stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nagai J et al. | Increased proportion of medium chain fatty acids in nystatin-resistant yeast mutants. | 1981 | Lipids | pmid:7022083 |
| Bonini de Romanelli IC et al. | Phosphatidic acid, phosphatidylinositol, phosphatidylserine and cardiolipin in the course of early embryonic development. Fatty acid composition and content in whole toad embryos and in mitochondrial fractions. | 1981 | Biochim. Biophys. Acta | pmid:6791698 |
| Smaby JM and Brockman HL | Novel surface phase containing cholesteryl esters. 2. Nonequivalence of cholesteryl arachidonate and those with 18-carbon, cis-unsaturated acyl groups. | 1981 | Biochemistry | pmid:7213606 |
| Rosenthal MD | Accumulation of neutral lipids by human skin fibroblasts: differential effects of saturated and unsaturated fatty acids. | 1981 | Lipids | pmid:7219087 |
| Hsia JC and Kwan NH | Human serum albumin: binding specificity and allosteric effect of parinarate and stearate. A dianionic spin label study. | 1981 | J. Biol. Chem. | pmid:6257712 |
| Cook HW | The influence of trans-acids on desaturation and elongation of fatty acids in developing brain. | 1981 | Lipids | pmid:7329212 |
| Hug G et al. | Reye's syndrome simulacra in liver of mice after treatment with chemical agents and encephalomyocarditis virus. | 1981 | Lab. Invest. | pmid:6265702 |
| d'Avila Nunes M | A spin label study of erythrocyte membranes during simulation of freezing. | 1981 | J. Membr. Biol. | pmid:7253007 |
| Zentner GM et al. | Free fatty acid-induced platelet aggregation: studies with solubilized and nonsolubilized fatty acids. | 1981 | J Pharm Sci | pmid:6101166 |
| Davis PJ et al. | Gel to liquid-crystalline transition temperatures of water dispersions of two pairs of positional isomers of unsaturated mixed-acid phosphatidylcholines. | 1981 | Biochemistry | pmid:7260060 |
| Ashworth EN and Christiansen MN | Effect of Temperature and BASF 13 338 on the Lipid Composition and Respiration of Wheat Roots. | 1981 | Plant Physiol. | pmid:16661741 |
| Bertram J and Erwin JA | Isolation of a stearoyl CoA Desaturase form Tetrahymena thermophila. | 1981 | J. Protozool. | pmid:6114174 |
| Pawełczyk E and Marciniec B | Kinetics of drug decomposition. Part 69: Effect of excipients on the thermal decomposition of the mixture of aminophenazone allobarbital and adiphenine hydrochloride in the solid. | 1981 | Pharmazie | pmid:6117089 |
| Kudoh T et al. | Metabolism of fatty acid-labeled cerebroside sulfate in cultured cells from controls and metachromatic leukodystrophy patients. Use in the prenatal identification of a false positive fetus. | 1981 | J. Lab. Clin. Med. | pmid:6117597 |
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| Sanders KL et al. | Relapse of Legionnaires' disease in a renal transplant recipient. | 1980 | Arch. Intern. Med. | pmid:6992727 |
| Fraser DG | Selection of an oral erythromycin product. | 1980 | Am J Hosp Pharm | pmid:6998290 |
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| Wenzel DG and Kleoppel JW | Incorporation of saturated and cis- and trans-unsaturated long chain fatty acids in rat myocytes and increased susceptibility to arrhythmias. | 1980 | Toxicology | pmid:7210021 |
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| Baker RR and Chang H | The fatty acid composition of lipids of neuronal and glial nuclear fractions isolated from 15-day-old rabbit cerebral cortex. | 1980 | Can. J. Biochem. | pmid:6161681 |
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| Holub BJ et al. | Relative suitability of 1-palmitoyl and 1-stearoyl homologues of 1-acyl-sn-glycerylphosphorylcholine and different acyl donors for phosphatidylcholine synthesis via acyl-CoA:1-acyl-sn-glycero-3-phosphorylcholine acyltransferase in rat lung microsomes. | 1980 | Can. J. Biochem. | pmid:7407680 |
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| Herrmann H and Gercken G | Incorporation of [1-14C]octadecanol into the lipids of Leishmania donovani. | 1980 | Lipids | pmid:7374369 |
| Craven PA et al. | Calcium-dependent action of osmolality on adenosine 3',5'-monophosphate accumulation in rat renal inner medulla: evidence for a relationship to calcium-responsive arachidonate release and prostaglandin synthesis. | 1980 | J. Clin. Invest. | pmid:6243313 |
| Marlin GE et al. | Plasma and sputum erythromycin concentrations in chronic bronchitis. | 1980 | Thorax | pmid:7434299 |
| Søndergaard D et al. | Magnesium stearate given perorally to rats. A short term study. | 1980 | Toxicology | pmid:7434368 |
| Colmano G et al. | Activation of antibacterial silver coatings on surgical implants by direct current: preliminary studies in rabbits. | 1980 | Am. J. Vet. Res. | pmid:7436092 |
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| Polnikorn N et al. | Penicillin concentrations in cerebrospinal fluid after different treatment regimens for syphilis. | 1980 | Br J Vener Dis | pmid:7448578 |
| Stavchansky S et al. | Correlation of in vivo bioavailability of erythromycin stearate tablets with in vitro tests. | 1980 | J Pharm Sci | pmid:7452460 |
| Kaur R et al. | Comparison of polyethylene glycol and polyoxyethylene stearate as excipients for solid dispersion systems of griseofulvin and tolbutamide I: phase equilibria. | 1980 | J Pharm Sci | pmid:7452463 |
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| Light ND and Bailey AJ | Polymeric C-terminal cross-linked material from type-I collagen. A modified method for purification, anomalous behaviour on gel filtration, molecular weight estimation, carbohydrate content and lipid content. | 1980 | Biochem. J. | pmid:7458897 |
| Pinzauti S and La Porta E | Assay of a cetylpyridinium-dequalinium chlorides combination in compressed lozenges: uptake of quaternary ammonium salts by magnesium stearate. | 1979 Sep-Oct | J Pharm Belg | pmid:512830 |
| Nicoletti R et al. | [Palmitic acid-stearic acid ratio with reference to the fatty tissue properties in the human species]. | 1979 May-Jun | Arch Kriminol | pmid:573992 |
| Stewart AG et al. | The release of a model low-dose drug (riboflavine) from hard gelatin capsule formulations. | 1979 | J. Pharm. Pharmacol. | pmid:32357 |
| Fraschini F et al. | Bactericidal action of an average dose of erythromycin in the bronchi. | 1979 | Curr Med Res Opin | pmid:38063 |