stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fatouros DG et al. | Clinical studies with oral lipid based formulations of poorly soluble compounds. | 2007 | Ther Clin Risk Manag | pmid:18472981 |
| Yuan H et al. | Preparation and characteristics of nanostructured lipid carriers for control-releasing progesterone by melt-emulsification. | 2007 | Colloids Surf B Biointerfaces | pmid:17656075 |
| Kamilya T et al. | Incorporation of ovalbumin within cationic octadecylamine monolayer and a comparative study with zwitterionic DPPC and anionic stearic acid monolayer. | 2007 | J Colloid Interface Sci | pmid:17669414 |
| MuzÃková J and Nováková P | A study of the properties of compacts from silicified microcrystalline celluloses. | 2007 | Drug Dev Ind Pharm | pmid:17654026 |
| Zhu S et al. | Interaction of the acid soap of triethanolamine stearate and stearic acid with water. | 2007 | J Phys Chem B | pmid:17266256 |
| Matsuzaka T et al. | Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance. | 2007 | Nat. Med. | pmid:17906635 |
| Nande VS et al. | Sustained release microspheres of diclofenac sodium using PEGylated rosin derivatives. | 2007 | Drug Dev Ind Pharm | pmid:17891576 |
| Cunha-Filho MS et al. | Compatibility of the antitumoral beta-lapachone with different solid dosage forms excipients. | 2007 | J Pharm Biomed Anal | pmid:17890039 |
| Chen Y et al. | Formation of monodisperse and shape-controlled MnO nanocrystals in non-injection synthesis: self-focusing via ripening. | 2007 | J. Am. Chem. Soc. | pmid:17696349 |
| Krzeski P et al. | Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. | 2007 | Arthritis Res. Ther. | pmid:17958901 |
| Walden M et al. | The effect of ethanol on the release of opioids from oral prolonged-release preparations. | 2007 | Drug Dev Ind Pharm | pmid:17882730 |
| Mahomed K et al. | Erythrocyte omega-3, omega-6 and trans fatty acids in relation to risk of preeclampsia among women delivering at Harare Maternity Hospital, Zimbabwe. | 2007 | Physiol Res | pmid:16497090 |
| Ishioka T et al. | Infrared study on annealing effect on conformation of zinc stearate. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16875870 |
| Petelska AD et al. | Interfacial tension of the lipid membrane formed from lipid-fatty acid and lipid-amine systems. | 2007 | Bioelectrochemistry | pmid:16713376 |
| Malmberg P et al. | Localization of lipids in the aortic wall with imaging TOF-SIMS. | 2007 | Biochim. Biophys. Acta | pmid:17240191 |
| Kanthimathi M and Dhathathreyan A | Langmuir and Langmuir-Blodgett films of N-(4-octadecyloxy-2-hydroxybenzylidene) derivatives of amino acids. | 2007 | J Colloid Interface Sci | pmid:17306822 |
| Richter K et al. | Localization of fatty acids with selective chain length by imaging time-of-flight secondary ion mass spectrometry. | 2007 | Microsc. Res. Tech. | pmid:17393479 |
| Simi CK and Emilia Abraham T | Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery. | 2007 | Bioprocess Biosyst Eng | pmid:17278045 |
| Vighi E et al. | Re-dispersible cationic solid lipid nanoparticles (SLNs) freeze-dried without cryoprotectors: characterization and ability to bind the pEGFP-plasmid. | 2007 | Eur J Pharm Biopharm | pmid:17368876 |
| Xu B and Yan B | Photophysical properties of novel lanthanide (Tb3+, Dy3+, Eu3+) complexes with long chain para-carboxyphenol ester p-L-benzoate (L=dodecanoyloxy, myristoyloxy, palmitoyloxy and stearoyloxy). | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16815090 |
| Harrison V et al. | Magnesium supplementation and perinatal hypoxia: outcome of a parallel group randomised trial in pregnancy. | 2007 | BJOG | pmid:17578470 |
| Shimizu K et al. | Characterization of tableting using the OSDRC system. | 2007 | Pharm. Res. | pmid:17554609 |
| Ando M et al. | Development and evaluation of a novel dry-coated tablet technology for pellets as a substitute for the conventional encapsulation technology. | 2007 | Int J Pharm | pmid:17223295 |
| Teixeira AC et al. | Phase behaviour of stearic acid-stearonitrile mixtures. A thermodynamic study in bulk and at the air-water interface. | 2006 Nov-Dec | Chem. Phys. Lipids | pmid:17027948 |
| Wang Y and Wu W | In situ evading of phagocytic uptake of stealth solid lipid nanoparticles by mouse peritoneal macrophages. | 2006 May-Jun | Drug Deliv | pmid:16556570 |
| Uematsu Y et al. | Determination of magnesium stearate in capsule- or tablet-type supplements. | 2006 Mar-Apr | J AOAC Int | pmid:16640294 |
| KladnÃcková I et al. | Release of albumin from oligoester plastic matrices: effect of magnesium oxide and bivalent stearates. | 2006 Jan-Feb | Drug Deliv | pmid:16401590 |
| Fang Q et al. | Ascorbyl stearate inhibits cell proliferation and tumor growth in human ovarian carcinoma cells by targeting the PI3K/AKT pathway. | 2006 Jan-Feb | Anticancer Res. | pmid:16475700 |
| Templer J et al. | Influence of C18 long chain fatty acids on hydrogen metabolism. | 2006 Jan-Feb | Biotechnol. Prog. | pmid:16454511 |
| Staiger K et al. | Saturated, but not unsaturated, fatty acids induce apoptosis of human coronary artery endothelial cells via nuclear factor-kappaB activation. | 2006 | Diabetes | pmid:17065351 |
| Alves M and Peric M | An EPR study of the interfacial properties of phosphatidylcholine vesicles with different lipid chain lengths. | 2006 | Biophys. Chem. | pmid:16517048 |
| Nohynek GJ et al. | Repeated topical treatment, in contrast to single oral doses, with Vitamin A-containing preparations does not affect plasma concentrations of retinol, retinyl esters or retinoic acids in female subjects of child-bearing age. | 2006 | Toxicol. Lett. | pmid:16243460 |
| Grassi G et al. | Propaedeutic study for the delivery of nucleic acid-based molecules from PLGA microparticles and stearic acid nanoparticles. | 2006 | Int J Nanomedicine | pmid:17722283 |
| You JO et al. | Incorporation of quantum dots on virus in polycationic solution. | 2006 | Int J Nanomedicine | pmid:17722262 |
| Ramirez-Dorronsoro JC et al. | Chargeability measurements of selected pharmaceutical dry powders to assess their electrostatic charge control capabilities. | 2006 | AAPS PharmSciTech | pmid:17285749 |
| Huang YF et al. | One new anthraquinone from marine Streptomyces sp. FX-58. | 2006 | Nat. Prod. Res. | pmid:17127510 |
| Huber AH et al. | Fatty acid-specific fluorescent probes and their use in resolving mixtures of unbound free fatty acids in equilibrium with albumin. | 2006 | Biochemistry | pmid:17128966 |
| Sunagane N et al. | [Possibility of interactions between prescription drugs and OTC drugs (2nd report)--interaction between levodopa preparation and OTC Kampo medicines for upset stomach]. | 2006 | Yakugaku Zasshi | pmid:17077621 |
| Kumon M et al. | Novel approach to DPI carrier lactose with mechanofusion process with additives and evaluation by IGC. | 2006 | Chem. Pharm. Bull. | pmid:17077547 |
| Johnston WL et al. | The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegans embryo. | 2006 | BMC Biol. | pmid:17042944 |
| Kapuśniak J and Tomasik P | Lipid microencapsulation in starch. | 2006 | J Microencapsul | pmid:16801245 |
| MacDonald AM and Lucy CA | Highly efficient protein separations in capillary electrophoresis using a supported bilayer/diblock copolymer coating. | 2006 | J Chromatogr A | pmid:16777117 |
| Douliez JP et al. | Self-assembly of fatty acid-alkylboladiamine salts. | 2006 | Langmuir | pmid:16401110 |
| Chen G | An exfoliated polyamide-6/layered double hydroxide nanocomposite via in situ intercalative polymerization between positively charged inorganic platelets. | 2006 | J Nanosci Nanotechnol | pmid:16736781 |
| Raith K et al. | Towards a molecular characterization of pharmaceutical excipients: mass spectrometric studies of ethoxylated surfactants. | 2006 | Int J Pharm | pmid:16730931 |
| Pérez-Vich B et al. | Molecular analysis of the high stearic acid content in sunflower mutant CAS-14. | 2006 | Theor. Appl. Genet. | pmid:16362273 |
| Urai M et al. | Structural analysis of an extracellular polysaccharide produced by Rhodococcus rhodochrous strain S-2. | 2006 | Carbohydr. Res. | pmid:16676419 |
| Shibata Y et al. | Fluidity and tableting characteristics of a powder solid dispersion of the low melting drugs ketoprofen and ibuprofen with crospovidone. | 2006 | Drug Dev Ind Pharm | pmid:16638683 |
| Capková P et al. | Structure of montmorillonite cointercalated with stearic acid and octadecylamine: modeling, diffraction, IR spectroscopy. | 2006 | J Colloid Interface Sci | pmid:16631185 |
| Wei Y et al. | Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16492686 |
| Wang Y et al. | Chronic effects of different non-esterified fatty acids on pancreatic islets of rats. | 2006 | Endocrine | pmid:16622307 |
| Khairuzzaman A et al. | Zero-order release of aspirin, theophylline and atenolol in water from novel methylcellulose glutarate matrix tablets. | 2006 | Int J Pharm | pmid:16621361 |
| Demirbas A et al. | Adsorption thermodynamics of stearic acid onto bentonite. | 2006 | J. Hazard. Mater. | pmid:16386845 |
| Wang Y et al. | Chain orientation and headgroup structure in Langmuir monolayers of stearic acid and metal stearate (Ag, Co, Zn, and Pb) studied by infrared reflection-absorption spectroscopy. | 2006 | J Chem Phys | pmid:16613467 |
| Mora PC et al. | Differential scanning calorimetry as a screening technique in compatibility studies of DHEA extended release formulations. | 2006 | J Pharm Biomed Anal | pmid:16574368 |
| Ding EL et al. | Chocolate and prevention of cardiovascular disease: a systematic review. | 2006 | Nutr Metab (Lond) | pmid:16390538 |
| Hasegawa T et al. | Molecular orientation analysis of a single-monolayer Langmuir-Blodgett film on a thin glass plate by infrared multiple-angle incidence resolution spectrometry. | 2006 | Anal. Chem. | pmid:16536405 |
| Serebryakova MV et al. | Mass spectrometric sequencing and acylation character analysis of C-terminal anchoring segment from Influenza A hemagglutinin. | 2006 | Eur J Mass Spectrom (Chichester) | pmid:16531651 |
| Polat M | Kinetic estimation of the adsorbate distribution on the surface from adsorbed amounts. | 2006 | J Colloid Interface Sci | pmid:16445933 |
| Fernandez-Moya V et al. | Lipid characterization of a high-stearic sunflower mutant displaying a seed stearic acid gradient. | 2006 | J. Agric. Food Chem. | pmid:19127733 |
| Vanholder T et al. | Effect of non-esterified fatty acids on bovine theca cell steroidogenesis and proliferation in vitro. | 2006 | Anim. Reprod. Sci. | pmid:15978752 |
| Duan Y et al. | Effect of molecular sieves on lipase-catalyzed esterification of rutin with stearic acid. | 2006 | J. Agric. Food Chem. | pmid:16910711 |
| Kazmierczak SC et al. | Electron spin resonance spectroscopy of serum albumin: a novel new test for cancer diagnosis and monitoring. | 2006 | Clin. Chem. | pmid:16990414 |
| Shankar BV and Patnaik A | J-aggregates in matrix stabilized two-dimensional azobenzene derivatives. | 2006 | J Colloid Interface Sci | pmid:16844137 |
| Miranda LA et al. | Performance of UASB and DAEB reactors in the anaerobic digestion of synthetic wastewater containing sodium oleate and sodium stereate. | 2006 | Water Sci. Technol. | pmid:16939093 |
| Colla E et al. | Amaranthus cruentus flour edible films: influence of stearic acid addition, plasticizer concentration, and emulsion stirring speed on water vapor permeability and mechanical properties. | 2006 | J. Agric. Food Chem. | pmid:16939322 |
| Renaville B et al. | Eicosapentaenoic acid and 3,10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells. | 2006 | Br. J. Nutr. | pmid:16571147 |
| Fukuda S et al. | Augmentation of vaccenate production and suppression of vaccenate biohydrogenation in cultures of mixed ruminal microbes. | 2006 | J. Dairy Sci. | pmid:16507700 |
| Nazzal S and Khan MA | Controlled release of a self-emulsifying formulation from a tablet dosage form: stability assessment and optimization of some processing parameters. | 2006 | Int J Pharm | pmid:16563673 |
| Swaminathan V et al. | Measurement of the surface energy of lubricated pharmaceutical powders by inverse gas chromatography. | 2006 | Int J Pharm | pmid:16469458 |
| Barman S and Vasudevan S | Contrasting melting behavior of zinc stearate and zinc oleate. | 2006 | J Phys Chem B | pmid:16471580 |
| Wang ZJ et al. | Neuroprotective effect of the stearic acid against oxidative stress via phosphatidylinositol 3-kinase pathway. | 2006 | Chem. Biol. Interact. | pmid:16448636 |
| Mirmehrabi M et al. | Thermodynamic modeling of activity coefficient and prediction of solubility: Part 2. Semipredictive or semiempirical models. | 2006 | J Pharm Sci | pmid:16493593 |
| Mirmehrabi M et al. | Thermodynamic modeling of activity coefficient and prediction of solubility: Part 1. Predictive models. | 2006 | J Pharm Sci | pmid:16493594 |
| Matsumoto K et al. | Electron paramagnetic resonance decay constant and oxidative stresses in liver microsomes of the selenium-deficient rat. | 2006 | J. Nutr. Biochem. | pmid:16517143 |
| Carr TP and Jesch ED | Food components that reduce cholesterol absorption. | 2006 | Adv. Food Nutr. Res. | pmid:17011476 |
| Salles HC et al. | The venomous secrets of the web droplets from the viscid spiral of the orb-weaver spider Nephila clavipes (Araneae, Tetragnatidae). | 2006 | Chem. Biodivers. | pmid:17193305 |
| Hirai N et al. | Improvement of the agitation granulation method to prepare granules containing a high content of a very hygroscopic drug. | 2006 | J. Pharm. Pharmacol. | pmid:17132205 |
| Müller H et al. | Control of CaCO3 crystallization by demixing of monolayers. | 2006 | Langmuir | pmid:17154582 |
| Song GY et al. | High-fat feeding reduces endothelium-dependent vasodilation in rats: differential mechanisms for saturated and unsaturated fatty acids? | 2006 | Clin. Exp. Pharmacol. Physiol. | pmid:16895544 |
| El Hagrasy AS et al. | Evaluation of risk and benefit in the implementation of near-infrared spectroscopy for monitoring of lubricant mixing. | 2006 | Pharm Dev Technol | pmid:16895841 |
| Rasmussen HE et al. | Reduction in cholesterol absorption is enhanced by stearate-enriched plant sterol esters in hamsters. | 2006 | J. Nutr. | pmid:17056791 |
| Brouwer DH et al. | Size selective dustiness and exposure; simulated workplace comparisons. | 2006 | Ann Occup Hyg | pmid:16524926 |
| Biswas S et al. | Formation of complex films with water-soluble CTAB molecules. | 2006 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16549387 |
| Suresh Y and Das UN | Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16412622 |
| Azevedo-Martins AK et al. | Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. | 2006 | Toxicol In Vitro | pmid:16644178 |
| iHoroz BB et al. | Influence of aluminum tristearate and sucrose stearate as the dispersing agents on physical properties and release characteristics of eudragit RS microspheres. | 2006 | AAPS PharmSciTech | pmid:16584146 |
| Hu FQ et al. | A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. | 2006 | Int J Pharm | pmid:16632285 |
| Schmidt WF et al. | Stearic acid solubility and cubic phase volume. | 2006 | Chem. Phys. Lipids | pmid:16616908 |
| Qi S et al. | An investigation into the interaction between taste masking fatty acid microspheres and alkaline buffer using thermal and spectroscopic analysis. | 2006 | J Pharm Sci | pmid:16552746 |
| Tsakalof AK et al. | Pitfalls in drying oils identification in art objects by gas chromatography. | 2006 | J Sep Sci | pmid:16922282 |
| Seitavuopio P et al. | Monitoring tablet surface roughness during the film coating process. | 2006 | AAPS PharmSciTech | pmid:16796349 |
| Govindarajan R et al. | Ionization states in the microenvironment of solid dosage forms: effect of formulation variables and processing. | 2006 | Pharm. Res. | pmid:16933092 |
| Shen Q et al. | Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies. | 2006 | Int J Pharm | pmid:16500056 |
| Zou T et al. | Support vector regression for determination of component of compound oxytetracycline powder on near-infrared spectroscopy. | 2006 | Anal. Biochem. | pmid:16723110 |
| Planinsek O et al. | Surface analysis of powder binary mixtures with ATR FTIR spectroscopy. | 2006 | Int J Pharm | pmid:16730933 |
| Söderhäll I et al. | Characterization of a hemocyte intracellular fatty acid-binding protein from crayfish (Pacifastacus leniusculus) and shrimp (Penaeus monodon). | 2006 | FEBS J. | pmid:16734719 |
| Hu FQ et al. | Novel self-aggregates of chitosan oligosaccharide grafted stearic acid: preparation, characterization and protein association. | 2006 | Pharmazie | pmid:16599258 |
| Killen BU and Corrigan OI | Effect of soluble filler on drug release from stearic acid based compacts. | 2006 | Int J Pharm | pmid:16600537 |
| Murphy DJ | The extracellular pollen coat in members of the Brassicaceae: composition, biosynthesis, and functions in pollination. | 2006 | Protoplasma | pmid:16937052 |