stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Weaire PJ and Kekwick RG | The fractionation of the fatty acid synthetase activities of avocado mesocarp plastids. | 1975 | Biochem. J. | pmid:1156381 |
| Moon YA et al. | Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins. | 2001 | J. Biol. Chem. | pmid:11567032 |
| Shen Z et al. | Fatty acid composition of lysophosphatidic acid and lysophosphatidylinositol in plasma from patients with ovarian cancer and other gynecological diseases. | 2001 | Gynecol. Oncol. | pmid:11585410 |
| Nakanishi M et al. | Characterisation of myogenic cell membrane: II. Dynamic changes in membrane lipids during the differentiation of mouse C2 myoblast cells. | 2001 | Cell Biol. Int. | pmid:11589611 |
| Bézaire V et al. | Effects of fasting on muscle mitochondrial energetics and fatty acid metabolism in Ucp3(-/-) and wild-type mice. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11595653 |
| Haastrup A et al. | Lipids stimulate the production of 6-keto-prostaglandin f(1alpha) in human dorsal hand veins. | 2001 | Hypertension | pmid:11641299 |
| Baines DL et al. | Fatty acid modulation and sequence identity of fetal guinea pig alveolar type II cell amiloride-sensitive Na+ channel. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11676504 |
| Voinovich D et al. | Melt pelletization in high shear mixer using a hydrophobic melt binder: influence of some apparatus and process variables. | 2001 | Eur J Pharm Biopharm | pmid:11677073 |
| Rahamatalla AB et al. | Changes in fatty acids composition during seed growth and physicochemical characteristics of oil extracted from four safflower cultivars. | 2001 | Plant Foods Hum Nutr | pmid:11678443 |
| Maynar M et al. | Menopause-induced changes in lipid fractions and total fatty acids in plasma. | 2001 | Endocr. Res. | pmid:11678583 |
| Stehlin C et al. | X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation. | 2001 | EMBO J. | pmid:11689423 |
| Raila J et al. | Plasma transport and tissue distribution of beta-carotene, vitamin A and retinol-binding protein in domestic cats. | 2001 | Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. | pmid:11691620 |
| Finley JW and Davis CD | Manganese absorption and retention in rats is affected by the type of dietary fat. | 2001 | Biol Trace Elem Res | pmid:11697763 |
| Khabbaz F and Albertsson AC | Great advantages in using a natural rubber instead of a synthetic SBR in a pro-oxidant system for degradable LDPE. | 2000 | Biomacromolecules | pmid:11710197 |
| Mironova GD et al. | Palmitic and stearic acids bind Ca2+ with high affinity and form nonspecific channels in black-lipid membranes. Possible relation to Ca2+-activated mitochondrial pores. | 2001 | J. Bioenerg. Biomembr. | pmid:11710807 |
| Futaki S et al. | Stearylated arginine-rich peptides: a new class of transfection systems. | 2001 Nov-Dec | Bioconjug. Chem. | pmid:11716693 |
| Garzón Mde L and Villafuerte L | Compactibility of mixtures of calcium carbonate and microcrystalline cellulose. | 2002 | Int J Pharm | pmid:11719011 |
| Carballeira NM et al. | Identification and total synthesis of novel fatty acids from the Siphonarid limpet Siphonaria denticulata. | 2001 | J. Nat. Prod. | pmid:11720525 |
| Chen DB et al. | In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel. | 2001 | Chem. Pharm. Bull. | pmid:11724235 |
| Glew RH et al. | Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728165 |