stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bertram J and Erwin JA | Isolation of a stearoyl CoA Desaturase form Tetrahymena thermophila. | 1981 | J. Protozool. | pmid:6114174 |
| Udeala OK et al. | Preliminary evaluation of dika fat, a new tablet lubricant. | 1980 | J. Pharm. Pharmacol. | pmid:6102130 |
| Zentner GM et al. | Free fatty acid-induced platelet aggregation: studies with solubilized and nonsolubilized fatty acids. | 1981 | J Pharm Sci | pmid:6101166 |
| Ohki K et al. | Effect of alpha-tocopherol on lipid peroxidation and acyl chain mobility of liver microsomes from vitamin E-difficient rat. | 1984 | J. Nutr. Sci. Vitaminol. | pmid:6092586 |
| Roguinsky M and Serieys F | [Treatment of mastitis in dry cows: treatment of all cows vs treatment of infected cows only (author's transl)]. | 1977 | Ann. Rech. Vet. | pmid:606146 |
| Oriel JD et al. | Comparison of erythromycin stearate and oxytetracycline in the treatment of non-gonococcal urethritis: their efficacy against Chlamydia trachomatis. | 1977 | Scott Med J | pmid:601555 |
| Bolton P and Harwood JL | Fatty acid biosynthesis by a particulate preparation from germinating pea. | 1977 | Biochem. J. | pmid:579600 |
| Nicoletti R et al. | [Palmitic acid-stearic acid ratio with reference to the fatty tissue properties in the human species]. | 1979 May-Jun | Arch Kriminol | pmid:573992 |
| Yang YT et al. | Dietary lipid metabolism in lactating dairy cows. | 1978 | J. Dairy Sci. | pmid:568635 |
| Burns CP et al. | Fatty acid utilization by L1210 murine leukemia cells. | 1977 | Cancer Res. | pmid:558821 |
| Boggiano BG and Gleeson M | Gastric acid inactivation of erythromycin stearate in solid dosage forms. | 1976 | J Pharm Sci | pmid:5588 |
| Smith DD | Clinical trial of erythromycin stearate suspension. | 1971 | Med. J. Aust. | pmid:5577264 |
| Molloy PL and Eisenstadt JM | Erythromycin resistance in mouse L cells. | 1979 | Somatic Cell Genet. | pmid:531731 |
| Bell SM | A comparison of absorption after oral administration of erythromycin estolate and erythromycin stearate. | 1971 | Med. J. Aust. | pmid:5134726 |
| Yakatan GJ et al. | Single-dose fasting bioequivalence assessment of erythromycin stearate tablets in man. | 1979 | J Pharmacokinet Biopharm | pmid:512842 |
| Pinzauti S and La Porta E | Assay of a cetylpyridinium-dequalinium chlorides combination in compressed lozenges: uptake of quaternary ammonium salts by magnesium stearate. | 1979 Sep-Oct | J Pharm Belg | pmid:512830 |
| Caille MP et al. | [Acute forms of lead poisoning by lead stearate]. | 1971 | Arch Mal Prof | pmid:5123552 |
| Schmidt P et al. | [Acute inhalation toxicity of cadmium stearate]. | 1971 | Z Gesamte Hyg | pmid:5123074 |
| Rutland J et al. | The influence of food on the bioavailability of new formulations of erythromycin stearate and base. | 1979 | Br J Clin Pharmacol | pmid:508509 |
| Patil GS et al. | Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. | 1972 | J. Lipid Res. | pmid:5075503 |
| Price CJ and Rowe CE | Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. | 1972 | Biochem. J. | pmid:5075269 |
| Lesslauer W and Blasie JK | Direct determination of the structure of barium stearate multilayers by x-ray diffraction. | 1972 | Biophys. J. | pmid:5057749 |
| Conte U et al. | The effect of magnesium stearate and polytetrafluoroethylene as lubricants in direct compression of acetylsalicylic acid. | 1972 | Farmaco Prat | pmid:5049531 |
| Wosilait WD and Ryan MP | The effects of oleic acid, tolbutamide, and oxyphenbutazone on the binding of warfarin by human serum albumin. | 1979 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:504792 |
| Malmborg AS | Effect of food on absorption of erythromycin. A study of two derivatives, the stearate and the base. | 1979 | J. Antimicrob. Chemother. | pmid:500517 |
| Carlisle HN and Saslaw S | Therapy of staphylococcal infections in monkeys. VI. Comparison of clindamycin, erythromycin, and methicillin. | 1971 | Appl Microbiol | pmid:4994902 |
| McLeay AC and Beveridge J | Clinical trial of erythromycin stearate suspension. | 1971 | Med. J. Aust. | pmid:4929585 |
| Beleslin DB et al. | Hyperthermic effect of palmitate sodium, stearate sodium and oleate sodium injected into the cerebral ventricles of conscious cats. | 1974 | Neuropharmacology | pmid:4840846 |
| Caldwell HC | Dissolution of lithium and magnesium from lithium carbonate capsules containing magnesium stearate. | 1974 | J Pharm Sci | pmid:4830001 |
| Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. | 1973 | Yakugaku Zasshi | pmid:4797567 |
| Riordan JR et al. | Plasma membrane lipids of human diploid fibroblasts from normal individuals and patients with cystic fibrosis. | 1979 | Biochim. Biophys. Acta | pmid:476136 |
| Arya OP and Bosa CB | In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. | 1973 | Br J Vener Dis | pmid:4748409 |
| McLeay A and Cooke P | Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4694278 |
| Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. | 1972 | Yakugaku Zasshi | pmid:4675495 |
| Berend N et al. | Plasma and saliva concentrations for a new formulation of erythromycin stearate. | 1979 | Curr Med Res Opin | pmid:467089 |
| Kabara JJ et al. | Fatty acids and derivatives as antimicrobial agents. | 1972 | Antimicrob. Agents Chemother. | pmid:4670656 |
| Wahle KW and Garton GA | Desaturation of stearate by sheep tissue microsomal preparations. | 1972 | Biochem. J. | pmid:4643297 |
| Zackler J et al. | A mass screening program for the detection of gonorrhea. | 1972 | Am. J. Obstet. Gynecol. | pmid:4623083 |
| Holub BJ and Piekarski J | The formation of phosphatidylinositol by acylation of 2-acyl-sn-glycero-3-phosphorylinositol in rat liver microsomes. | 1979 | Lipids | pmid:459717 |
| Antimicrobial efficacy of erythromycin stearate. A report from the general Practitioner Research Group. | 1974 | Practitioner | pmid:4591200 | |
| Bhatia RP and Lordi NG | Conductivity and hardness changes in aged compacts. | 1979 | J Pharm Sci | pmid:458612 |
| Ryan DC et al. | Estolate and stearate forms of erythromycin in the treatment of acute beta haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4568626 |
| Bond JM et al. | The second international reference preparation of procaine benzylpenicillin in oil with aluminium monostearate. | 1973 | Bull. World Health Organ. | pmid:4541152 |
| Kasuya M et al. | Toxic effect of cadmium stearate on rat cerebellum in culture. | 1974 | Bull Environ Contam Toxicol | pmid:4474041 |
| Nielsen GD et al. | [Aspiration of talcum or powder containing zinc stearate by children]. | 1979 | Ugeskr. Laeg. | pmid:442270 |
| Doran TA et al. | Amniotic fluid lecithin/sphingomyelin ratio, palmitic acid, palmitic acid/stearic acid ratio, total cortisol, creatinine, and percentage of lipid-positive cells in assessment of fetal maturity and fetal pulmonary maturity: a comparison. | 1979 | Am. J. Obstet. Gynecol. | pmid:433991 |
| Moody G et al. | Lubricity measurements of magnesium stearate [proceedings]. | 1979 | J. Pharm. Pharmacol. | pmid:42749 |
| Eccleston GM | The structure and stability of O/W emulsions stabilised by polyethylene glycol 1000 monostearate/fatty alcohols [proceedings]. | 1979 | J. Pharm. Pharmacol. | pmid:42725 |
| Kaur R and Grant DJ | Solid dispersions of drugs in polyoxyethylene 40 stearate: dissolution rates and physico-chemical interactions [proceedings]. | 1979 | J. Pharm. Pharmacol. | pmid:42723 |
| Lerk CF et al. | Effect of microcrystalline cellulose on liquid penetration in and disintegration of directly compressed tablets. | 1979 | J Pharm Sci | pmid:423092 |
| Welling PG et al. | Plasma levels following single and repeated doses of erythromycin estolate and erythromycin stearate. | 1979 | J Pharm Sci | pmid:423080 |
| Butcher AE and Jones TM | Some physical characteristics of magnesium stearate. | 1972 | J. Pharm. Pharmacol. | pmid:4144914 |
| Nossel HL et al. | Inhibition of collagen-induced platelet aggregation by normal plasma. | 1971 | J. Clin. Invest. | pmid:4107268 |
| Galpin JR and Allen JC | The influence of micelle formation on lipoxygenase kinetics. | 1977 | Biochim. Biophys. Acta | pmid:409436 |
| Baker RR and Loh ZD | The subcellular distribution of free fatty acids released during post-decapitative ischemia in rat cerebral cortex. | 1985 | Can. J. Biochem. Cell Biol. | pmid:4084856 |
| Stubbs C et al. | Determination of erythromycin in serum and urine by high-performance liquid chromatography with ultraviolet detection. | 1985 | J Pharm Sci | pmid:4078714 |
| Griffiths G et al. | The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. | 1985 | Biochem. J. | pmid:4052051 |
| Plachy J et al. | In vitro biopharmaceutical test for wetting rate. | 1985 | Acta Pharm Hung | pmid:4050448 |
| Beckurts TE et al. | Kinetics of different 123I- and 14C-labelled fatty acids in normal and diabetic rat myocardium in vivo. | 1985 | Nucl Med Commun | pmid:4047532 |
| Bridges CD et al. | Vitamin A and interstitial retinol-binding protein in an eye with recessive retinitis pigmentosa. | 1985 | Invest. Ophthalmol. Vis. Sci. | pmid:4039711 |
| Sklan D et al. | Digestion and absorption of lipids and bile acids in sheep fed stearic acid, oleic acid, or tristearin. | 1985 | J. Dairy Sci. | pmid:4031186 |
| Ruwart MJ et al. | 16,16-Dimethyl PGE2 and fatty acids protect hepatocytes against CCl4-induced damage. | 1985 | In Vitro Cell. Dev. Biol. | pmid:4030626 |
| Fujii M et al. | Fatty acid compositions of triacylglycerols and phospholipids in hen liver lipid before and after sexual maturity. | 1985 | Poult. Sci. | pmid:4022907 |
| Roblot L et al. | Effect of lubricant level and applied compressional pressure on surface friction of tablets. | 1985 | J Pharm Sci | pmid:4020661 |
| Brown ST | Therapy for nonvenereal treponematoses: review of the efficacy of penicillin and consideration of alternatives. | 1985 May-Jun | Rev. Infect. Dis. | pmid:4012176 |
| Willcox RR | Mass treatment campaigns against the endemic treponematoses. | 1985 May-Jun | Rev. Infect. Dis. | pmid:4012173 |
| Uribe WR | Yaws in Colombia. | 1985 May-Jun | Rev. Infect. Dis. | pmid:4012172 |
| Harrison GA et al. | Resistance in oral streptococci after repeated three-dose erythromycin prophylaxis. | 1985 | J. Antimicrob. Chemother. | pmid:4008379 |
| Wood CB et al. | Reduction in the stearic to oleic acid ratio in the circulating red blood cells: a possible tumour marker in solid human neoplasms. | 1985 | Eur J Surg Oncol | pmid:4007173 |
| Tierno MA and Brenner RR | [Biochemistry of the developmental cycle of Triatoma infestans (Vinchuca). 2. Biosynthesis of fatty acids]. | 1979 | Acta Physiol Lat Am | pmid:400672 |
| Jones PJ et al. | Absorption of 13C-labeled stearic, oleic, and linoleic acids in humans: application to breath tests. | 1985 | J. Lab. Clin. Med. | pmid:3998617 |
| Walker KA and Harwood JL | Localization of chloroplastic fatty acid synthesis de novo in the stroma. | 1985 | Biochem. J. | pmid:3994672 |
| Hegde RP et al. | Studies of powder flow using a recording powder flowmeter and measurement of the dynamic angle of repose. | 1985 | J Pharm Sci | pmid:3981409 |
| Saarni H et al. | Erythromycin levels in serum during treatment with erythromycin stearate and base. | 1979 | Ann. Clin. Res. | pmid:397800 |
| Carranco E et al. | Carbamazepine toxicity induced by concurrent erythromycin therapy. | 1985 | Arch. Neurol. | pmid:3977647 |
| Yamamoto O | Radiation-induced crosslinks between carboxylic acids and compounds of biological interest. | 1986 | Radiat. Res. | pmid:3952268 |
| Bankson DD et al. | Determination of retinyl esters and retinol in serum or plasma by normal-phase liquid chromatography: method and applications. | 1986 | Clin. Chem. | pmid:3940733 |
| Sakaguchi M et al. | Effects of dietary saturated and unsaturated fatty acids on fecal bile acids and colon carcinogenesis induced by azoxymethane in rats. | 1986 | Cancer Res. | pmid:3940210 |
| Kaplan E and Ansari K | High-performance liquid chromatography as a tool for identification of linolenic acid hydroperoxide prepared with soybean lipoxygenase. | 1985 | J. Chromatogr. | pmid:3937844 |
| Jones PJ et al. | Whole body oxidation of dietary fatty acids: implications for energy utilization. | 1985 | Am. J. Clin. Nutr. | pmid:3933323 |
| Galey CI et al. | Modulation of phospholipid metabolism in murine keratinocytes by tumor promoter, 12-O-tetradecanoylphorbol-13-acetate. | 1985 | J. Invest. Dermatol. | pmid:3930615 |
| George M and Chepenik KP | Phospholipase A activities in embryonic palate mesenchyme cells in vitro. | 1985 | Biochim. Biophys. Acta | pmid:3927980 |
| Wood CB et al. | Increase of oleic acid in erythrocytes associated with malignancies. | 1985 | Br Med J (Clin Res Ed) | pmid:3926106 |
| Noble RC and Shand JH | Unsaturated fatty acid compositional changes and desaturation during the embryonic development of the chicken (Gallus domesticus). | 1985 | Lipids | pmid:3925271 |
| Habenicht AJ et al. | Cell cycle-dependent changes in arachidonic acid and glycerol metabolism in Swiss 3T3 cells stimulated by platelet-derived growth factor. | 1985 | J. Biol. Chem. | pmid:3918038 |
| Maiti H and Haye KR | Does detection of chlamydial antibodies by microimmunofluorescence help in managing chlamydial lower genital tract infection in women? | 1985 | Genitourin Med | pmid:3891584 |
| Shanson DC et al. | Erythromycin stearate, 1.5 g, for the oral prophylaxis of streptococcal bacteraemia in patients undergoing dental extraction: efficacy and tolerance. | 1985 | J. Antimicrob. Chemother. | pmid:3882657 |
| Onoda T et al. | Antitumor activity of D-mannosamine in vitro: cytotoxic effect produced by mannosamine in combination with free fatty acids on human leukemia T-cell lines. | 1985 | Jpn. J. Clin. Oncol. | pmid:3877190 |
| Apostolov K et al. | Reduction in the stearic to oleic acid ratio in leukaemic cells--a possible chemical marker of malignancy. | 1985 | Blut | pmid:3859340 |
| Goto S et al. | [Effect of magnesium stearate in preparation of eudragit RS-microcapsules containing drugs]. | 1985 | Yakugaku Zasshi | pmid:3835255 |
| Johansson ME | Investigations of the mixing time dependence of the lubricating properties of granular and powdered magnesium stearate. | 1985 | Acta Pharm. Suec. | pmid:3832785 |
| Politi LE et al. | Dexamethasone effect on free fatty acid and diacylglycerol accumulation during experimentally induced vasogenic brain edema. | 1985 | Neurochem Pathol | pmid:3831846 |
| Berlin E et al. | Influence of saturated and unsaturated fats on platelet fatty acids in cholesterol-fed rabbits. | 1987 | Atherosclerosis | pmid:3827974 |
| Ong DE et al. | Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine. | 1987 | J. Biol. Chem. | pmid:3818619 |
| Sugimoto Y et al. | A 2H NMR study on alteration of the membrane organization of mouse B16 melanoma cells treated with 12-O-tetradecanoylphorbol-13-acetate. | 1986 | J. Biochem. | pmid:3818567 |
| Tonnet ML and Green AG | Characterization of the seed and leaf lipids of high and low linolenic acid flax genotypes. | 1987 | Arch. Biochem. Biophys. | pmid:3813554 |
| Fraschini F et al. | Bactericidal action of an average dose of erythromycin in the bronchi. | 1979 | Curr Med Res Opin | pmid:38063 |
| Tsao FH | Selective use of palmitic acid over stearic acid for synthesis of phosphatidylcholine and phosphatidylglycerol in lung. | 1986 | Lipids | pmid:3796238 |
| Adebayo GI et al. | Time-dependent inhibition of theophylline elimination by erythromycin stearate. | 1986 Sep-Oct | Biopharm Drug Dispos | pmid:3779037 |
| Singh H and Poulos A | A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts. | 1986 | Arch. Biochem. Biophys. | pmid:3767370 |