005 |
| Peura P et al. | The effect of ethanol on the release of free fatty acids from the brain in vivo; a study with push-pull cannula. | 1986 | Arch. Toxicol. Suppl. | pmid:3468932 |
| Slomiany BL et al. | Mucus glycoprotein of human saliva: differences in the associated and covalently bound lipids with caries. | 1986 | Biochim. Biophys. Acta | pmid:3518803 |
| Mazière C et al. | Cyclic AMP increases incorporation of exogenous fatty acids into triacylglycerols in hamster fibroblasts. | 1986 | Lipids | pmid:3020335 |
| Chalupa W et al. | Ruminal fermentation in vivo as influenced by long-chain fatty acids. | 1986 | J. Dairy Sci. | pmid:3722545 |
| Villa P et al. | Effects of a new fluorinated macrolide (P-0501A) and other erythromycins on drug metabolizing enzymes in rat liver. | 1986 | J. Antibiot. | pmid:3084433 |
| Siegel I et al. | Inhibition of sperm motility and agglutination of sperm cells by free fatty acids in whole semen. | 1986 | Fertil. Steril. | pmid:2868925 |
| Johansson ME and Nicklasson M | Investigation of the film formation of magnesium stearate by applying a flow-through dissolution technique. | 1986 | J. Pharm. Pharmacol. | pmid:2869127 |
| Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |