stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chen DB et al. | [In vitro and in vivo study of two kinds of long-circulating solid lipid nanoparticles containing paclitaxel]. | 2002 | Yao Xue Xue Bao | pmid:12579901 |
Ye YQ et al. | [Preparation and characterization of stearic acid-grafted chitosan oligosaccharide polymeric micelles]. | 2004 | Yao Xue Xue Bao | pmid:15491108 |
Li CC et al. | [In situ rat intestine absorption of paclitaxel-loaded solid lipid nanoparticles modified with cell-penetrating peptides]. | 2013 | Yao Xue Xue Bao | pmid:23600154 |
Chen JM et al. | [Comparison of seed oil physicochemical characteristics among three cultivars of Jatropha curcas L]. | 2009 | Ying Yong Sheng Tai Xue Bao | pmid:20353052 |
Chung DJ et al. | Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. | 2007 | Yonsei Med. J. | pmid:17461529 |
Hatipoglu ON and Tasan Y | A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. | 2000 | Yonsei Med. J. | pmid:10957888 |
Schmidt P et al. | [Animal experiments on barium stearate toxicity]. | 1975 | Z Gesamte Hyg | pmid:1189478 |
Schmidt P et al. | [Acute inhalation toxicity of cadmium stearate]. | 1971 | Z Gesamte Hyg | pmid:5123074 |
Murkovic M et al. | Variability of fatty acid content in pumpkin seeds (Cucurbita pepo L.). | 1996 | Z Lebensm Unters Forsch | pmid:8873459 |
Gonzalez-Castro MY et al. | Effects of blanching, freezing and freeze-drying on the fatty acid contents of green beans. | 1996 | Z Lebensm Unters Forsch | pmid:9123974 |
Shani J et al. | Efficacy of sustained-release radioprotective drugs in vivo. | 1987 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:2966504 |
Simpson JT et al. | Identification of major lipids from the scent gland secretions of Dumeril's ground boa (Acrantophis dumerili Jan) by gas chromatography-mass spectrometry. | 1988 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:3245880 |
Kraus G et al. | [The modification of different element levels in human blood by occupational cadmium exposure]. | 1988 | Zentralbl Bakteriol Mikrobiol Hyg B | pmid:3138836 |
Kankofer M et al. | The analysis of fatty acid content and phospholipase A2 activity in placenta of cows with and without retained fetal membranes. | 1996 | Zentralbl Veterinarmed A | pmid:8940891 |
el-Naghy MA et al. | Fungistatic action of natural oils and fatty acids on dermatophytic and saprophytic fungi. | 1992 | Zentralbl. Mikrobiol. | pmid:1609554 |
Zakhariv OIa and Ianovich VG | [The utilization of [9,10-(3)H] stearic and [1-(14)C] linolenic acids in the in-vitro synthesis of lipids in ruminant tissues]. | 1995 Jul-Aug | Zh. Evol. Biokhim. Fiziol. | pmid:8779280 |
Wang Y et al. | [Analysis of plasma metabonomics of mini-swines with qi deficiency and blood stasis syndrome due to chronic myocardial ischemia]. | 2011 | Zhong Xi Yi Jie He Xue Bao | pmid:21288451 |
Lian Z et al. | [Studies on chemical constituents of Choerospondias axillaris]. | 2003 | Zhong Yao Cai | pmid:12858769 |
Cai JY et al. | [Studies on chemical constituents from Anoectochilus roxburghii]. | 2008 | Zhong Yao Cai | pmid:18619237 |
Ma BJ et al. | [Chemical constituents study on the fruiting bodies of Lactarius rufus]. | 2008 | Zhong Yao Cai | pmid:18619269 |