stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Young PM et al. | Characterization of a surface modified dry powder inhalation carrier prepared by "particle smoothing". | 2002 | J. Pharm. Pharmacol. | pmid:12396294 |
Ercoli N | [Clinical and experimental study on an anti-inflammatory preparation of topical use. The 10-undecentil-l-ll pseudothiourea (AHR-1911)]. | 1975 | Med Cutan Ibero Lat Am | pmid:1241792 |
Thies C | Development of injectable microcapsules for use in the treatment of narcotic addiction. | 1975 | Natl Inst Drug Abuse Res Monogr Ser | pmid:1241971 |
Rodante F et al. | Compatibility between active components of a commercial drug. | 2002 | Farmaco | pmid:12420879 |
Treadwell RM et al. | Glyceride stearic acid content and structure affect the energy available to growing rats. | 2002 | J. Nutr. | pmid:12421851 |
Korhonen M et al. | Rheological properties of three component creams containing sorbitan monoesters as surfactants. | 2002 | Int J Pharm | pmid:12429489 |
Yamaguchi M et al. | Synthesis and selectin-binding activity of N-deacetylsialyl Lewis X ganglioside. | 2002 | Carbohydr. Res. | pmid:12433475 |
Ring A et al. | Evidence for vesicles that mediate long-chain fatty acid uptake by human microvascular endothelial cells. | 2002 | J. Lipid Res. | pmid:12454271 |
Eitel K et al. | Different role of saturated and unsaturated fatty acids in beta-cell apoptosis. | 2002 | Biochem. Biophys. Res. Commun. | pmid:12470657 |
Vaithiyalingam SR et al. | Formulation and stability evaluation of ketoprofen sustained-release tablets prepared by fluid bed granulation with Carbopol 971P solution. | 2002 | Drug Dev Ind Pharm | pmid:12476869 |
Rege PR et al. | Chitinosan-drug complexes: effect of electrolyte on naproxen release in vitro. | 2003 | Int J Pharm | pmid:12480291 |
Su BN et al. | Activity-guided fractionation of the seeds of Ziziphus jujuba using a cyclooxygenase-2 inhibitory assay. | 2002 | Planta Med. | pmid:12494342 |
Dantas da Silva LL et al. | Antibacterial activity of a stearic acid derivative from Stemodia foliosa. | 2002 | Planta Med. | pmid:12494347 |
Kerti A et al. | Content of retinol and retinyl esters in blood plasma, liver, kidney and reproductive organs of Japanese quails. | 2002 | Acta Vet. Hung. | pmid:12498148 |
von Eggelkraut-Gottanka SG et al. | Roller compaction and tabletting of St. John's wort plant dry extract using a gap width and force controlled roller compactor. I. Granulation and tabletting of eight different extract batches. | 2002 | Pharm Dev Technol | pmid:12503525 |
von Eggelkraut-Gottanka SG et al. | Roller compaction and tabletting of St. John's wort plant dry extract using a gap width and force controlled roller compactor. II. Study of roller compaction variables on granule and tablet properties by a 3(3) factorial design. | 2002 | Pharm Dev Technol | pmid:12503526 |
Sobal G and Sinzinger H | Binding of [99mTc]chondroitin sulfate to scavenger receptors on human chondrocytes as compared to binding of oxidized [125I]LDL on human macrophages. | J. Recept. Signal Transduct. Res. | pmid:12503634 | |
Sugihara A et al. | Purification and characterization of a novel cholesterol esterase from Pseudomonas aeruginosa, with its application to cleaning lipid-stained contact lenses. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12506971 |
Papanikolaou S et al. | Accumulation of a cocoa-butter-like lipid by Yarrowia lipolytica cultivated on agro-industrial residues. | 2003 | Curr. Microbiol. | pmid:12520368 |
Whorton AR et al. | The metabolism of (1-14C) stearic acid in rat testicular tissue. | 1976 | Biochim. Biophys. Acta | pmid:1252481 |