stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Syamala US et al. | Assessment of formulation factors on the release behaviour of BCS Class II drug from tablet dosage form using DoE. | 2014 | Curr Drug Deliv | pmid:24975287 |
Liu J et al. | Functional investigations on embryonic stem cells labeled with clinically translatable iron oxide nanoparticles. | 2014 | Nanoscale | pmid:24969040 |
Tadros MI and Fahmy RH | Controlled-release triple anti-inflammatory therapy based on novel gastroretentive sponges: characterization and magnetic resonance imaging in healthy volunteers. | 2014 | Int J Pharm | pmid:24928130 |
Evoli S et al. | Molecular simulations of β-lactoglobulin complexed with fatty acids reveal the structural basis of ligand affinity to internal and possible external binding sites. | 2014 | Proteins | pmid:24916607 |
Loften JR et al. | Invited review: palmitic and stearic acid metabolism in lactating dairy cows. | 2014 | J. Dairy Sci. | pmid:24913651 |
Shah RM et al. | Physicochemical characterization of solid lipid nanoparticles (SLNs) prepared by a novel microemulsion technique. | 2014 | J Colloid Interface Sci | pmid:24910064 |
Park KH et al. | Elaidic acid (EA) generates dysfunctional high-density lipoproteins and consumption of EA exacerbates hyperlipidemia and fatty liver change in zebrafish. | 2014 | Mol Nutr Food Res | pmid:24863413 |
Salas JJ et al. | Biochemistry of high stearic sunflower, a new source of saturated fats. | 2014 | Prog. Lipid Res. | pmid:24858414 |
Gamble JF et al. | Monitoring process induced attrition of drug substance particles within formulated blends. | 2014 | Int J Pharm | pmid:24793838 |
Uğurlu T and Halaçoğlu MD | Effects of some lubricants and evaluation of compression parameters on directly compressible powders. | 2014 | Pharm Dev Technol | pmid:23590449 |
Chen FY et al. | TNYL peptide functional chitosan-g-stearate conjugate micelles for tumor specific targeting. | 2014 | Int J Nanomedicine | pmid:25298734 |
Li N et al. | Function of SREBP1 in the milk fat synthesis of dairy cow mammary epithelial cells. | 2014 | Int J Mol Sci | pmid:25250914 |
Shen MC et al. | Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice. | 2014 | PLoS ONE | pmid:25222131 |
Chen Y et al. | Stepwise encapsulation and controlled two-stage release system for cis-Diamminediiodoplatinum. | 2014 | Int J Nanomedicine | pmid:25061294 |
Ashraf SN et al. | Compositional studies and Biological activities of Perovskia abrotanoides Kar. oils. | 2014 | Biol. Res. | pmid:25052892 |
Zhang SW et al. | A method to evaluate the effect of contact with excipients on the surface crystallization of amorphous drugs. | 2014 | AAPS PharmSciTech | pmid:25037732 |
Yao JJ et al. | Efficient gene delivery system mediated by cis-aconitate-modified chitosan-g-stearic acid micelles. | 2014 | Int J Nanomedicine | pmid:24971010 |
López-Cervantes J et al. | Effect of solvents and methods of stirring in extraction of lycopene, oleoresin and fatty acids from over-ripe tomato. | 2014 | Int J Food Sci Nutr | pmid:24111501 |
Saerens L et al. | Validation of an in-line Raman spectroscopic method for continuous active pharmaceutical ingredient quantification during pharmaceutical hot-melt extrusion. | 2014 | Anal. Chim. Acta | pmid:24331054 |
Crowe FL et al. | Circulating fatty acids and prostate cancer risk: individual participant meta-analysis of prospective studies. | 2014 | J. Natl. Cancer Inst. | pmid:25210201 |